Defining the hallmarks of metastasis DR Welch, DR Hurst Cancer research 79 (12), 3011-3027, 2019 | 698 | 2019 |
Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis DR Hurst, MD Edmonds, GK Scott, CC Benz, KS Vaidya, DR Welch Cancer research 69 (4), 1279-1283, 2009 | 521 | 2009 |
Metastamir: the field of metastasis-regulatory microRNA is spreading DR Hurst, MD Edmonds, DR Welch Cancer research 69 (19), 7495-7498, 2009 | 394 | 2009 |
Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy KT Nash, PA Phadke, JM Navenot, DR Hurst, MA Accavitti-Loper, E Sztul, ... Journal of the National Cancer Institute 99 (4), 309-321, 2007 | 195 | 2007 |
Inhibition of CXCR4 by CTCE-9908 inhibits breast cancer metastasis to lung and bone MM Richert, KS Vaidya, CN Mills, D Wong, W Korz, DR Hurst, DR Welch Oncology reports 21 (3), 761-767, 2009 | 175 | 2009 |
Metastasis suppressor genes: at the interface between the environment and tumor cell growth DR Hurst, DR Welch International review of cell and molecular biology 286, 107-180, 2011 | 161 | 2011 |
Matrix metalloproteinase inhibitors as prospective agents for the prevention and treatment of cardiovascular and neoplastic diseases QXA Sang, Y Jin, RG Newcomer, SC Monroe, X Fang, DR Hurst, S Lee, ... Current topics in medicinal chemistry 6 (4), 289-316, 2006 | 149 | 2006 |
BRMS1 suppresses breast cancer experimental metastasis to multiple organs by inhibiting several steps of the metastatic process PA Phadke, KS Vaidya, KT Nash, DR Hurst, DR Welch The American journal of pathology 172 (3), 809-817, 2008 | 139 | 2008 |
Heparanase-mediated loss of nuclear syndecan-1 enhances histone acetyltransferase (HAT) activity to promote expression of genes that drive an aggressive tumor phenotype A Purushothaman, DR Hurst, C Pisano, S Mizumoto, K Sugahara, ... Journal of Biological Chemistry 286 (35), 30377-30383, 2011 | 131 | 2011 |
Breast cancer metastasis suppressor 1 coordinately regulates metastasis‐associated microRNA expression MD Edmonds, DR Hurst, KS Vaidya, LJ Stafford, D Chen, DR Welch International Journal of Cancer 125 (8), 1778-1785, 2009 | 107 | 2009 |
Gli1 enhances migration and invasion via up-regulation of MMP-11 and promotes metastasis in ERα negative breast cancer cell lines YJ Kwon, DR Hurst, AD Steg, K Yuan, KS Vaidya, DR Welch, AR Frost Clinical & experimental metastasis 28, 437-449, 2011 | 90 | 2011 |
Alterations of BRMS1-ARID4A interaction modify gene expression but still suppress metastasis in human breast cancer cells DR Hurst, Y Xie, KS Vaidya, A Mehta, BP Moore, MA Accavitti-Loper, ... Journal of Biological Chemistry 283 (12), 7438-7444, 2008 | 89 | 2008 |
Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone DR Hurst, A Mehta, BP Moore, PA Phadke, WJ Meehan, MA Accavitti, ... Biochemical and biophysical research communications 348 (4), 1429-1435, 2006 | 84 | 2006 |
Metastasis suppressors and the tumor microenvironment LM Cook, DR Hurst, DR Welch Seminars in cancer biology 21 (2), 113-122, 2011 | 79 | 2011 |
Breast cancer metastasis suppressor-1 differentially modulates growth factor signaling KS Vaidya, S Harihar, PA Phadke, LJ Stafford, DR Hurst, DG Hicks, ... Journal of Biological Chemistry 283 (42), 28354-28360, 2008 | 73 | 2008 |
The intermediate S1′ pocket of the endometase/matrilysin-2 active site revealed by enzyme inhibition kinetic studies, protein sequence analyses, and homology modeling HI Park, Y Jin, DR Hurst, CA Monroe, S Lee, MA Schwartz, QXA Sang Journal of Biological Chemistry 278 (51), 51646-51653, 2003 | 73 | 2003 |
SOCS3 deficiency in myeloid cells promotes tumor development: involvement of STAT3 activation and myeloid-derived suppressor cells H Yu, Y Liu, BC McFarland, JS Deshane, DR Hurst, S Ponnazhagan, ... Cancer immunology research 3 (7), 727-740, 2015 | 70 | 2015 |
Histone deacetylase inhibitors improve the replication of oncolytic herpes simplex virus in breast cancer cells JJ Cody, JM Markert, DR Hurst PloS one 9 (3), e92919, 2014 | 66 | 2014 |
Catalytic-and ecto-domains of membrane type 1-matrix metalloproteinase have similar inhibition profiles but distinct endopeptidase activities DR Hurst, MA Schwartz, MA Ghaffari, Y Jin, H Tschesche, GB Fields, ... Biochemical Journal 377 (3), 775-779, 2004 | 60 | 2004 |
Unraveling the enigmatic complexities of BRMS1-mediated metastasis suppression DR Hurst, DR Welch FEBS letters 585 (20), 3185-3190, 2011 | 52 | 2011 |