| Acetylcholinesterase Inhibitors as Disease-Modifying Therapies for Alzheimer s Disease DM Torrero Frontiers in Medicinal Chemistry: Volume 7, 34-86, 2015 | 322 | 2015 |
| New tacrine− huperzine A hybrids (huprines): Highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease P Camps, R El Achab, J Morral, D Muñoz-Torrero, A Badia, JE Baños, ... Journal of medicinal chemistry 43 (24), 4657-4666, 2000 | 260 | 2000 |
| Novel donepezil-based inhibitors of acetyl-and butyrylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation P Camps, X Formosa, C Galdeano, T Gómez, D Munoz-Torrero, ... Journal of medicinal chemistry 51 (12), 3588-3598, 2008 | 253 | 2008 |
| Pyrano[3,2-c]quinoline−6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and β-Amyloid-Directed Anti-Alzheimer Compounds P Camps, X Formosa, C Galdeano, D Munoz-Torrero, L Ramirez, ... Journal of medicinal chemistry 52 (17), 5365-5379, 2009 | 234 | 2009 |
| Synthesis, in Vitro Pharmacology, and Molecular Modeling of Very Potent Tacrine− Huperzine A Hybrids as Acetylcholinesterase Inhibitors of Potential Interest for the Treatment … P Camps, R El Achab, DM Görbig, J Morral, D Munoz-Torrero, A Badia, ... Journal of medicinal chemistry 42 (17), 3227-3242, 1999 | 176 | 1999 |
| 3D Structure of Torpedo californica Acetylcholinesterase Complexed with Huprine X at 2.1 Å Resolution: Kinetic and Molecular Dynamic Correlates, H Dvir, DM Wong, M Harel, X Barril, M Orozco, FJ Luque, ... Biochemistry 41 (9), 2970-2981, 2002 | 173 | 2002 |
| Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents E Viayna, I Sola, M Bartolini, A De Simone, C Tapia-Rojas, FG Serrano, ... Journal of Medicinal Chemistry 57 (6), 2549-2567, 2014 | 163 | 2014 |
| Huprine X is a novel high-affinity inhibitor of acetylcholinesterase that is of interest for treatment of Alzheimer's disease P Camps, B Cusack, WD Mallender, R El Achab, J Morral, ... Molecular pharmacology 57 (2), 409-417, 2000 | 159 | 2000 |
| Dimeric and hybrid anti-Alzheimer drug candidates D Munoz-Torrero, P Camps Current medicinal chemistry 13 (4), 399-422, 2006 | 142 | 2006 |
| Cholinergic drugs in pharmacotherapy of Alzheimer's disease P Camps, D Munoz-Torrero Mini Reviews in Medicinal Chemistry 2 (1), 11-25, 2002 | 127 | 2002 |
| Huprine–tacrine heterodimers as anti-amyloidogenic compounds of potential interest against Alzheimer’s and prion diseases C Galdeano, E Viayna, I Sola, X Formosa, P Camps, A Badia, MV Clos, ... Journal of medicinal chemistry 55 (2), 661-669, 2012 | 121 | 2012 |
| Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates P Camps, X Formosa, C Galdeano, T Gómez, D Muñoz-Torrero, ... Chemico-biological interactions 187 (1-3), 411-415, 2010 | 115 | 2010 |
| Synthesis and evaluation of tacrine–Huperzine a hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of alzheimer’s disease A Badia, JE Baños, P Camps, J Contreras, DM Görbig, D Muñoz-Torrero, ... Bioorganic & medicinal chemistry 6 (4), 427-440, 1998 | 111 | 1998 |
| Synthesis and pharmacological evaluation of huprine− tacrine heterodimers: Subnanomolar dual Binding site acetylcholinesterase inhibitors P Camps, X Formosa, D Muñoz-Torrero, J Petrignet, A Badia, MV Clos Journal of medicinal chemistry 48 (6), 1701-1704, 2005 | 104 | 2005 |
| Dual inhibitors of β-amyloid aggregation and acetylcholinesterase as multi-target anti-Alzheimer drug candidates E Viayna, R Sabate, D Muñoz-Torrero Current topics in medicinal chemistry 13 (15), 1820-1842, 2013 | 94 | 2013 |
| Combined in vitro cell-based/in silico screening of naturally occurring flavonoids and phenolic compounds as potential anti-Alzheimer drugs A Espargaró, T Ginex, MM Vadell, MA Busquets, J Estelrich, ... Journal of natural products 80 (2), 278-289, 2017 | 87 | 2017 |
| Novel Huprine Derivatives with Inhibitory Activity toward β‐Amyloid Aggregation and Formation as Disease‐Modifying Anti‐Alzheimer Drug Candidates E Viayna, T Gómez, C Galdeano, L Ramírez, M Ratia, A Badia, MV Clos, ... ChemMedChem 5 (11), 1855-1870, 2010 | 77 | 2010 |
| Polycyclic aminopyridine compounds which are acetylcholinesterase inhibitors, process for preparing them and their use PC Garcia, DMT Lopez-Ibarra, DMG Romeu, JC Lascorz, MS Fornell, ... US Patent 5,965,569, 1999 | 74 | 1999 |
| Tetrahydrobenzo [h][1, 6] naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies O Di Pietro, FJ Pérez-Areales, J Juárez-Jiménez, A Espargaro, MV Clos, ... European Journal of Medicinal Chemistry 84, 107-117, 2014 | 73 | 2014 |
| Synthesis, in vitro pharmacology, and molecular modeling of syn-huprines as acetylcholinesterase inhibitors P Camps, E Gómez, D Muñoz-Torrero, A Badia, NM Vivas, X Barril, ... Journal of medicinal chemistry 44 (26), 4733-4736, 2001 | 71 | 2001 |
Javier LuqueUniversity of Barcelona - Institut of BiomedicineDirección de correo verificada de ub.edu
