Association of a functional single‐nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus … G Orozco, E Sánchez, MA González‐Gay, MA López‐Nevot, B Torres, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2005 | 379 | 2005 |
The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis B Rueda, G Orozco, E Raya, JL Fernandez-Sueiro, J Mulero, FJ Blanco, ... Annals of the rheumatic diseases 67 (10), 1451-1454, 2008 | 232 | 2008 |
Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci P Martin, A McGovern, G Orozco, K Duffus, A Yarwood, S Schoenfelder, ... Nature communications 6 (1), 10069, 2015 | 222 | 2015 |
Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis K Ishigaki, S Sakaue, C Terao, Y Luo, K Sonehara, K Yamaguchi, ... Nature genetics 54 (11), 1640-1651, 2022 | 210 | 2022 |
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways E López-Isac, M Acosta-Herrera, M Kerick, S Assassi, AT Satpathy, ... Nature communications 10 (1), 4955, 2019 | 164 | 2019 |
Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus G Orozco, S Eyre, A Hinks, J Bowes, AW Morgan, AG Wilson, ... Annals of the rheumatic diseases 70 (3), 463-468, 2011 | 164 | 2011 |
Polymorphisms of toll‐like receptor 2 and 4 genes in rheumatoid arthritis and systemic lupus erythematosus E Sanchez, G Orozco, MA Lopez‐Nevot, J Jimenez‐Alonso, J Martin Tissue antigens 63 (1), 54-57, 2004 | 154 | 2004 |
Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis J Bowes, G Orozco, E Flynn, P Ho, R Brier, H Marzo-Ortega, L Coates, ... Annals of the rheumatic diseases 70 (9), 1641-1644, 2011 | 138 | 2011 |
Association of STAT4 with rheumatoid arthritis: A replication study in three European populations G Orozco, BZ Alizadeh, AM Delgado‐Vega, MÁ González‐Gay, A Balsa, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2008 | 136 | 2008 |
Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23 G Orozco, A Hinks, S Eyre, X Ke, LJ Gibbons, J Bowes, E Flynn, P Martin, ... Human molecular genetics 18 (14), 2693-2699, 2009 | 133 | 2009 |
Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study G Orozco, S Eyre, A Hinks, X Ke, AG Wilson, DE Bax, AW Morgan, ... Annals of the rheumatic diseases 69 (5), 813-816, 2010 | 131 | 2010 |
Genetic basis of rheumatoid arthritis G Orozco, B Rueda, J Martin Biomedicine & Pharmacotherapy 60 (10), 656-662, 2006 | 128 | 2006 |
Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23 A McGovern, S Schoenfelder, P Martin, J Massey, K Duffus, D Plant, ... Genome biology 17, 1-15, 2016 | 101 | 2016 |
Analysis of a functional BTNL2 polymorphism in type 1 diabetes, rheumatoid arthritis, and systemic lupus erythematosus G Orozco, P Eerligh, E Sánchez, S Zhernakova, BO Roep, ... Human immunology 66 (12), 1235-1241, 2005 | 98 | 2005 |
Influence of HLA DRB1 alleles in the susceptibility of rheumatoid arthritis and the regulation of antibodies against citrullinated proteins and rheumatoid factor A Balsa, A Cabezón, G Orozco, T Cobo, E Miranda-Carus, ... Arthritis research & therapy 12, 1-8, 2010 | 97 | 2010 |
Macrophage migration inhibitory factor gene: influence on rheumatoid arthritis susceptibility A Martínez, G Orozco, J Varadé, MS López, D Pascual, A Balsa, A García, ... Human immunology 68 (9), 744-747, 2007 | 90 | 2007 |
Functional evaluation of TNFAIP3 (A20) in rheumatoid arthritis LM Elsby, G Orozco, J Denton, J Worthington, DW Ray, RP Donn Clinical and experimental rheumatology 28 (5), 708, 2010 | 88 | 2010 |
Epistatic interaction between FCRL3 and NFκB1 genes in Spanish patients with rheumatoid arthritis A Martinez, E Sánchez, A Valdivia, G Orozco, MA López-Nevot, ... Annals of the rheumatic diseases 65 (9), 1188-1191, 2006 | 86 | 2006 |
Synthetic associations in the context of genome-wide association scan signals G Orozco, JC Barrett, E Zeggini Human molecular genetics 19 (R2), R137-R144, 2010 | 84 | 2010 |
Novel Association of theInterleukin 2-Interleukin 21Region With Inflammatory Bowel Disease A Márquez, G Orozco, A Martínez, R Palomino-Morales, ... Official journal of the American College of Gastroenterology| ACG 104 (8 …, 2009 | 74 | 2009 |