Dengue virus activates cGAS through the release of mitochondrial DNA B Sun, KB Sundström, JJ Chew, P Bist, ES Gan, HC Tan, KC Goh, ... Scientific reports 7 (1), 3594, 2017 | 241 | 2017 |
Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-κB activation and cell survival S Ghosh, V Tergaonkar, CV Rothlin, RG Correa, V Bottero, P Bist, ... Cancer cell 10 (3), 215-226, 2006 | 164 | 2006 |
Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4 KA Manu, MK Shanmugam, P Rajendran, F Li, L Ramachandran, HS Hay, ... Molecular cancer 10, 1-14, 2011 | 153 | 2011 |
Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model MK Shanmugam, KA Manu, TH Ong, L Ramachandran, R Surana, P Bist, ... International journal of cancer 129 (7), 1552-1563, 2011 | 153 | 2011 |
Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance SK Biswas, P Bist, MK Dhillon, T Kajiji, C Del Fresno, M Yamamoto, ... The Journal of Immunology 179 (6), 4083-4092, 2007 | 151 | 2007 |
Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells AWL Chua, HS Hay, P Rajendran, MK Shanmugam, F Li, P Bist, ... Biochemical pharmacology 80 (10), 1553-1562, 2010 | 150 | 2010 |
Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-κB: implication in breast cancer metastasis P Bist, SC Leow, QH Phua, S Shu, Q Zhuang, WT Loh, TH Nguyen, ... Oncogene 30 (28), 3174-3185, 2011 | 139 | 2011 |
Bruton’s tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response KG Lee, SSY Kim, L Kui, DCC Voon, M Mauduit, P Bist, X Bi, NA Pereira, ... Cell reports 10 (7), 1055-1065, 2015 | 112 | 2015 |
MRGPR-mediated activation of local mast cells clears cutaneous bacterial infection and protects against reinfection M Arifuzzaman, YR Mobley, HW Choi, P Bist, CA Salinas, ZD Brown, ... Science advances 5 (1), eaav0216, 2019 | 106 | 2019 |
Nutlin-3 inhibits the NFκB pathway in a p53 dependent manner: implications in lung cancer therapy A Dey, ET Wong, P Bist, V Tergaonkar, D Lane Cell cycle 6 (17), 2178-2185, 2007 | 83 | 2007 |
Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response NK Pulloor, S Nair, AD Kostic, P Bist, JD Weaver, AM Riley, R Tyagi, ... PLoS pathogens 10 (2), e1003981, 2014 | 74 | 2014 |
Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma KA Manu, MK Shanmugam, TH Ong, A Subramaniam, KS Siveen, ... PloS one 8 (3), e57015, 2013 | 72 | 2013 |
Intracellular Uropathogenic E. coli Exploits Host Rab35 for Iron Acquisition and Survival within Urinary Bladder Cells N Dikshit, P Bist, SN Fenlon, NK Pulloor, CEL Chua, MA Scidmore, ... PLoS pathogens 11 (8), e1005083, 2015 | 68 | 2015 |
The Nod1, Nod2, and Rip2 axis contributes to host immune defense against intracellular Acinetobacter baumannii infection P Bist, N Dikshit, TH Koh, A Mortellaro, TT Tan, B Sukumaran Infection and immunity 82 (3), 1112-1122, 2014 | 66 | 2014 |
Influenza A virus enhances its propagation through the modulation of Annexin-A1 dependent endosomal trafficking and apoptosis S Arora, W Lim, P Bist, R Perumalsamy, HM Lukman, F Li, LB Welker, ... Cell Death & Differentiation 23 (7), 1243-1256, 2016 | 64 | 2016 |
Annexin‐1‐deficient mice exhibit spontaneous airway hyperresponsiveness and exacerbated allergen‐specific antibody responses in a mouse model of asthma FSP Ng, KY Wong, SP Guan, FB Mustafa, TS Kajiji, P Bist, SK Biswas, ... Clinical & Experimental Allergy 41 (12), 1793-1803, 2011 | 60 | 2011 |
A novel 4, 6-disubstituted-1, 2, 4-triazolo-1, 3, 4-thiadiazole derivative inhibits tumor cell invasion and potentiates the apoptotic effect of TNFα by abrogating NF-κB … R Ningegowda, NS Shivananju, P Rajendran, Basappa, KS Rangappa, ... Apoptosis 22, 145-157, 2017 | 54 | 2017 |
Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-κB and angiogenesis in breast cancer cells D Anbalagan, G Yap, Y Yuan, VK Pandey, WH Lau, S Arora, P Bist, ... PLoS One 9 (12), e114507, 2014 | 46 | 2014 |
Annexin-A1 regulates TLR-mediated IFN-β production through an interaction with TANK-binding kinase 1 P Bist, S Shu, H Lee, S Arora, S Nair, JY Lim, J Dayalan, S Gasser, ... The Journal of Immunology 191 (8), 4375-4382, 2013 | 46 | 2013 |
Collaboration between distinct Rab small GTPase trafficking circuits mediates bacterial clearance from the bladder epithelium Y Miao, P Bist, J Wu, Q Zhao, Q Li, Y Wan, SN Abraham Cell host & microbe 22 (3), 330-342. e4, 2017 | 40 | 2017 |