Drug targeting to the brain AG De Boer, PJ Gaillard Annu. Rev. Pharmacol. Toxicol. 47 (1), 323-355, 2007 | 473 | 2007 |
Establishment and functional characterization of an in vitro model of the blood–brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes PJ Gaillard, LH Voorwinden, JL Nielsen, A Ivanov, R Atsumi, H Engman, ... European journal of pharmaceutical sciences 12 (3), 215-222, 2001 | 415 | 2001 |
The role of drug transporters at the blood-brain barrier AG De Boer, ICJ Van Der Sandt, PJ Gaillard Annual review of pharmacology and toxicology 43 (1), 629-656, 2003 | 340 | 2003 |
Pharmacokinetics, brain delivery, and efficacy in brain tumor-bearing mice of glutathione pegylated liposomal doxorubicin (2B3-101) PJ Gaillard, CCM Appeldoorn, R Dorland, J Van Kregten, F Manca, ... PloS one 9 (1), e82331, 2014 | 307 | 2014 |
Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation PJ Gaillard, CCM Appeldoorn, J Rip, R Dorland, SMA van der Pol, G Kooij, ... Journal of controlled release 164 (3), 364-369, 2012 | 236 | 2012 |
Relationship between permeability status of the blood–brain barrier and in vitro permeability coefficient of a drug PJ Gaillard, AG de Boer European journal of pharmaceutical sciences 12 (2), 95-102, 2000 | 213 | 2000 |
Targeted delivery across the blood–brain barrier PJ Gaillard, CC Visser, AG de Boer Expert opinion on drug delivery 2 (2), 299-309, 2005 | 195 | 2005 |
Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood–brain barrier in rats J Rip, L Chen, R Hartman, A van den Heuvel, A Reijerkerk, J van Kregten, ... Journal of drug targeting 22 (5), 460-467, 2014 | 193 | 2014 |
Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier PJ Gaillard, ICJ van der Sandt, LH Voorwinden, D Vu, JL Nielsen, ... Pharmaceutical research 17, 1198-1205, 2000 | 180 | 2000 |
Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease M Rotman, MM Welling, A Bunschoten, ME de Backer, J Rip, ... Journal of Controlled Release 203, 40-50, 2015 | 172 | 2015 |
Targeting liposomes with protein drugs to the blood–brain barrier in vitro CC Visser, S Stevanović, LH Voorwinden, L van Bloois, PJ Gaillard, ... European journal of pharmaceutical sciences 25 (2-3), 299-305, 2005 | 153 | 2005 |
Endothelial cell hypertrophy induced by vascular endothelial growth factor in the retina: new insights into the pathogenesis of capillary nonperfusion P Hofman, BC van Blijswijk, PJ Gaillard, GFJM Vrensen, ... Archives of ophthalmology 119 (6), 861-866, 2001 | 152 | 2001 |
Diphtheria toxin receptor-targeted brain drug delivery PJ Gaillard, A Brink, AG De Boer International Congress Series 1277, 185-198, 2005 | 125 | 2005 |
Enhanced doxorubicin delivery to the brain administered through glutathione PEGylated liposomal doxorubicin (2B3-101) as compared with generic Caelyx,®/Doxil®—a cerebral open … T Birngruber, R Raml, W Gladdines, C Gatschelhofer, E Gander, A Ghosh, ... Journal of pharmaceutical sciences 103 (7), 1945-1948, 2014 | 119 | 2014 |
Strategies to improve drug delivery across the blood-brain barrier AG de Boer, PJ Gaillard Clinical pharmacokinetics 46, 553-576, 2007 | 119 | 2007 |
Validation of the Transferrin Receptor for Drug Targeting to Brain Capillary Endothelial Cells In Vitro CC Visser, S Stevanović, L Heleen Voorwinden, PJ Gaillard, ... Journal of drug targeting 12 (3), 145-150, 2004 | 114 | 2004 |
Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration E Vighi, D Trifunović, P Veiga-Crespo, A Rentsch, D Hoffmann, ... Proceedings of the National Academy of Sciences 115 (13), E2997-E3006, 2018 | 113 | 2018 |
Enhanced brain delivery of the opioid peptide DAMGO in glutathione pegylated liposomes: a microdialysis study A Lindqvist, J Rip, PJ Gaillard, S Björkman, M Hammarlund-Udenaes Molecular pharmaceutics 10 (5), 1533-1541, 2013 | 113 | 2013 |
A novel co-culture model of the blood-retinal barrier based on primary retinal endothelial cells, pericytes and astrocytes J Wisniewska-Kruk, KA Hoeben, IMC Vogels, PJ Gaillard, ... Experimental eye research 96 (1), 181-190, 2012 | 113 | 2012 |
Blood–brain barrier dysfunction and recovery AG De Boer, PJ Gaillard Journal of Neural Transmission 113, 455-462, 2006 | 112 | 2006 |