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Guy Alex Ochakovski
Guy Alex Ochakovski
University Eye Clinic, Ludwig-Maximilians- University Munich, Germany
Dirección de correo verificada de med.uni-muenchen.de
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Safety and vision outcomes of subretinal gene therapy targeting cone photoreceptors in achromatopsia: a nonrandomized controlled trial
MD Fischer, S Michalakis, B Wilhelm, D Zobor, R Muehlfriedel, S Kohl, ...
JAMA ophthalmology 138 (6), 643-651, 2020
1622020
AAV8 can induce innate and adaptive immune response in the primate eye
FF Reichel, DL Dauletbekov, R Klein, T Peters, GA Ochakovski, IP Seitz, ...
Molecular Therapy 25 (12), 2648-2660, 2017
1462017
Retinal gene therapy: surgical vector delivery in the translation to clinical trials
GA Ochakovski, KU Bartz-Schmidt, MD Fischer
Frontiers in neuroscience 11, 174, 2017
1132017
Superior retinal gene transfer and biodistribution profile of subretinal versus intravitreal delivery of AAV8 in nonhuman primates
IP Seitz, S Michalakis, B Wilhelm, FF Reichel, GA Ochakovski, E Zrenner, ...
Investigative ophthalmology & visual science 58 (13), 5792-5801, 2017
922017
Efficacy and Safety of Retinal Gene Therapy Using Adeno-Associated Virus Vector for Patients With Choroideremia: A Randomized Clinical Trial.
WB Fischer MD, Ochakovski GA, Beier B, Seitz IP, Vaheb Y, Kortuem C, Reichel ...
JAMA Ophthalmol., 2019
852019
Changes in retinal sensitivity after gene therapy in choroideremia
MD Fischer, GA Ochakovski, B Beier, IP Seitz, Y Vaheb, C Kortuem, ...
Retina 40 (1), 160-168, 2020
632020
Retinal oedema in central retinal artery occlusion develops as a function of time
GA Ochakovski, DA Wenzel, MS Spitzer, S Poli, F Härtig, MD Fischer, ...
Acta Ophthalmologica 98 (6), e680-e684, 2020
332020
High symmetry of visual acuity and visual fields in RPGR-linked retinitis pigmentosa
JS Bellingrath, GA Ochakovski, IP Seitz, S Kohl, E Zrenner, N Hanig, ...
Investigative Ophthalmology & Visual Science 58 (11), 4457-4466, 2017
332017
Disability glare in soft multifocal contact lenses
S Wahl, L Fornoff, GA Ochakovski, A Ohlendorf
Contact Lens and Anterior Eye 41 (2), 175-179, 2018
322018
Subretinal injection for gene therapy does not cause clinically significant outer nuclear layer thinning in normal primate foveae
GA Ochakovski, T Peters, S Michalakis, B Wilhelm, B Wissinger, M Biel, ...
Investigative Ophthalmology & Visual Science 58 (10), 4155-4160, 2017
322017
Safety and toxicology of ocular gene therapy with recombinant AAV vector rAAV. hCNGA3 in nonhuman primates
P Tobias, SI Philipp, M Stylianos, B Martin, W Barbara, R Felix, ...
Human Gene Therapy Clinical Development 30 (2), 50-56, 2019
192019
RD-CURE Consortium AAV8 can induce innate and adaptive immune response in the primate eye
FF Reichel, DL Dauletbekov, R Klein, T Peters, GA Ochakovski, IP Seitz, ...
Mol. Ther 25, 2648-2660, 2017
182017
Symmetric visual response to positive and negative induced spherical defocus under monochromatic light conditions
A Leube, S Kostial, GA Ochakovski, A Ohlendorf, S Wahl
Vision Research 143, 52-57, 2018
112018
Phenotyping of mouse models with OCT
GA Ochakovski, MD Fischer
Retinal Degeneration: Methods and Protocols, 285-291, 2019
72019
Dose-Dependent Progression of Chorioretinal Atrophy at the Injection Site After Subretinal Injection of rAAV2/8 in Nonhuman Primates
IP Seitz, F Wozar, GA Ochakovski, FF Reichel, F Gelisken, ...
Ophthalmology Science 4 (5), 100516, 2024
32024
Effects of subretinal AAV8 gene therapy on microperimetry in CNGA3 achromatopsia patients
GA Ochakovski, A Zhour, L Kuehlewein, S Kohl, A Rindtorff, ...
Investigative Ophthalmology & Visual Science 60 (9), 2921-2921, 2019
32019
Retinal Gene Therapy: Surgical Vector Delivery in the Translation to Clinical Trials. Front Neurosci. 2017; 11: 174
GA Ochakovski, KU Bartz-Schmidt, MD Fischer
2
Evaluation of electroretinography in cynomolgus monkeys after subretinal injection of rAAV. hPDE6A
T Peters, B Wilhelm, S Korte, KU Bartz-Schmidt, S Michalakis, ...
Investigative Ophthalmology & Visual Science 58 (8), 4096-4096, 2017
12017
Ocular Safety and Toxicology of Subretinal Gene Therapy With rAAV. hPDE6A in Nonhuman Primates
IP Seitz, F Wozar, GA Ochakovski, FF Reichel, S Korte, B Korbmacher, ...
Translational Vision Science & Technology 14 (1), 29-29, 2025
2025
Safety study in cynomolgus monkeys after subretinal injection of rAAV. hPDE6A
T Peters, B Wilhelm, B Korbmacher, S Korte, KU Bartz-Schmidt, ...
Investigative Ophthalmology & Visual Science 59 (9), 2658-2658, 2018
2018
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