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Blaine Mooers
Blaine Mooers
Associate Professor of Biochemistry and Molecular Biology
Dirección de correo verificada de ouhsc.edu - Página principal
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The Holliday junction in an inverted repeat DNA sequence: sequence effects on the structure of four-way junctions
BF Eichman, JM Vargason, BHM Mooers, PS Ho
Proceedings of the National Academy of Sciences 97 (8), 3971-3976, 2000
2902000
The structural basis of myotonic dystrophy from the crystal structure of CUG repeats
BHM Mooers, JS Logue, JA Berglund
Proceedings of the National Academy of Sciences 102 (46), 16626-16631, 2005
2092005
Structural basis of acquired resistance to selpercatinib and pralsetinib mediated by non-gatekeeper RET mutations
V Subbiah, T Shen, SS Terzyan, X Liu, X Hu, KP Patel, M Hu, ...
Annals of Oncology 32 (2), 261-268, 2021
1992021
Shortcuts for faster image creation in PyMOL
BHM Mooers
Protein Science 29 (1), 268-276, 2020
1392020
Precision therapy for RET-altered cancers with RET inhibitors
KZ Thein, V Velcheti, BHM Mooers, J Wu, V Subbiah
Trends in Cancer 7 (12), 1074-1088, 2021
1222021
Novel insights into eukaryotic γ-glutamyltranspeptidase 1 from the crystal structure of the glutamate-bound human enzyme
MB West, Y Chen, S Wickham, A Heroux, K Cahill, MH Hanigan, ...
Journal of Biological Chemistry 288 (44), 31902-31913, 2013
892013
After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial …
J Ding, BHM Mooers, Z Zhang, J Kale, D Falcone, J McNichol, B Huang, ...
Journal of Biological Chemistry 289 (17), 11873-11896, 2014
862014
Repacking the core of T4 lysozyme by automated design
BHM Mooers, D Datta, WA Baase, ES Zollars, SL Mayo, BW Matthews
Journal of Molecular Biology 332 (3), 741-756, 2003
862003
Drug resistance profiles of mutations in the RET kinase domain
J Liu, X., Shen, T., Mooers, B. H., Hilberg, F., & Wu
British Journal of Pharmacology, 2018
822018
The crystal structures of psoralen cross-linked DNAs: drug-dependent formation of Holliday junctions
BF Eichman, BHM Mooers, M Alberti, JE Hearst, PS Ho
Journal of Molecular Biology 308 (1), 15-26, 2001
662001
Human γ-glutamyl transpeptidase 1: Structures of the free enzyme, inhibitor-bound tetrahedral transition states, and glutamate-bound enzyme reveal novel movement within the …
SS Terzyan, AWG Burgett, A Heroux, CA Smith, BHM Mooers, ...
Journal of Biological Chemistry 290 (28), 17576-17586, 2015
612015
Z‐DNA crystallography
PS Ho, BHM Mooers
Biopolymers: Original Research on Biomolecules 44 (1), 65-90, 1997
551997
Simplifying and enhancing the use of PyMOL with horizontal scripts
BHM Mooers
Protein Science 25 (10), 1873-1882, 2016
542016
Alternating and Non-alternating dG-dC Hexanucleotides Crystallize as CanonicalA-DNA
BHM Mooers, GP Schroth, WW Baxter, SP Ho
Journal of molecular biology 249 (4), 772-784, 1995
531995
Structural basis of resistance of mutant RET protein-tyrosine kinase to its inhibitors nintedanib and vandetanib
SS Terzyan, T Shen, X Liu, Q Huang, P Teng, M Zhou, F Hilberg, J Cai, ...
Journal of Biological Chemistry 294 (27), 10428-10437, 2019
502019
Templates for writing PyMOL scripts
BHM Mooers, ME Brown
Protein Science 30 (1), 262-269, 2021
462021
The L730V/I RET roof mutations display different activities toward pralsetinib and selpercatinib
T Shen, X Hu, X Liu, V Subbiah, BHM Mooers, J Wu
NPJ Precision Oncology 5 (1), 48, 2021
442021
Extension to 2268 atoms of direct methods in the ab initio determination of the unknown structure of bacteriophage P22 lysozyme
BHM Mooers, BW Matthews
Biological Crystallography 62 (2), 165-176, 2006
412006
Patient-driven discovery and post-clinical validation of NTRK3 fusion as an acquired resistance mechanism to selpercatinib in RET fusion-positive lung cancer
V Subbiah, T Shen, M Tetzlaff, A Weissferdt, LA Byers, T Cascone, ...
Annals of Oncology 32 (6), 817-819, 2021
402021
Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme
BHM Mooers, WA Baase, JW Wray, BW Matthews
Protein Science 18 (5), 871-880, 2009
392009
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Artículos 1–20