| Cell density effect in the baculovirus‐insect cells system: A quantitative analysis of energetic metabolism V Bernal, N Carinhas, AY Yokomizo, MJT Carrondo, PM Alves Biotechnology and bioengineering 104 (1), 162-180, 2009 | 135 | 2009 |
| Metabolic signatures of GS‐CHO cell clones associated with butyrate treatment and culture phase transition N Carinhas, TM Duarte, LC Barreiro, MJT Carrondo, PM Alves, ... Biotechnology and bioengineering 110 (12), 3244-3257, 2013 | 125 | 2013 |
| Metabolic responses of CHO cells to limitation of key amino acids TM Duarte, N Carinhas, LC Barreiro, MJT Carrondo, PM Alves, ... Biotechnology and Bioengineering 111 (10), 2095-2106, 2014 | 119 | 2014 |
| Improving baculovirus production at high cell density through manipulation of energy metabolism N Carinhas, V Bernal, F Monteiro, MJT Carrondo, R Oliveira, PM Alves Metabolic engineering 12 (1), 39-52, 2010 | 108 | 2010 |
| Insect cells as a production platform of complex virus-like particles F Fernandes, AP Teixeira, N Carinhas, MJT Carrondo, PM Alves Expert review of vaccines 12 (2), 225-236, 2013 | 104 | 2013 |
| In situ 2D fluorometry and chemometric monitoring of mammalian cell cultures AP Teixeira, CAM Portugal, N Carinhas, JML Dias, JP Crespo, PM Alves, ... Biotechnology and bioengineering 102 (4), 1098-1106, 2009 | 96 | 2009 |
| Toward system-level understanding of baculovirus–host cell interactions: from molecular fundamental studies to large-scale proteomics approaches F Monteiro, N Carinhas, MJT Carrondo, V Bernal, PM Alves Frontiers in microbiology 3, 391, 2012 | 76 | 2012 |
| Baculovirus production for gene therapy: the role of cell density, multiplicity of infection and medium exchange N Carinhas, V Bernal, AY Yokomizo, MJT Carrondo, R Oliveira, PM Alves Applied microbiology and biotechnology 81, 1041-1049, 2009 | 68 | 2009 |
| Hybrid metabolic flux analysis: combining stoichiometric and statistical constraints to model the formation of complex recombinant products N Carinhas, V Bernal, AP Teixeira, MJT Carrondo, PM Alves, R Oliveira BMC systems biology 5, 1-13, 2011 | 62 | 2011 |
| How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology? MJT Carrondo, PM Alves, N Carinhas, J Glassey, F Hesse, OW Merten, ... Biotechnology Journal 7 (12), 1522-1529, 2012 | 54 | 2012 |
| Systems biotechnology of animal cells: the road to prediction N Carinhas, R Oliveira, PM Alves, MJT Carrondo, AP Teixeira Trends in biotechnology 30 (7), 377-385, 2012 | 47 | 2012 |
| Hybrid semi-parametric mathematical systems: bridging the gap between systems biology and process engineering AP Teixeira, N Carinhas, JML Dias, P Cruz, PM Alves, MJT Carrondo, ... Journal of biotechnology 132 (4), 418-425, 2007 | 42 | 2007 |
| Quantitative proteomics of Spodoptera frugiperda cells during growth and baculovirus infection N Carinhas, AM Robitaille, S Moes, MJT Carrondo, P Jenoe, R Oliveira, ... PloS one 6 (10), e26444, 2011 | 38 | 2011 |
| Combining metabolic flux analysis tools and 13C NMR to estimate intracellular fluxes of cultured astrocytes AP Teixeira, SS Santos, N Carinhas, R Oliveira, PM Alves Neurochemistry international 52 (3), 478-486, 2008 | 38 | 2008 |
| 13C‐metabolic flux analysis of human adenovirus infection: Implications for viral vector production N Carinhas, A Koshkin, DAM Pais, PM Alves, AP Teixeira Biotechnology and bioengineering 114 (1), 195-207, 2017 | 29 | 2017 |
| Cell functional enviromics: unravelling the function of environmental factors AP Teixeira, JML Dias, N Carinhas, M Sousa, JJ Clemente, AE Cunha, ... BMC systems biology 5, 1-16, 2011 | 29 | 2011 |
| An integrated analysis of enzyme activities, cofactor pools and metabolic fluxes in baculovirus-infected Spodoptera frugiperda Sf9 cells V Bernal, F Monteiro, N Carinhas, R Ambrósio, PM Alves Journal of biotechnology 150 (3), 332-342, 2010 | 27 | 2010 |
| Metabolic flux profiling of MDCK cells during growth and canine adenovirus vector production N Carinhas, DAM Pais, A Koshkin, P Fernandes, AS Coroadinha, ... Scientific reports 6 (1), 23529, 2016 | 25 | 2016 |
| Projection to latent pathways (PLP): a constrained projection to latent variables (PLS) method for elementary flux modes discrimination AR Ferreira, JML Dias, AP Teixeira, N Carinhas, RMC Portela, IA Isidro, ... BMC Systems Biology 5, 1-13, 2011 | 19 | 2011 |
| 1H-NMR Protocol for Exometabolome Analysis of Cultured Mammalian Cells TM Duarte, N Carinhas, AC Silva, PM Alves, AP Teixeira Animal Cell Biotechnology: Methods and Protocols, 237-247, 2014 | 14 | 2014 |
