Interactions between β-amyloid and central cholinergic neurons: implications for Alzheimer’s disease S Kar, SPM Slowikowski, D Westaway, HTJ Mount Journal of Psychiatry and Neuroscience 29 (6), 427-441, 2004 | 511 | 2004 |
Amyloid β peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures WH Zheng, S Bastianetto, F Mennicken, W Ma, S Kar Neuroscience 115 (1), 201-211, 2002 | 453 | 2002 |
Glutamate system, amyloid β peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathology TJ Revett, GB Baker, J Jhamandas, S Kar Journal of Psychiatry and Neuroscience 38 (1), 6-23, 2013 | 431 | 2013 |
Insulin-like growth factor I protects and rescues hippocampal neurons against β-amyloid-and human amylin-induced toxicity S Doré, S Kar, R Quirion Proceedings of the National Academy of Sciences 94 (9), 4772-4777, 1997 | 401 | 1997 |
β-Amyloid peptides as direct cholinergic neuromodulators: a missing link? DS Auld, S Kar, R Quirion Trends in neurosciences 21 (1), 43-49, 1998 | 267 | 1998 |
Quantitative autoradiographic localization of [125I] insulin‐like growth factor I,[125I] insulin‐like growth factor II, and [125I] insulin receptor binding sites in developing … S Kar, JG Chabot, R Quirion Journal of Comparative Neurology 333 (3), 375-397, 1993 | 253 | 1993 |
Rediscovering an old friend, IGF-I: potential use in the treatment of neurodegenerative diseases S Doré, S Kar, R Quirion Trends in neurosciences 20 (8), 326-331, 1997 | 244 | 1997 |
Amyloid β‐peptide inhibits high‐affinity choline uptake and acetylcholine release in rat hippocampal slices S Kar, AM Issa, D Seto, DS Auld, B Collier, R Quirion Journal of neurochemistry 70 (5), 2179-2187, 1998 | 221 | 1998 |
Insulin-Like Growth Factor-1–Induced Phosphorylation of Transcription Factor FKHRL1 Is Mediated by Phosphatidylinositol 3-Kinase/Akt Kinase and Role of This Pathway in Insulin … WH Zheng, S Kar, R Quirion Molecular pharmacology 62 (2), 225-233, 2002 | 218 | 2002 |
The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system C Hawkes, S Kar Brain Research Reviews 44 (2-3), 117-140, 2004 | 198 | 2004 |
Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells WH Zheng, S Kar, R Quirion Journal of Biological Chemistry 275 (50), 39152-39158, 2000 | 192 | 2000 |
Memantine protects rat cortical cultured neurons against β‐amyloid‐induced toxicity by attenuating tau phosphorylation MS Song, G Rauw, GB Baker, S Kar European Journal of Neuroscience 28 (10), 1989-2002, 2008 | 171 | 2008 |
Insulin-like growth factor-1 (IGF-1): a neuroprotective trophic factor acting via the Akt kinase pathway WH Zheng, S Kar, S Dore, R Quirion Advances in Research on Neurodegeneration, 261-272, 2000 | 170 | 2000 |
Cyclin-dependent protein kinase 5 primes microtubule-associated protein tau site-specifically for glycogen synthase kinase 3β T Li, C Hawkes, HY Qureshi, S Kar, HK Paudel Biochemistry 45 (10), 3134-3145, 2006 | 169 | 2006 |
Beta-amyloid-related peptides inhibit potassium-evoked acetylcholine release from rat hippocampal slices S Kar, D Seto, P Gaudreau, R Quirion Journal of Neuroscience 16 (3), 1034-1040, 1996 | 167 | 1996 |
Distribution and levels of [125I] IGF-I,[125I] IGF-II and [125I] insulin receptor binding sites in the hippocampus of aged memory-unimpaired and-impaired rats S Dore, S Kar, W Rowe, R Quirion Neuroscience 80 (4), 1033-1040, 1997 | 164 | 1997 |
Internalization of β-amyloid peptide by primary neurons in the absence of apolipoprotein E L Saavedra, A Mohamed, V Ma, S Kar, EP de Chaves Journal of Biological Chemistry 282 (49), 35722-35732, 2007 | 163 | 2007 |
Fucoidan inhibits cellular and neurotoxic effects of β‐amyloid (Aβ) in rat cholinergic basal forebrain neurons JH Jhamandas, MB Wie, K Harris, D MacTavish, S Kar European journal of neuroscience 21 (10), 2649-2659, 2005 | 148 | 2005 |
Role of cholesterol in APP metabolism and its significance in Alzheimer’s disease pathogenesis M Maulik, D Westaway, JH Jhamandas, S Kar Molecular neurobiology 47, 37-63, 2013 | 143 | 2013 |
Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts P De Rossi, V Buggia-Prévot, BLL Clayton, JB Vasquez, C Van Sanford, ... Molecular neurodegeneration 11, 1-21, 2016 | 137 | 2016 |