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Dr. Mukul Jain
Dr. Mukul Jain
President at Zydus Research Centre, Ahmedabad, India
Dirección de correo verificada de zyduscadila.com
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Orexins, a novel family of hypothalamic neuropeptides, modulate pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner.
S Pu, MR Jain, PS Kalra, SP Kalra
Regulatory Peptides 78 (1-3), 133-136, 1998
2821998
Dual PPAR α/γ agonist Saroglitazar improves liver histopathology and biochemistry in experimental NASH models
MR Jain, SR Giri, B Bhoi, C Trivedi, A Rath, R Rathod, R Ranvir, S Kadam, ...
Liver International 38 (6), 1084-1094, 2018
2182018
Interactions between neuropeptide Y and γ-aminobutyric acid in stimulation of feeding: a morphological and pharmacological analysis
S Pu, MR Jain, TL Horvath, S Diano, PS Kalra, SP Kalra
Endocrinology 140 (2), 933-940, 1999
1971999
Prolyl hydroxylase inhibitors: a breakthrough in the therapy of anemia associated with chronic diseases
AA Joharapurkar, VB Pandya, VJ Patel, RC Desai, MR Jain
Journal of medicinal chemistry 61 (16), 6964-6982, 2018
1852018
Evidence that NPY Y1 receptors are involved in stimulation of feeding by orexins (hypocretins) in sated rats
MR Jain, TL Horvath, PS Kalra, SP Kalra
Regulatory peptides 87 (1-3), 19-24, 2000
1852000
Targeted delivery of monoclonal antibody conjugated docetaxel loaded PLGA nanoparticles into EGFR overexpressed lung tumour cells
J Patel, J Amrutiya, P Bhatt, A Javia, M Jain, A Misra
Journal of microencapsulation 35 (2), 204-217, 2018
1752018
Melatonin protects against lipid‐induced mitochondrial dysfunction in hepatocytes and inhibits stellate cell activation during hepatic fibrosis in mice
N Das, A Mandala, S Naaz, S Giri, M Jain, D Bandyopadhyay, RJ Reiter, ...
Journal of pineal research 62 (4), e12404, 2017
1692017
The PPAR α/γ agonist saroglitazar improves insulin resistance and steatohepatitis in a diet induced animal model of nonalcoholic fatty liver disease
DP Kumar, R Caffrey, J Marioneaux, PK Santhekadur, M Bhat, C Alonso, ...
Scientific reports 10 (1), 9330, 2020
1342020
Synthesis and antidiabetic activity of 2, 5-disubstituted-3-imidazol-2-yl-pyrrolo [2, 3-b] pyridines and thieno [2, 3-b] pyridines
RH Bahekar, MR Jain, PA Jadav, VM Prajapati, DN Patel, AA Gupta, ...
Bioorganic & medicinal chemistry 15 (21), 6782-6795, 2007
1312007
Evidence that stimulation of two modalities of pituitary luteinizing hormone release in ovarian steroid-primed ovariectomized rats may involve neuropeptide Y Y1 and Y4 receptors
MR Jain, S Pu, PS Kalra, SP Kalra
Endocrinology 140 (11), 5171-5177, 1999
951999
Pharmacokinetics, safety, and tolerability of saroglitazar (ZYH1), a predominantly PPARα agonist with moderate PPARγ agonist activity in healthy human subjects
RH Jani, K Kansagra, MR Jain, H Patel
Clinical drug investigation 33, 809-816, 2013
932013
Saroglitazar, a novel PPARα/γ agonist with predominant PPARα activity, shows lipid‐lowering and insulin‐sensitizing effects in preclinical models
MR Jain, SR Giri, C Trivedi, B Bhoi, A Rath, G Vanage, P Vyas, R Ranvir, ...
Pharmacology Research & Perspectives 3 (3), e00136, 2015
902015
The anti-gonadotropic effects of cytokines: the role of neuropeptides
PS Kalra, TG Edwards, B Xu, M Jain, SP Kalra
Domestic animal endocrinology 15 (5), 321-332, 1998
901998
Diaryl dihydropyrazole-3-carboxamides with significant in vivo antiobesity activity related to CB1 receptor antagonism: Synthesis, biological evaluation, and molecular modeling …
BK Srivastava, A Joharapurkar, S Raval, JZ Patel, R Soni, P Raval, A Gite, ...
Journal of medicinal chemistry 50 (24), 5951-5966, 2007
832007
Design, synthesis, and biological evaluation of substituted-N-(thieno [2, 3-b] pyridin-3-yl)-guanidines, N-(1H-pyrrolo [2, 3-b] pyridin-3-yl)-guanidines, and N-(1H-indol-3-yl …
RH Bahekar, MR Jain, A Goel, DN Patel, VM Prajapati, AA Gupta, ...
Bioorganic & medicinal chemistry 15 (9), 3248-3265, 2007
812007
Beneficial effects of carbon monoxide-releasing molecule-2 (CORM-2) on acute doxorubicin cardiotoxicity in mice: role of oxidative stress and apoptosis
H Soni, G Pandya, P Patel, A Acharya, M Jain, AA Mehta
Toxicology and applied pharmacology 253 (1), 70-80, 2011
792011
Synthesis and antibacterial activity of 4, 5, 6, 7-tetrahydro-thieno [3, 2-c] pyridine quinolones
BK Srivastava, M Solanki, B Mishra, R Soni, S Jayadev, D Valani, M Jain, ...
Bioorganic & medicinal chemistry letters 17 (7), 1924-1929, 2007
782007
Pathophysiological mechanism of bone loss in type 2 diabetes involves inverse regulation of osteoblast function by PGC-1α and skeletal muscle atrogenes: AdipoR1 as a potential …
MP Khan, AK Singh, AA Joharapurkar, M Yadav, S Shree, H Kumar, ...
Diabetes 64 (7), 2609-2623, 2015
752015
Solvent free synthesis of 1, 5-disubstituted tetrazoles derived from Baylis Hillman acetates as potential TNF-α inhibitors
P Srihari, P Dutta, RS Rao, JS Yadav, S Chandrasekhar, P Thombare, ...
Bioorganic & Medicinal Chemistry Letters 19 (19), 5569-5572, 2009
692009
Effect of GLP-1 based therapies on diabetic dyslipidemia
V J. Patel, A A. Joharapurkar, G B. Shah, M R. Jain
Current diabetes reviews 10 (4), 238-250, 2014
682014
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