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Rameshwar Patil
Rameshwar Patil
Associate Professor, Dept of Basic Science, Division of Cancer Science, Loma Linda University
Dirección de correo verificada de llu.edu
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Blood–brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy
A Galstyan, JL Markman, ES Shatalova, A Chiechi, AJ Korman, R Patil, ...
Nature Communications 10 (1), 3850, 2019
2652019
Nanoplatforms for constructing new approaches to cancer treatment, imaging, and drug delivery: what should be the policy?
B Kateb, K Chiu, KL Black, V Yamamoto, B Khalsa, JY Ljubimova, H Ding, ...
Neuroimage 54, S106-S124, 2011
2382011
Inhibition of brain tumor growth by intravenous poly (β-L-malic acid) nanobioconjugate with pH-dependent drug release
H Ding, S Inoue, AV Ljubimov, R Patil, J Portilla-Arias, J Hu, B Konda, ...
Proceedings of the National Academy of Sciences 107 (42), 18143-18148, 2010
2032010
Brain tumor tandem targeting using a combination of monoclonal antibodies attached to biopoly (β-L-malic acid)
M Fujita, BS Lee, NM Khazenzon, ML Penichet, KA Wawrowsky, R Patil, ...
Journal of Controlled Release 122 (3), 356-363, 2007
1192007
Cellular delivery of doxorubicin via pH-controlled hydrazone linkage using multifunctional nano vehicle based on poly (β-L-malic acid)
R Patil, J Portilla-Arias, H Ding, B Konda, A Rekechenetskiy, S Inoue, ...
International Journal of Molecular Sciences 13 (9), 11681-11693, 2012
1112012
Temozolomide delivery to tumor cells by a multifunctional nano vehicle based on poly (β-L-malic acid)
R Patil, J Portilla-Arias, H Ding, S Inoue, B Konda, J Hu, KA Wawrowsky, ...
Pharmaceutical research 27, 2317-2329, 2010
1022010
MRI virtual biopsy and treatment of brain metastatic tumors with targeted nanobioconjugates: nanoclinic in the brain
R Patil, AV Ljubimov, PR Gangalum, H Ding, J Portilla-Arias, S Wagner, ...
ACS nano 9 (5), 5594-5608, 2015
952015
Blockade of a laminin-411–notch axis with CRISPR/Cas9 or a nanobioconjugate inhibits glioblastoma growth through tumor-microenvironment cross-talk
T Sun, R Patil, A Galstyan, D Klymyshyn, H Ding, A Chesnokova, ...
Cancer research 79 (6), 1239-1251, 2019
812019
Nanobiopolymer for direct targeting and inhibition of EGFR expression in triple negative breast cancer
S Inoue, R Patil, J Portilla-Arias, H Ding, B Konda, A Espinoza, D Mongayt, ...
PLoS One 7 (2), e31070, 2012
782012
Coarse particulate matter (PM2.5–10) in Los Angeles Basin air induces expression of inflammation and cancer biomarkers in rat brains
JY Ljubimova, O Braubach, R Patil, A Chiechi, J Tang, A Galstyan, ...
Scientific reports 8 (1), 5708, 2018
752018
HER2-positive breast cancer targeting and treatment by a peptide-conjugated mini nanodrug
H Ding, PR Gangalum, A Galstyan, I Fox, R Patil, P Hubbard, R Murali, ...
Nanomedicine: Nanotechnology, Biology and Medicine 13 (2), 631-639, 2017
702017
The optimization of polymalic acid peptide copolymers for endosomolytic drug delivery
H Ding, J Portilla-Arias, R Patil, KL Black, JY Ljubimova, E Holler
Biomaterials 32 (22), 5269-5278, 2011
692011
Polymalic acid–based nanobiopolymer provides efficient systemic breast cancer treatment by inhibiting both HER2/neu receptor synthesis and activity
S Inoue, H Ding, J Portilla-Arias, J Hu, B Konda, M Fujita, A Espinoza, ...
Cancer research 71 (4), 1454-1464, 2011
652011
Phosphodiesterase type 5 inhibitors increase Herceptin transport and treatment efficacy in mouse metastatic brain tumor models
J Hu, JY Ljubimova, S Inoue, B Konda, R Patil, H Ding, A Espinoza, ...
PloS one 5 (4), e10108, 2010
622010
Toxicity and efficacy evaluation of multiple targeted polymalic acid conjugates for triple-negative breast cancer treatment
JY Ljubimova, J Portilla-Arias, R Patil, H Ding, S Inoue, JL Markman, ...
Journal of drug targeting 21 (10), 956-967, 2013
592013
Curcumin targeted, polymalic acid‐based MRI contrast agent for the detection of Aβ plaques in Alzheimer's disease
R Patil, PR Gangalum, S Wagner, J Portilla‐Arias, H Ding, ...
Macromolecular bioscience 15 (9), 1212-1217, 2015
562015
Simultaneous blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme
ST Chou, R Patil, A Galstyan, PR Gangalum, WK Cavenee, FB Furnari, ...
Journal of Controlled Release 244, 14-23, 2016
472016
Polymalic acid chlorotoxin nanoconjugate for near-infrared fluorescence guided resection of glioblastoma multiforme
R Patil, A Galstyan, T Sun, ES Shatalova, P Butte, AN Mamelak, C Carico, ...
Biomaterials 206, 146-159, 2019
442019
Distinct mechanisms of membrane permeation induced by two polymalic acid copolymers
H Ding, J Portilla-Arias, R Patil, KL Black, JY Ljubimova, E Holler
Biomaterials 34 (1), 217-225, 2013
352013
Nanoconjugate Platforms Development Based in Poly(β,L‐Malic Acid) Methyl Esters for Tumor Drug Delivery
J Portilla-Arias, R Patil, J Hu, H Ding, KL Black, M García-Alvarez, ...
Journal of Nanomaterials 2010 (1), 825363, 2010
302010
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