Reconciled rat and human metabolic networks for comparative toxicogenomics and biomarker predictions EM Blais, KD Rawls, BV Dougherty, ZI Li, GL Kolling, P Ye, A Wallqvist, ... Nature communications 8 (1), 14250, 2017 | 182 | 2017 |
Mechanistic identification of biofluid metabolite changes as markers of acetaminophen-induced liver toxicity in rats VR Pannala, KC Vinnakota, KD Rawls, SK Estes, TP O'Brien, RL Printz, ... Toxicology and applied pharmacology 372, 19-32, 2019 | 33 | 2019 |
A simplified metabolic network reconstruction to promote understanding and development of flux balance analysis tools KD Rawls, BV Dougherty, EM Blais, E Stancliffe, GL Kolling, K Vinnakota, ... Computers in Biology and Medicine 105, 64-71, 2019 | 31 | 2019 |
Identifying functional metabolic shifts in heart failure with the integration of omics data and a heart-specific, genome-scale model BV Dougherty, KD Rawls, GL Kolling, KC Vinnakota, A Wallqvist, ... Cell Reports 34 (10), 2021 | 19 | 2021 |
Genome-scale characterization of toxicity-induced metabolic alterations in primary hepatocytes KD Rawls, EM Blais, BV Dougherty, KC Vinnakota, VR Pannala, ... Toxicological Sciences 172 (2), 279-291, 2019 | 18 | 2019 |
Predicting changes in renal metabolism after compound exposure with a genome-scale metabolic model KD Rawls, BV Dougherty, KC Vinnakota, VR Pannala, A Wallqvist, ... Toxicology and applied pharmacology 412, 115390, 2021 | 14 | 2021 |
Validation of a multicellular tumor microenvironment system for modeling patient tumor biology and drug response DG Roller, SA Hoang, KD Rawls, KA Owen, MB Simmers, RA Figler, ... Scientific Reports 11 (1), 5535, 2021 | 7 | 2021 |
Metabolic network reconstructions to predict drug targets and off-target effects K Rawls, BV Dougherty, J Papin Metabolic Flux Analysis in Eukaryotic Cells: Methods and Protocols, 315-330, 2020 | 4 | 2020 |
Identifying metabolic adaptations characteristic of cardiotoxicity using paired transcriptomics and metabolomics data integrated with a computational model of heart metabolism BV Dougherty, CJ Moore, KD Rawls, ML Jenior, B Chun, S Nagdas, ... PLOS Computational Biology 20 (2), e1011919, 2024 | | 2024 |
Identifying metabolic adaptations during cardiotoxicity using paired transcriptomics and metabolomics data integrated with a model of heart metabolism BV Dougherty, KD Rawls, ML Jenior, B Chun, S Nagdas, JJ Saucerman, ... bioRxiv, 2021.10. 31.466544, 2021 | | 2021 |
Genome-Scale Characterization of Toxicity-Induced Metabolic Alterations in Primary KD Rawls, EM Blais, BV Dougherty, KC Vinnakota, VR Pannala, ... Nat Biotechnol 34 (5), 525-527, 2019 | | 2019 |