Dual gene activation and knockout screen reveals directional dependencies in genetic networks M Boettcher, R Tian, JA Blau, E Markegard, RT Wagner, D Wu, X Mo, ... Nature biotechnology 36 (2), 170-178, 2018 | 162 | 2018 |
Canonical Wnt/β-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression RT Wagner, X Xu, F Yi, BJ Merrill, AJ Cooney Stem cells 28 (10), 1794-1804, 2010 | 161 | 2010 |
Stem cell approaches for the treatment of type 1 diabetes mellitus RT Wagner, J Lewis, A Cooney, L Chan Translational Research 156 (3), 169-179, 2010 | 60 | 2010 |
Nucleolar-based Dux repression is essential for embryonic two-cell stage exit SQ Xie, BJ Leeke, C Whilding, RT Wagner, F Garcia-Llagostera, YX Low, ... Genes & development 36 (5-6), 331-347, 2022 | 37 | 2022 |
THAP1: role in mouse embryonic stem cell survival and differentiation F Aguilo, Z Zakirova, K Nolan, R Wagner, R Sharma, M Hogan, C Wei, ... Stem cell reports 9 (1), 92-107, 2017 | 36 | 2017 |
Evolutionary trace-based peptides identify a novel asymmetric interaction that mediates oligomerization in nuclear receptors P Gu, DH Morgan, M Sattar, X Xu, R Wagner, M Raviscioni, O Lichtarge, ... Journal of Biological Chemistry 280 (36), 31818-31829, 2005 | 35 | 2005 |
Alpha‐1 antitrypsin deficiency liver disease, mutational homogeneity modulated by epigenetic heterogeneity with links to obesity L Wang, GW Marek III, RA Hlady, RT Wagner, X Zhao, VC Clark, AX Fan, ... Hepatology 70 (1), 51-66, 2019 | 30 | 2019 |
The E3 ligase c‐Cbl regulates dendritic cell activation SH Chiou, P Shahi, RT Wagner, H Hu, N Lapteva, M Seethammagari, ... EMBO reports 12 (9), 971-979, 2011 | 22 | 2011 |
Minireview: the diverse roles of nuclear receptors in the regulation of embryonic stem cell pluripotency RT Wagner, AJ Cooney Molecular endocrinology 27 (6), 864-878, 2013 | 21 | 2013 |
OCT4: less is more RT Wagner, AJ Cooney Cell Research 19 (5), 527-528, 2009 | 13 | 2009 |
Identification of DNA methylation signatures associated with poor outcome in lower-risk Stage, Size, Grade and Necrosis (SSIGN) score clear cell renal cell cancer LY El Khoury, S Fu, RA Hlady, RT Wagner, L Wang, JE Eckel-Passow, ... Clinical epigenetics 13, 1-16, 2021 | 11 | 2021 |
SETD2 loss in renal epithelial cells drives epithelial‐to‐mesenchymal transition in a TGF‐β‐independent manner T Wang, RT Wagner, RA Hlady, X Pan, X Zhao, S Kim, L Wang, JH Lee, ... Molecular Oncology 18 (1), 44-61, 2024 | 8 | 2024 |
Extensive intratumor regional epigenetic heterogeneity in clear cell renal cell carcinoma targets kidney enhancers and is associated with poor outcome LY El Khoury, X Pan, RA Hlady, RT Wagner, S Shaikh, L Wang, ... Clinical Epigenetics 15 (1), 71, 2023 | 7 | 2023 |
Regulatable in vivo biotinylation expression system in mouse embryonic stem cells Q Wang, RT Wagner, AJ Cooney PLoS One 8 (5), e63532, 2013 | 5 | 2013 |
Nucleolar-based Dux repression is essential for 2-cell stage exit SQ Xie, BJ Leeke, C Whidling, RT Wagner, F Garcia-Llagostera, ... BioRxiv, 2021.11. 11.468235, 2021 | 4 | 2021 |
Development: sketch for a theory of Oct4 RT Wagner, TP Zwaka Current Biology 23 (22), R1014-R1016, 2013 | 4 | 2013 |
Epigenetic heterogeneity hotspots in human liver disease progression R Hlady, X Zhao, L El Khoury, R Wagner, A Luna, K Pham, ... Hepatology, 10.1097, 2024 | 3 | 2024 |
Hormone H Jensen, O Schales, W Zimmermann, MJ Schmulowitz, HB Wylie, ... Zeitschrift für analytische Chemie 123, 71-77, 1942 | 2 | 1942 |
SETD2 loss-of-function uniquely sensitizes cells to epigenetic targeting of NSD1-directed H3K36 methylation RT Wagner, RA Hlady, X Pan, L Wang, S Kim, X Zhao, LY El Khoury, ... Genome Biology 26 (1), 22, 2025 | 1 | 2025 |
Deciphering the interplay between SETD2 mediated H3K36me3 and RNA N6-methyladenosine in clear cell renal cell carcinoma (ccRCC) S Shaikh, X Zhao, RT Wagner, X Pan, RA Hlady, L Wang, TH Ho, ... Epigenetics 20 (1), 2456418, 2025 | | 2025 |