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Aijazuddin Syed
Aijazuddin Syed
Director of Software Engineering (bioinformatics/pathology systems), Memorial Sloan Kettering Cancer
Dirección de correo verificada de mskcc.org
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Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
A Zehir, R Benayed, RH Shah, A Syed, S Middha, HR Kim, P Srinivasan, ...
Nature medicine 23 (6), 703-713, 2017
32542017
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): a hybridization capture-based next-generation sequencing clinical assay for …
DT Cheng, TN Mitchell, A Zehir, RH Shah, R Benayed, A Syed, ...
The Journal of molecular diagnostics 17 (3), 251-264, 2015
19712015
Clinical sequencing defines the genomic landscape of metastatic colorectal cancer
R Yaeger, WK Chatila, MD Lipsyc, JF Hechtman, A Cercek, ...
Cancer cell 33 (1), 125-136. e3, 2018
7672018
Therapy-related clonal hematopoiesis in patients with non-hematologic cancers is common and associated with adverse clinical outcomes
CC Coombs, A Zehir, SM Devlin, A Kishtagari, A Syed, P Jonsson, ...
Cell stem cell 21 (3), 374-382. e4, 2017
7672017
Prospective genomic profiling of prostate cancer across disease states reveals germline and somatic alterations that may affect clinical decision making
W Abida, J Armenia, A Gopalan, R Brennan, M Walsh, D Barron, D Danila, ...
JCO precision oncology 1, 1-16, 2017
5752017
Cancer therapy shapes the fitness landscape of clonal hematopoiesis
KL Bolton, RN Ptashkin, T Gao, L Braunstein, SM Devlin, D Kelly, M Patel, ...
Nature genetics 52 (11), 1219-1226, 2020
5452020
Mutation detection in patients with advanced cancer by universal sequencing of cancer-related genes in tumor and normal DNA vs guideline-based germline testing
D Mandelker, L Zhang, Y Kemel, ZK Stadler, V Joseph, A Zehir, ...
Jama 318 (9), 825-835, 2017
5062017
Genetic determinants of cisplatin resistance in patients with advanced germ cell tumors
A Bagrodia, BH Lee, W Lee, EK Cha, JP Sfakianos, G Iyer, EJ Pietzak, ...
Journal of Clinical Oncology 34 (33), 4000-4007, 2016
1782016
Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing
DT Cheng, M Prasad, Y Chekaluk, R Benayed, J Sadowska, A Zehir, ...
BMC medical genomics 10, 1-9, 2017
1472017
Quantifying the expanding landscape of clinical actionability for patients with cancer
SP Suehnholz, MH Nissan, H Zhang, R Kundra, S Nandakumar, C Lu, ...
Cancer Discovery 14 (1), 49-65, 2024
1132024
Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS
A Rose Brannon, G Jayakumaran, M Diosdado, J Patel, A Razumova, ...
Nature communications 12 (1), 3770, 2021
1072021
Widespread selection for oncogenic mutant allele imbalance in cancer
CM Bielski, MTA Donoghue, M Gadiya, AJ Hanrahan, HH Won, ...
Cancer cell 34 (5), 852-862. e4, 2018
1052018
Development of genome-derived tumor type prediction to inform clinical cancer care
A Penson, N Camacho, Y Zheng, AM Varghese, H Al-Ahmadie, P Razavi, ...
JAMA oncology 6 (1), 84-91, 2020
1002020
The context-specific role of germline pathogenicity in tumorigenesis
P Srinivasan, C Bandlamudi, P Jonsson, Y Kemel, SS Chavan, ...
Nature genetics 53 (11), 1577-1585, 2021
732021
Detection of mutations in myeloid malignancies through paired-sample analysis of microdroplet-PCR deep sequencing data
DT Cheng, J Cheng, TN Mitchell, A Syed, A Zehir, NYT Mensah, ...
The Journal of Molecular Diagnostics 16 (5), 504-518, 2014
292014
Diagnostic yield and clinical relevance of expanded genetic testing for cancer patients
O Ceyhan-Birsoy, G Jayakumaran, Y Kemel, M Misyura, U Aypar, ...
Genome Medicine 14 (1), 92, 2022
252022
Oncologic therapy shapes the fitness landscape of clonal hematopoiesis
KL Bolton, RN Ptashkin, T Gao, L Braunstein, SM Devlin, D Kelly, M Patel, ...
BioRxiv, 848739, 2019
242019
Enhanced specificity of high sensitivity somatic variant profiling in cell-free DNA via paired normal sequencing: design, validation, and clinical experience of the MSK-ACCESS …
AR Brannon, G Jayakumaran, M Diosdado, J Patel, A Razumova, Y Hu, ...
bioRxiv, 2020.06. 27.175471, 2020
232020
Virgibacillus soli sp. nov., isolated from mountain soil
P Kämpfer, AB Arun, HJ Busse, S Langer, CC Young, WM Chen, AA Syed, ...
International Journal of Systematic and EvolutionaryMicrobiology 61 (2), 275-280, 2011
212011
Georgenia soli sp. nov., isolated from iron-ore-contaminated soil in India
P Kämpfer, AB Arun, HJ Busse, S Langer, CC Young, WM Chen, ...
International journal of systematic and evolutionary microbiology 60 (5 …, 2010
192010
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