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Mykola Zdioruk
Mykola Zdioruk
Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School
Dirección de correo verificada de bwh.harvard.edu
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Año
Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis
H Krenzlin, P Behera, V Lorenz, C Passaro, M Zdioruk, MO Nowicki, ...
The Journal of clinical investigation 129 (4), 1671-1683, 2019
792019
LPS induces phosphorylation of actin‐regulatory proteins leading to actin reassembly and macrophage motility
G Kleveta, K Borzęcka, M Zdioruk, M Czerkies, H Kuberczyk, N Sybirna, ...
Journal of cellular biochemistry 113 (1), 80-92, 2012
682012
Tumor interferon signaling is regulated by a lncRNA INCR1 transcribed from the PD-L1 locus
M Mineo, SM Lyons, M Zdioruk, N von Spreckelsen, R Ferrer-Luna, H Ito, ...
Molecular cell 78 (6), 1207-1223. e8, 2020
612020
Plasmodium falciparum erythrocyte membrane protein 1 variants induce cell swelling and disrupt the blood–brain barrier in cerebral malaria
Y Adams, RW Olsen, A Bengtsson, N Dalgaard, M Zdioruk, S Satpathi, ...
Journal of Experimental Medicine 218 (3), e20201266, 2021
592021
Glioblastoma infiltration of both tumor-and virus-antigen specific cytotoxic T cells correlates with experimental virotherapy responses
QA Alayo, H Ito, C Passaro, M Zdioruk, AB Mahmoud, K Grauwet, X Zhang, ...
Scientific reports 10 (1), 5095, 2020
402020
LPS-induced clustering of CD14 triggers generation of PI(4,5)P2
A Płóciennikowska, MI Zdioruk, G Traczyk, A Świątkowska, ...
Journal of cell science 128 (22), 4096-4111, 2015
372015
An interplay between scavenger receptor A and CD14 during activation of J774 cells by high concentrations of LPS
M Czerkies, K Borzęcka, MI Zdioruk, A Płóciennikowska, A Sobota, ...
Immunobiology 218 (10), 1217-1226, 2013
332013
A new inhibitor of tubulin polymerization kills multiple cancer cell types and reveals p21-mediated mechanism determining cell death after mitotic catastrophe
M Zdioruk, A Want, A Mietelska-Porowska, K Laskowska-Kaszub, ...
Cancers 12 (8), 2161, 2020
222020
Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican
N von Spreckelsen, CM Fadzen, N Hartrampf, Y Ghotmi, JM Wolfe, ...
Advanced therapeutics 4 (4), 2000244, 2021
212021
Systemic high-dose dexamethasone treatment may modulate the efficacy of intratumoral viral oncolytic immunotherapy in glioblastoma models
MS Koch, M Zdioruk, MO Nowicki, AM Griffith, E Aguilar, LK Aguilar, ...
Journal for Immunotherapy of Cancer 10 (1), 2022
142022
Familial Alzheimer’s disease lymphocytes respond differently than sporadic cells to oxidative stress: upregulated p53-p21 signaling linked with presenilin 1 mutants
J Wojsiat, K Laskowska-Kaszub, C Alquézar, E Białopiotrowicz, N Esteras, ...
Molecular Neurobiology 54, 5683-5698, 2017
142017
A Pt (IV)-conjugated brain penetrant macrocyclic peptide shows pre-clinical efficacy in glioblastoma
JL Jimenez-Macias, YC Lee, E Miller, T Finkelberg, M Zdioruk, G Berger, ...
Journal of Controlled Release 352, 623-636, 2022
132022
Intratumoral drug-releasing microdevices allow in situ high-throughput pharmaco phenotyping in patients with gliomas
P Peruzzi, C Dominas, G Fell, JD Bernstock, S Blitz, D Mazzetti, M Zdioruk, ...
Science translational medicine 15 (712), eadi0069, 2023
92023
Perturbing DDR signaling enhances cytotoxic effects of local oncolytic virotherapy and modulates the immune environment in glioma
MS Koch, M Zdioruk, MO Nowicki, AM Griffith, E Aguilar-Cordova, ...
Molecular Therapy-Oncolytics 26, 275-288, 2022
92022
Activation of the phosphatidylinositol-3'-kinase pathway with lectin-induced signal through sialo-containing glycoproteins of leukocyte membranes under type 1 diabetes mellitus
NO Sybirna, MI Zdioruk, IV Brodiak, ML Bars' ka, OI Vovk
Ukrains' kyi Biokhimichnyi Zhurnal (1999) 83 (5), 22-31, 2011
72011
A new inhibitor of tubulin polymerization kills multiple cancer cell types and reveals p21-mediated mechanism determining cell death after mitotic catastrophe. Cancers (Basel …
M Zdioruk, A Want, A Mietelska-Porowska, K Laskowska-Kaszub, ...
62020
PPRX-1701, a nanoparticle formulation of 6′-bromoindirubin acetoxime, improves delivery and shows efficacy in preclinical GBM models
M Zdioruk, JL Jimenez-Macias, MO Nowicki, KE Manz, KD Pennell, ...
Cell Reports Medicine 4 (5), 2023
42023
Cytomegalovirus infection of glioblastoma cells leads to NF-κB dependent upregulation of the c-MET oncogenic tyrosine kinase
H Krenzlin, M Zdioruk, MO Nowicki, T Finkelberg, N Keric, ...
Cancer letters 513, 26-35, 2021
42021
Sialic acid-containing glycoproteins are the marker molecules that determine the leukocytes functional state under diabetes mellitus
N Sybirna, I Brodyak, M Zdioruk, M Barska
Sepsis 4 (1), 47-55, 2011
42011
Uncovering transcriptomic landscape alterations of CAN-2409 in in vitro and in vivo glioma models
MS Koch, M Zdioruk, MO Nowicki, MS Hoetker, ZT Herbert, F Barone, ...
Frontiers in Medicine 10, 1140352, 2023
32023
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