Dysregulated lipid metabolism and its role in α-synucleinopathy in Parkinson’s disease I Alecu, SAL Bennett Frontiers in neuroscience 13, 444188, 2019 | 224 | 2019 |
1-Deoxysphingolipids HT Lone M, Santos T, Alecu I, Silva L Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019 | 105 | 2019 |
Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction I Alecu, A Tedeschi, N Behler, K Wunderling, C Lamberz, M Lauterbach, ... Journal of Lipid Research, jlr.M068676, 2016 | 98 | 2016 |
HSAN1 mutations in serine palmitoyltransferase reveal a close structure–function–phenotype relationship H Bode, F Bourquin, S Suriyanarayanan, Y Wei, I Alecu, A Othman, ... Human molecular genetics 25 (5), 853-865, 2016 | 92 | 2016 |
Lowering plasma 1-deoxysphingolipids improves neuropathy in diabetic rats A Othman, R Bianchi, I Alecu, Y Wei, C Porretta-Serapiglia, R Lombardi, ... Diabetes 64 (3), 1035-1045, 2015 | 89 | 2015 |
Neurotoxic 1-deoxysphingolipids and paclitaxel-induced peripheral neuropathy R Kramer, J Bielawski, E Kistner-Griffin, A Othman, I Alecu, D Ernst, ... The FASEB Journal 29 (11), 4461-4472, 2015 | 83 | 2015 |
Cytotoxic 1-Deoxysphingolipids Are Metabolized by a Cytochrome P450-Dependent Pathway I Alecu, A Othman, A Penno, E M. Saied, C Arenz, von Eckardstein Arnold, ... Journal of Lipid Research, jlr.M072421, 2016 | 66 | 2016 |
Elevation of plasma 1‐deoxy‐sphingolipids in type 2 diabetes mellitus: a susceptibility to neuropathy? MF Dohrn, A Othman, SK Hirshman, H Bode, I Alecu, E Fähndrich, ... European journal of neurology 22 (5), 806-e55, 2015 | 64 | 2015 |
Altered sphingoid base profiles in type 1 compared to type 2 diabetes N Wei, J Pan, R Pop-Busui, A Othman, I Alecu, T Hornemann, FS Eichler Lipids in health and disease 13, 1-4, 2014 | 47 | 2014 |
Fenofibrate lowers atypical sphingolipids in plasma of dyslipidemic patients: A novel approach for treating diabetic neuropathy? A Othman, R Benghozi, I Alecu, Y Wei, E Niesor, A von Eckardstein, ... Journal of clinical lipidology 9 (4), 568-575, 2015 | 42 | 2015 |
ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase A Zhakupova, N Debeuf, M Krols, W Toussaint, L Vanhoutte, I Alecu, ... The FASEB Journal 30 (12), 4289-4300, 2016 | 33 | 2016 |
Farnesoid X receptor activation induces the degradation of hepatotoxic 1‐deoxysphingolipids in non‐alcoholic fatty liver disease Z Gai, T Gui, I Alecu, MA Lone, T Hornemann, Q Chen, M Visentin, ... Liver International 40 (4), 844-859, 2020 | 30 | 2020 |
Serine palmitoyltransferase assembles at ER–mitochondria contact sites MJ Aaltonen, I Alecu, T König, SAL Bennett, EA Shoubridge Life Science Alliance 5 (2), 2022 | 26 | 2022 |
1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development T Wang, Z Wang, L de Fabritus, J Tao, EM Saied, HJ Lee, BR Ramazanov, ... Developmental Cell 56 (22), 3128-3145. e15, 2021 | 19 | 2021 |
Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity MEH CA Pileggi, DP Blondin, BG Hooks, G Parmar, I Alecu, DA Patten, A ... eBioMedicine, 2022 | 18 | 2022 |
Disturbed sphingolipid metabolism with elevated 1-deoxysphingolipids in glycogen storage disease type I – A link to metabolic control T Hornemanna, I Alecu, N Hagenbuch, A Zhakupova, A Cremonesi, ... Molecular Genetics and Metabolism, 2018 | 14 | 2018 |
Oxidative stress increases 1-deoxysphingolipid levels in chronic kidney disease ZG Ting Gui, Yunlun Li, Shijun Zhang, Irina Alecu, Qingfa Chen, Ying Zhao ... Free Radical Biology and Medicine 164, 139-148, 2021 | 13 | 2021 |
Signed Distance Correlation (SiDCo): an online implementation of distance correlation and partial distance correlation for data-driven network analysis F Monti, D Stewart, A Surendra, I Alecu, T Nguyen-Tran, SAL Bennett, ... Bioinformatics 39 (5), btad210, 2023 | 11 | 2023 |
Plasma Sphingoid Base Profiles of Patients Diagnosed with Intrinsic or Idiosyncratic Drug-induced Liver Injury Z Gai, SL Samodelov, I Alecu, T Hornemann, JI Grove, GP Aithal, ... International Journal of Molecular Sciences 24 (3), 3013, 2023 | 6 | 2023 |
BATL: Bayesian annotations for targeted lipidomics. PTJ Chitpin JG, Surendra A, Nguyen TT, Taylor GP, Xu H, Alecu I, Ortega R ... Bioinformatics, 2021 | 6* | 2021 |