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| The Drosophila homology of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless F Rijsewijk, M Schuermann, E Wagenaar, P Parren, D Weigel, R Nusse Cell 50 (4), 649-657, 1987 | 1434 | 1987 |
| Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors M De Weers, YT Tai, MS Van Der Veer, JM Bakker, T Vink, DCH Jacobs, ... The Journal of Immunology 186 (3), 1840-1848, 2011 | 1237 | 2011 |
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| Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design EO Saphire, PWHI Parren, R Pantophlet, MB Zwick, GM Morris, PM Rudd, ... science 293 (5532), 1155-1159, 2001 | 1147 | 2001 |
| Bispecific antibodies: a mechanistic review of the pipeline AF Labrijn, ML Janmaat, JM Reichert, PWHI Parren Nature reviews Drug discovery 18 (8), 585-608, 2019 | 1112 | 2019 |
| Fc receptor but not complement binding is important in antibody protection against HIV AJ Hessell, L Hangartner, M Hunter, CEG Havenith, FJ Beurskens, ... Nature 449 (7158), 101-104, 2007 | 1076 | 2007 |
| Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41 MB Zwick, AF Labrijn, M Wang, C Spenlehauer, EO Saphire, JM Binley, ... Journal of virology 75 (22), 10892-10905, 2001 | 1045 | 2001 |
| Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas JL Teeling, RR French, MS Cragg, J van den Brakel, M Pluyter, H Huang, ... Blood 104 (6), 1793-1800, 2004 | 879 | 2004 |
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| Complement is activated by IgG hexamers assembled at the cell surface CA Diebolder, FJ Beurskens, RN De Jong, RI Koning, K Strumane, ... Science 343 (6176), 1260-1263, 2014 | 851 | 2014 |
| Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro PWHI Parren, PA Marx, AJ Hessell, A Luckay, J Harouse, C Cheng-Mayer, ... Journal of virology 75 (17), 8340-8347, 2001 | 837 | 2001 |
| Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques AJ Hessell, P Poignard, M Hunter, L Hangartner, DM Tehrani, WK Bleeker, ... Nature medicine 15 (8), 951-954, 2009 | 694 | 2009 |
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| Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma MB Overdijk, S Verploegen, M Bögels, M van Egmond, JJL van Bueren, ... MAbs 7 (2), 311-320, 2015 | 546 | 2015 |
| On the interaction of IgG subclasses with the low affinity Fc gamma RIIa (CD32) on human monocytes, neutrophils, and platelets. Analysis of a functional polymorphism to human IgG2. PW Parren, PA Warmerdam, LC Boeije, J Arts, NA Westerdaal, A Vlug, ... The Journal of clinical investigation 90 (4), 1537-1546, 1992 | 501 | 1992 |
| In vitro characterization of five humanized OKT3 effector function variant antibodies D Xu, ML Alegre, SS Varga, AL Rothermel, AM Collins, VL Pulito, ... Cellular immunology 200 (1), 16-26, 2000 | 428 | 2000 |
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| Targeting interleukin‐15 in patients with rheumatoid arthritis: a proof‐of‐concept study B Baslund, N Tvede, B Danneskiold‐Samsoe, P Larsson, G Panayi, ... Arthritis & Rheumatism 52 (9), 2686-2692, 2005 | 409 | 2005 |
Rob N. de JongGenmabDirección de correo verificada de genmab.com