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Adam Rubin
Adam Rubin
Helen Hay Whitney Foundation Postdoctoral Fellow, Broad Institute
Dirección de correo verificada de broadinstitute.org
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An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
MR Corces, AE Trevino, EG Hamilton, PG Greenside, ...
Nature methods 14 (10), 959-962, 2017
21012017
HiChIP: efficient and sensitive analysis of protein-directed genome architecture
MR Mumbach, AJ Rubin, RA Flynn, C Dai, PA Khavari, WJ Greenleaf, ...
Nature methods 13 (11), 919-922, 2016
10792016
Multimodal analysis of composition and spatial architecture in human squamous cell carcinoma
AL Ji, AJ Rubin, K Thrane, S Jiang, DL Reynolds, RM Meyers, MG Guo, ...
Cell 182 (2), 497-514. e22, 2020
8322020
Measuring the activity of BioBrick promoters using an in vivo reference standard
JR Kelly, AJ Rubin, JH Davis, CM Ajo-Franklin, J Cumbers, MJ Czar, ...
Journal of biological engineering 3, 1-13, 2009
5132009
Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements
MR Mumbach, AT Satpathy, EA Boyle, C Dai, BG Gowen, SW Cho, ...
Nature genetics 49 (11), 1602-1612, 2017
4942017
Design, construction and characterization of a set of insulated bacterial promoters
JH Davis, AJ Rubin, RT Sauer
Nucleic acids research 39 (3), 1131-1141, 2011
4352011
Lineage-specific dynamic and pre-established enhancer–promoter contacts cooperate in terminal differentiation
AJ Rubin, BC Barajas, M Furlan-Magaril, V Lopez-Pajares, MR Mumbach, ...
Nature genetics 49 (10), 1522-1528, 2017
3062017
Coupled single-cell CRISPR screening and epigenomic profiling reveals causal gene regulatory networks
AJ Rubin, KR Parker, AT Satpathy, Y Qi, B Wu, AJ Ong, MR Mumbach, ...
Cell 176 (1), 361-376. e17, 2019
2862019
A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63
X Bao, AJ Rubin, K Qu, J Zhang, PG Giresi, HY Chang, PA Khavari
Genome biology 16, 1-17, 2015
1642015
Transcript-indexed ATAC-seq for precision immune profiling
AT Satpathy, N Saligrama, JD Buenrostro, Y Wei, B Wu, AJ Rubin, ...
Nature medicine 24 (5), 580-590, 2018
1362018
7SK-BAF axis controls pervasive transcription at enhancers
RA Flynn, BT Do, AJ Rubin, E Calo, B Lee, H Kuchelmeister, M Rale, ...
Nature structural & molecular biology 23 (3), 231-238, 2016
1182016
HiChIRP reveals RNA-associated chromosome conformation
MR Mumbach, JM Granja, RA Flynn, CM Roake, AT Satpathy, AJ Rubin, ...
Nature methods 16 (6), 489-492, 2019
912019
The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation
DS Kim, VI Risca, DL Reynolds, J Chappell, AJ Rubin, N Jung, ...
Nature genetics 53 (11), 1564-1576, 2021
652021
CSNK1a1 regulates PRMT1 to maintain the progenitor state in self-renewing somatic tissue
X Bao, Z Siprashvili, BJ Zarnegar, RM Shenoy, EJ Rios, N Nady, K Qu, ...
Developmental cell 43 (2), 227-239. e5, 2017
642017
Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment
JM Pattison, SP Melo, SN Piekos, JL Torkelson, E Bashkirova, ...
Nature genetics 50 (12), 1658-1665, 2018
552018
Genome-wide meta-analysis identifies eight new susceptibility loci for cutaneous squamous cell carcinoma
KY Sarin, Y Lin, R Daneshjou, A Ziyatdinov, G Thorleifsson, A Rubin, ...
Nature communications 11 (1), 820, 2020
432020
Divergent effects of canonical and non‐canonical TGF‐β signalling on mixed contractile‐synthetic smooth muscle cell phenotype in human Marfan syndrome aortic root aneurysms
AJ Pedroza, T Koyano, J Trojan, A Rubin, I Palmon, K Jaatinen, G Burdon, ...
Journal of Cellular and Molecular Medicine 24 (3), 2369-2383, 2020
372020
Omni-ATAC-seq: improved ATAC-seq protocol
MR Corces, SW Cho, HY Chang, WJ Greenleaf, TJ Montine, PA Khavari, ...
212017
Single-cell and spatial transcriptomic analysis of human skin delineates intercellular communication and pathogenic cells
K Thrane, MCG Winge, H Wang, L Chen, MG Guo, A Andersson, ...
Journal of Investigative Dermatology 143 (11), 2177-2192. e13, 2023
152023
Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival
CN Tzouanas, MS Sherman, JES Shay, AJ Rubin, BE Mead, TT Dao, ...
Biorxiv, 2023
52023
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Artículos 1–20