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Michael G Roth
Michael G Roth
Professor of Biochemistry, UT Southwestern
Dirección de correo verificada de utsouthwestern.edu
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Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
B Chen, ME Dodge, W Tang, J Lu, Z Ma, CW Fan, S Wei, W Hao, J Kilgore, ...
Nature chemical biology 5 (2), 100-107, 2009
16442009
Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts: many raft proteins are acylated, while few are prenylated
KA Melkonian, AG Ostermeyer, JZ Chen, MG Roth, DA Brown
Journal of Biological Chemistry 274 (6), 3910-3917, 1999
8501999
Interaction of influenza virus haemagglutinin with sphingolipid–cholesterol membrane domains via its transmembrane domain
P Scheiffele, MG Roth, K Simons
The EMBO journal, 1997
8441997
Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi
YJ Wang, J Wang, HQ Sun, M Martinez, YX Sun, E Macia, T Kirchhausen, ...
Cell 114 (3), 299-310, 2003
6452003
Phosphatidylinositol 4, 5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3
AL Rozelle, LM Machesky, M Yamamoto, MHE Driessens, RH Insall, ...
Current Biology 10 (6), 311-320, 2000
6332000
Targeting QseC signaling and virulence for antibiotic development
DA Rasko, CG Moreira, DR Li, NC Reading, JM Ritchie, MK Waldor, ...
Science 321 (5892), 1078-1080, 2008
5972008
Synthetic lethal screen identification of chemosensitizer loci in cancer cells
AW Whitehurst, BO Bodemann, J Cardenas, D Ferguson, L Girard, ...
Nature 446 (7137), 815-819, 2007
5912007
Image-based genome-wide siRNA screen identifies selective autophagy factors
A Orvedahl, R Sumpter Jr, G Xiao, A Ng, Z Zou, Y Tang, M Narimatsu, ...
Nature 480 (7375), 113-117, 2011
5212011
Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles.
NT Ktistakis, HA Brown, MG Waters, PC Sternweis, MG Roth
The Journal of cell biology 134 (2), 295-306, 1996
4831996
Phosphoinositides in constitutive membrane traffic
MG Roth
Physiological reviews 84 (3), 699-730, 2004
3862004
A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin.
CB Brewer, MG Roth
The Journal of cell biology 114 (3), 413-421, 1991
3531991
The liver X receptor ligand T0901317 decreases amyloid β production in vitro and in a mouse model of Alzheimer's disease
RP Koldamova, IM Lefterov, M Staufenbiel, D Wolfe, S Huang, ...
Journal of Biological Chemistry 280 (6), 4079-4088, 2005
3272005
A single amino acid change in the cytoplasmic domain allows the influenza virus hemagglutinin to be endocytosed through coated pits
J Lazarovits, M Roth
Cell 53 (5), 743-752, 1988
2961988
Different biosynthetic transport routes to the plasma membrane in BHK and CHO cells.
T Yoshimori, P Keller, MG Roth, K Simons
The Journal of cell biology 133 (2), 247-256, 1996
2741996
Differential extractability of influenza virus hemagglutinin during intracellular transport in polarized epithelial cells and nonpolar fibroblasts.
JE Skibbens, MG Roth, KS Matlin
The Journal of cell biology 108 (3), 821-832, 1989
2611989
High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase
J Baldwin, CH Michnoff, NA Malmquist, J White, MG Roth, PK Rathod, ...
Journal of Biological Chemistry 280 (23), 21847-21853, 2005
2572005
Mutations in the middle of the transmembrane domain reverse the polarity of transport of the influenza virus hemagglutinin in MDCK epithelial cells
S Lin, HY Naim, A Chapin Rodriguez, MG Roth
The Journal of cell biology 142 (1), 51-57, 1998
2521998
Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A.
NT Ktistakis, HA Brown, PC Sternweis, MG Roth
Proceedings of the National Academy of Sciences 92 (11), 4952-4956, 1995
2491995
Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins.
NT Ktistakis, D Thomas, MG Roth
The Journal of cell biology 111 (4), 1393-1407, 1990
2361990
XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer
J Kim, E McMillan, HS Kim, N Venkateswaran, G Makkar, ...
Nature 538 (7623), 114-117, 2016
2172016
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