Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer’s disease risk factors in yeast S Treusch, S Hamamichi, JL Goodman, KES Matlack, CY Chung, V Baru, ... Science 334 (6060), 1241-1245, 2011 | 451 | 2011 |
Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis S Treusch, S Knuth, SA Slaugenhaupt, E Goldin, BD Grant, H Fares Proceedings of the National Academy of Sciences 101 (13), 4483-4488, 2004 | 278 | 2004 |
High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics M Pellegrino, A Sciambi, S Treusch, R Durruthy-Durruthy, K Gokhale, ... Genome research 28 (9), 1345-1352, 2018 | 221 | 2018 |
Chaperone-dependent amyloid assembly protects cells from prion toxicity PM Douglas*, S Treusch*, HY Ren, R Halfmann, ML Duennwald, ... Proceedings of the National Academy of Sciences 105 (20), 7206, 2008 | 199 | 2008 |
Amyloid deposits: Protection against toxic protein species? S Treusch, DM Cyr, S Lindquist Cell cycle 8 (11), 1668-1674, 2009 | 172 | 2009 |
Genetic interactions contribute less than additive effects to quantitative trait variation in yeast JS Bloom, I Kotenko, MJ Sadhu, S Treusch, FW Albert, L Kruglyak Nature communications 6 (1), 8712, 2015 | 163 | 2015 |
Genetics of single-cell protein abundance variation in large yeast populations FW Albert, S Treusch, AH Shockley, JS Bloom, L Kruglyak Nature 506 (7489), 494-497, 2014 | 147 | 2014 |
Prion induction involves an ancient system for the sequestration of aggregated proteins and heritable changes in prion fragmentation J Tyedmers, S Treusch, J Dong, JM McCaffery, B Bevis, S Lindquist Proceedings of the National Academy of Sciences 107 (19), 8633, 2010 | 146 | 2010 |
Rare variants contribute disproportionately to quantitative trait variation in yeast JS Bloom, J Boocock, S Treusch, MJ Sadhu, L Day, H Oates-Barker, ... Elife 8, e49212, 2019 | 82 | 2019 |
Genetic Mapping of MAPK-Mediated Complex Traits Across S. cerevisiae S Treusch, FW Albert, JS Bloom, IE Kotenko, L Kruglyak PLoS genetics 11 (1), e1004913, 2015 | 64 | 2015 |
Yeast Cells Expressing Amyloid Beta And Uses Therefor S Treusch, KES Matlack, SL Lindquist, WIFORB RESEARCH US Patent 20,130,045,483, 2013 | 58 | 2013 |
An intrinsically disordered yeast prion arrests the cell cycle by sequestering a spindle pole body component S Treusch, S Lindquist Journal of Cell Biology 197 (3), 369-379, 2012 | 58 | 2012 |
Compositions and methods for synthetic gene assembly E Toro, S Treusch, S Chen, WU Cheng-Hsien US Patent 9,677,067, 2017 | 57 | 2017 |
Oligonucleic acid variant libraries and synthesis thereof A Cox, S Treusch, S Chen US Patent 10,844,373, 2020 | 52 | 2020 |
Compositions and methods for synthetic gene assembly E Toro, S Treusch, S Chen, WU Cheng-Hsien US Patent App. 15/433,909, 2017 | 51 | 2017 |
Methods for seamless nucleic acid assembly WU Cheng-Hsien, S Treusch US Patent 11,377,676, 2022 | 32 | 2022 |
Compositions and methods for synthetic gene assembly E Toro, S Treusch, S Chen, WU Cheng-Hsien US Patent App. 17/320,127, 2022 | 20 | 2022 |
Methods for seamless nucleic acid assembly WU Cheng-Hsien, S Treusch US Patent App. 17/825,863, 2022 | 12 | 2022 |
Methods and compositions for emulsification of solid supports in deformable beads AR Sciambi, DJ Eastburn, S Treusch US Patent App. 16/310,336, 2019 | 5 | 2019 |
Single-cell analysis of mutational heterogeneity in acute myeloid leukemia tumors with high-throughput droplet microfluidics DJ Eastburn, M Pellegrino, A Sciambi, S Treusch, L Xu, ... Cancer Research 78 (13_Supplement), 5348-5348, 2018 | 3 | 2018 |