| Global reconstruction of the human metabolic network based on genomic and bibliomic data NC Duarte, SA Becker, N Jamshidi, I Thiele, ML Mo, TD Vo, R Srivas, ... Proceedings of the National Academy of Sciences 104 (6), 1777-1782, 2007 | 1696 | 2007 |
| Genetic control of chromatin states in humans involves local and distal chromosomal interactions F Grubert, JB Zaugg, M Kasowski, O Ursu, DV Spacek, AR Martin, ... Cell 162 (5), 1051-1065, 2015 | 385 | 2015 |
| Disease model of GATA4 mutation reveals transcription factor cooperativity in human cardiogenesis YS Ang, RN Rivas, AJS Ribeiro, R Srivas, J Rivera, NR Stone, K Pratt, ... Cell 167 (7), 1734-1749. e22, 2016 | 279 | 2016 |
| A network of conserved synthetic lethal interactions for exploration of precision cancer therapy R Srivas, JP Shen, CC Yang, SM Sun, J Li, AM Gross, J Jensen, K Licon, ... Molecular cell 63 (3), 514-525, 2016 | 168 | 2016 |
| Landscape of cohesin-mediated chromatin loops in the human genome F Grubert, R Srivas, DV Spacek, M Kasowski, M Ruiz-Velasco, ... Nature 583 (7818), 737-743, 2020 | 167 | 2020 |
| Dissection of DNA damage responses using multiconditional genetic interaction maps A Guénolé, R Srivas, K Vreeken, ZZ Wang, S Wang, NJ Krogan, T Ideker, ... Molecular cell 49 (2), 346-358, 2013 | 113 | 2013 |
| Translation of genotype to phenotype by a hierarchy of cell subsystems MK Yu, M Kramer, J Dutkowski, R Srivas, K Licon, JF Kreisberg, CT Ng, ... Cell systems 2 (2), 77-88, 2016 | 85 | 2016 |
| Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling N Hustedt, A Seeber, R Sack, M Tsai-Pflugfelder, B Bhullar, H Vlaming, ... Molecular cell 57 (2), 273-289, 2015 | 83 | 2015 |
| Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension A Reyes-Palomares, M Gu, F Grubert, I Berest, S Sa, M Kasowski, ... Nature communications 11 (1), 1673, 2020 | 71 | 2020 |
| Genome-wide association data reveal a global map of genetic interactions among protein complexes G Hannum, R Srivas, A Guénolé, H van Attikum, NJ Krogan, RM Karp, ... PLoS genetics 5 (12), e1000782, 2009 | 71 | 2009 |
| Quantitative proteomics reveal ATM kinase-dependent exchange in DNA damage response complexes S Choi, R Srivas, KY Fu, BL Hood, B Dost, GA Gibson, SC Watkins, ... Journal of proteome research 11 (10), 4983-4991, 2012 | 41 | 2012 |
| Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism T van Welsem, T Korthout, R Ekkebus, D Morais, TM Molenaar, ... Nucleic acids research 46 (21), 11251-11261, 2018 | 38 | 2018 |
| Early assessment of molecular progression and response by whole-genome circulating tumor DNA in advanced solid tumors AA Davis, WT Iams, D Chan, MS Oh, RW Lentz, N Peterman, A Robertson, ... Molecular cancer therapeutics 19 (7), 1486-1496, 2020 | 35* | 2020 |
| Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy E Lau, J Sedy, C Sander, M Shaw, Y Feng, M Scortegagna, G Claps, ... Oncogene, 2015 | 33 | 2015 |
| A UV-induced genetic network links the RSC complex to nucleotide excision repair and shows dose-dependent rewiring R Srivas, T Costelloe, AR Carvunis, S Sarkar, E Malta, SM Sun, M Pool, ... Cell reports 5 (6), 1714-1724, 2013 | 31 | 2013 |
| Perspectives on ENCODE F Abascal, R Acosta, NJ Addleman, J Adrian, V Afzal, B Aken, JA Akiyama Nature 583 (7818), 693-699, 2020 | 28 | 2020 |
| Assembling global maps of cellular function through integrative analysis of physical and genetic networks R Srivas, G Hannum, J Ruscheinski, K Ono, PL Wang, M Smoot, T Ideker Nature protocols 6 (9), 1308-1323, 2011 | 24 | 2011 |
| Chemogenetic profiling identifies RAD17 as synthetically lethal with checkpoint kinase inhibition JP Shen, R Srivas, A Gross, J Li, EJ Jaehnig, SM Sun, ... Oncotarget 6 (34), 35755, 2015 | 18 | 2015 |
| Comparison of enzymatic-and bisulfite conversion to map the plasma cell-free methylome in cancer N Lambert, A Robertson, R Srivas, N Peterman, J Close, T Wilson, ... Annals of Oncology 30, v13, 2019 | 4 | 2019 |
| Methods and systems for molecular disease assessment via analysis of circulating tumor dna A Robertson, N Peterman, N Lambert, H Tezcan, R Srivas, P George, ... US Patent App. 17/788,221, 2023 | | 2023 |