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Takashi Nakamura
Takashi Nakamura
Faculty of Pharmaceutical Sciences, Hokkaido University
Dirección de correo verificada de pharm.hokudai.ac.jp
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Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma
T Nakamura, H Miyabe, M Hyodo, Y Sato, Y Hayakawa, H Harashima
Journal of controlled release 216, 149-157, 2015
2172015
Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: programmed endosomal escape and dissociation
H Akita, K Kogure, R Moriguchi, Y Nakamura, T Higashi, T Nakamura, ...
Journal of controlled release 143 (3), 311-317, 2010
2002010
STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation
T Nakamura, T Sato, R Endo, S Sasaki, N Takahashi, Y Sato, M Hyodo, ...
Journal for immunotherapy of cancer 9 (7), 2021
1902021
A new adjuvant delivery system ‘cyclic di-GMP/YSK05 liposome’for cancer immunotherapy
H Miyabe, M Hyodo, T Nakamura, Y Sato, Y Hayakawa, H Harashima
Journal of Controlled Release 184, 20-27, 2014
1792014
The effect of size and charge of lipid nanoparticles prepared by microfluidic mixing on their lymph node transitivity and distribution
T Nakamura, M Kawai, Y Sato, M Maeki, M Tokeshi, H Harashima
Molecular pharmaceutics 17 (3), 944-953, 2020
1492020
A lipid nanoparticle for the efficient delivery of siRNA to dendritic cells
S Warashina, T Nakamura, Y Sato, Y Fujiwara, M Hyodo, H Hatakeyama, ...
Journal of controlled release 225, 183-191, 2016
1142016
Efficient MHC class I presentation by controlled intracellular trafficking of antigens in octaarginine-modified liposomes
T Nakamura, R Moriguchi, K Kogure, N Shastri, H Harashima
Molecular Therapy 16 (8), 1507-1514, 2008
1122008
Glycerol monomycolate is a novel ligand for the human, but not mouse macrophage inducible C-type lectin, Mincle
Y Hattori, D Morita, N Fujiwara, D Mori, T Nakamura, H Harashima, ...
Journal of Biological Chemistry 289 (22), 15405-15412, 2014
1002014
The nanoparticulation by octaarginine-modified liposome improves α-galactosylceramide-mediated antitumor therapy via systemic administration
T Nakamura, D Yamazaki, J Yamauchi, H Harashima
Journal of Controlled Release 171 (2), 216-224, 2013
992013
Extrahepatic targeting of lipid nanoparticles in vivo with intracellular targeting for future nanomedicines
T Nakamura, Y Sato, Y Yamada, MM Abd Elwakil, S Kimura, MA Younis, ...
Advanced drug delivery reviews 188, 114417, 2022
932022
Dawn of lipid nanoparticles in lymph node targeting: potential in cancer immunotherapy
T Nakamura, H Harashima
Advanced drug delivery reviews 167, 78-88, 2020
932020
Nanoparticulation of BCG-CWS for application to bladder cancer therapy
T Nakamura, M Fukiage, M Higuchi, A Nakaya, I Yano, J Miyazaki, ...
Journal of controlled release 176, 44-53, 2014
882014
Unique features of a pH‐sensitive fusogenic peptide that improves the transfection efficiency of cationic liposomes
S Futaki, Y Masui, I Nakase, Y Sugiura, T Nakamura, K Kogure, ...
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005
852005
Small-sized, stable lipid nanoparticle for the efficient delivery of siRNA to human immune cell lines
T Nakamura, M Kuroi, Y Fujiwara, S Warashina, Y Sato, H Harashima
Scientific reports 6 (1), 37849, 2016
792016
Effects of vacuum environment on small fatigue crack propagation in Ti–6Al–4V
F Yoshinaka, T Nakamura, K Takaku
International journal of fatigue 91, 29-38, 2016
732016
Noninvasive and efficient transdermal delivery of CpG-oligodeoxynucleotide for cancer immunotherapy
K Kigasawa, K Kajimoto, T Nakamura, S Hama, K Kanamura, ...
Journal of controlled release 150 (3), 256-265, 2011
722011
KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine
SM Shaheen, H Akita, T Nakamura, S Takayama, S Futaki, A Yamashita, ...
Biomaterials 32 (26), 6342-6350, 2011
662011
A KALA-modified lipid nanoparticle containing CpG-free plasmid DNA as a potential DNA vaccine carrier for antigen presentation and as an immune-stimulative adjuvant
N Miura, SM Shaheen, H Akita, T Nakamura, H Harashima
Nucleic acids research 43 (3), 1317-1331, 2015
602015
Multifunctional envelope-type nano device for controlled intracellular trafficking and selective targeting in vivo
K Kajimoto, Y Sato, T Nakamura, Y Yamada, H Harashima
Journal of Controlled Release 190, 593-606, 2014
592014
Reducing the cytotoxicity of lipid nanoparticles associated with a fusogenic cationic lipid in a natural killer cell line by introducing a polycation-based siRNA core
T Nakamura, K Yamada, Y Fujiwara, Y Sato, H Harashima
Molecular pharmaceutics 15 (6), 2142-2150, 2018
572018
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Artículos 1–20