Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma T Nakamura, H Miyabe, M Hyodo, Y Sato, Y Hayakawa, H Harashima Journal of controlled release 216, 149-157, 2015 | 217 | 2015 |
Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: programmed endosomal escape and dissociation H Akita, K Kogure, R Moriguchi, Y Nakamura, T Higashi, T Nakamura, ... Journal of controlled release 143 (3), 311-317, 2010 | 200 | 2010 |
STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation T Nakamura, T Sato, R Endo, S Sasaki, N Takahashi, Y Sato, M Hyodo, ... Journal for immunotherapy of cancer 9 (7), 2021 | 190 | 2021 |
A new adjuvant delivery system ‘cyclic di-GMP/YSK05 liposome’for cancer immunotherapy H Miyabe, M Hyodo, T Nakamura, Y Sato, Y Hayakawa, H Harashima Journal of Controlled Release 184, 20-27, 2014 | 179 | 2014 |
The effect of size and charge of lipid nanoparticles prepared by microfluidic mixing on their lymph node transitivity and distribution T Nakamura, M Kawai, Y Sato, M Maeki, M Tokeshi, H Harashima Molecular pharmaceutics 17 (3), 944-953, 2020 | 149 | 2020 |
A lipid nanoparticle for the efficient delivery of siRNA to dendritic cells S Warashina, T Nakamura, Y Sato, Y Fujiwara, M Hyodo, H Hatakeyama, ... Journal of controlled release 225, 183-191, 2016 | 114 | 2016 |
Efficient MHC class I presentation by controlled intracellular trafficking of antigens in octaarginine-modified liposomes T Nakamura, R Moriguchi, K Kogure, N Shastri, H Harashima Molecular Therapy 16 (8), 1507-1514, 2008 | 112 | 2008 |
Glycerol monomycolate is a novel ligand for the human, but not mouse macrophage inducible C-type lectin, Mincle Y Hattori, D Morita, N Fujiwara, D Mori, T Nakamura, H Harashima, ... Journal of Biological Chemistry 289 (22), 15405-15412, 2014 | 100 | 2014 |
The nanoparticulation by octaarginine-modified liposome improves α-galactosylceramide-mediated antitumor therapy via systemic administration T Nakamura, D Yamazaki, J Yamauchi, H Harashima Journal of Controlled Release 171 (2), 216-224, 2013 | 99 | 2013 |
Extrahepatic targeting of lipid nanoparticles in vivo with intracellular targeting for future nanomedicines T Nakamura, Y Sato, Y Yamada, MM Abd Elwakil, S Kimura, MA Younis, ... Advanced drug delivery reviews 188, 114417, 2022 | 93 | 2022 |
Dawn of lipid nanoparticles in lymph node targeting: potential in cancer immunotherapy T Nakamura, H Harashima Advanced drug delivery reviews 167, 78-88, 2020 | 93 | 2020 |
Nanoparticulation of BCG-CWS for application to bladder cancer therapy T Nakamura, M Fukiage, M Higuchi, A Nakaya, I Yano, J Miyazaki, ... Journal of controlled release 176, 44-53, 2014 | 88 | 2014 |
Unique features of a pH‐sensitive fusogenic peptide that improves the transfection efficiency of cationic liposomes S Futaki, Y Masui, I Nakase, Y Sugiura, T Nakamura, K Kogure, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005 | 85 | 2005 |
Small-sized, stable lipid nanoparticle for the efficient delivery of siRNA to human immune cell lines T Nakamura, M Kuroi, Y Fujiwara, S Warashina, Y Sato, H Harashima Scientific reports 6 (1), 37849, 2016 | 79 | 2016 |
Effects of vacuum environment on small fatigue crack propagation in Ti–6Al–4V F Yoshinaka, T Nakamura, K Takaku International journal of fatigue 91, 29-38, 2016 | 73 | 2016 |
Noninvasive and efficient transdermal delivery of CpG-oligodeoxynucleotide for cancer immunotherapy K Kigasawa, K Kajimoto, T Nakamura, S Hama, K Kanamura, ... Journal of controlled release 150 (3), 256-265, 2011 | 72 | 2011 |
KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine SM Shaheen, H Akita, T Nakamura, S Takayama, S Futaki, A Yamashita, ... Biomaterials 32 (26), 6342-6350, 2011 | 66 | 2011 |
A KALA-modified lipid nanoparticle containing CpG-free plasmid DNA as a potential DNA vaccine carrier for antigen presentation and as an immune-stimulative adjuvant N Miura, SM Shaheen, H Akita, T Nakamura, H Harashima Nucleic acids research 43 (3), 1317-1331, 2015 | 60 | 2015 |
Multifunctional envelope-type nano device for controlled intracellular trafficking and selective targeting in vivo K Kajimoto, Y Sato, T Nakamura, Y Yamada, H Harashima Journal of Controlled Release 190, 593-606, 2014 | 59 | 2014 |
Reducing the cytotoxicity of lipid nanoparticles associated with a fusogenic cationic lipid in a natural killer cell line by introducing a polycation-based siRNA core T Nakamura, K Yamada, Y Fujiwara, Y Sato, H Harashima Molecular pharmaceutics 15 (6), 2142-2150, 2018 | 57 | 2018 |