Acceso público

Modulation of oxidative stress as an anticancer strategy

C Gorrini, IS Harris, TW Mak

Nature reviews Drug discovery 12 (12), 931-947, 2013

Órdenes: Canadian Institutes of Health Research

Disponibles en algún lugar: 39

[HTML] nature.com

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...

Cell Death & Differentiation 25 (3), 486-541, 2018

Órdenes: US National Institutes of Health, Cancer Research UK, UK Medical Research …

Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression

IS Harris, AE Treloar, S Inoue, M Sasaki, C Gorrini, KC Lee, KY Yung, ...

Cancer cell 27 (2), 211-222, 2015

Órdenes: Canadian Institutes of Health Research, German Research Foundation

[HTML] nih.gov

IDH1 (R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

M Sasaki, CB Knobbe, JC Munger, EF Lind, D Brenner, A Brüstle, ...

Nature 488 (7413), 656-659, 2012

Órdenes: US National Institutes of Health, Canadian Institutes of Health Research …

[PDF] moffitt.org

The complex interplay between antioxidants and ROS in cancer

IS Harris, GM DeNicola

Trends in cell biology 30 (6), 440-451, 2020

Órdenes: US National Institutes of Health

Glutathione primes T cell metabolism for inflammation

TW Mak, M Grusdat, GS Duncan, C Dostert, Y Nonnenmacher, M Cox, ...

Immunity 46 (4), 675-689, 2017

Órdenes: US National Institutes of Health, Canadian Institutes of Health Research …

[PDF] cshlp.org

D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function

M Sasaki, CB Knobbe, M Itsumi, AJ Elia, IS Harris, IIC Chio, RA Cairns, ...

Genes & development 26 (18), 2038-2049, 2012

Órdenes: US National Institutes of Health, Canadian Institutes of Health Research

[HTML] rupress.org

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

C Gorrini, PS Baniasadi, IS Harris, J Silvester, S Inoue, B Snow, PA Joshi, ...

Journal of Experimental Medicine 210 (8), 1529-1544, 2013

Órdenes: Canadian Institutes of Health Research

Differential glutamate metabolism in proliferating and quiescent mammary epithelial cells

JL Coloff, JP Murphy, CR Braun, IS Harris, LM Shelton, K Kami, SP Gygi, ...

Cell metabolism 23 (5), 867-880, 2016

Órdenes: US National Institutes of Health

Non-canonical glutamate-cysteine ligase activity protects against ferroptosis

YP Kang, A Mockabee-Macias, C Jiang, A Falzone, N Prieto-Farigua, ...

Cell metabolism 33 (1), 174-189. e7, 2021

Órdenes: US National Institutes of Health, Florida Department of Health, USA

Cancer cells co-opt the neuronal redox-sensing channel TRPA1 to promote oxidative-stress tolerance

N Takahashi, HY Chen, IS Harris, DG Stover, LM Selfors, RT Bronson, ...

Cancer cell 33 (6), 985-1003. e7, 2018

Órdenes: US National Institutes of Health, Susan G. Komen

[HTML] yevadu.com

Cancer cell metabolism

RA Cairns, I Harris, S McCracken, TW Mak

Cold Spring Harbor symposia on quantitative biology 76, 299-311, 2011

Órdenes: Canadian Institutes of Health Research

Global proteomic assessment of the classical protein-tyrosine phosphatome and “Redoxome”

R Karisch, M Fernandez, P Taylor, C Virtanen, JR St-Germain, LL Jin, ...

Cell 146 (5), 826-840, 2011

Órdenes: US National Institutes of Health, Canadian Institutes of Health Research …

Glutathione restricts serine metabolism to preserve regulatory T cell function

H Kurniawan, DG Franchina, L Guerra, L Bonetti, L Soriano-Baguet, ...

Cell metabolism 31 (5), 920-936. e7, 2020

Órdenes: US National Institutes of Health, Canadian Institutes of Health Research …

Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer

S Shu, HJ Wu, YG Jennifer, R Zeid, IS Harris, B Jovanović, K Murphy, ...

Molecular cell 78 (6), 1096-1113. e8, 2020

Órdenes: US National Institutes of Health, Cancer Research UK, Susan G. Komen

[HTML] cshlp.org

Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15

S Inoue, Z Hao, AJ Elia, D Cescon, L Zhou, J Silvester, B Snow, IS Harris, ...

Genes & development 27 (10), 1101-1114, 2013

Órdenes: Canadian Institutes of Health Research, UK Medical Research Council

Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion

IS Harris, JE Endress, JL Coloff, LM Selfors, SK McBrayer, JM Rosenbluth, ...

Cell metabolism 29 (5), 1166-1181. e6, 2019

Órdenes: US National Institutes of Health, Howard Hughes Medical Institute, Canadian …

3D culture models with CRISPR screens reveal hyperactive NRF2 as a prerequisite for spheroid formation via regulation of proliferation and ferroptosis

N Takahashi, P Cho, LM Selfors, HJ Kuiken, R Kaul, T Fujiwara, IS Harris, ...

Molecular cell 80 (5), 828-844. e6, 2020

Órdenes: US National Institutes of Health

[HTML] cshlp.org

TAp73 depletion accelerates aging through metabolic dysregulation

A Rufini, MV Niklison-Chirou, S Inoue, R Tomasini, IS Harris, A Marino, ...

Genes & development 26 (18), 2009-2014, 2012

Órdenes: Fondazione Telethon, Italy

[HTML] nih.gov