On the formation and morphology of lipid nanoparticles containing ionizable cationic lipids and siRNA JA Kulkarni, MM Darjuan, JE Mercer, S Chen, R Van Der Meel, ... ACS nano 12 (5), 4787-4795, 2018 | 502 | 2018 |
Influence of polyethylene glycol lipid desorption rates on pharmacokinetics and pharmacodynamics of siRNA lipid nanoparticles BL Mui, YK Tam, M Jayaraman, SM Ansell, X Du, YYC Tam, PJC Lin, ... Molecular Therapy-Nucleic Acids 2, 2013 | 387 | 2013 |
Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA S Chen, YYC Tam, PJC Lin, MMH Sung, YK Tam, PR Cullis Journal of Controlled Release 235, 236-244, 2016 | 337 | 2016 |
Microfluidic mixing: a general method for encapsulating macromolecules in lipid nanoparticle systems AKK Leung, YYC Tam, S Chen, IM Hafez, PR Cullis The Journal of Physical Chemistry B 119 (28), 8698-8706, 2015 | 326 | 2015 |
On the role of helper lipids in lipid nanoparticle formulations of siRNA JA Kulkarni, D Witzigmann, J Leung, YYC Tam, PR Cullis Nanoscale 11 (45), 21733-21739, 2019 | 316 | 2019 |
Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae M Babu, J Vlasblom, S Pu, X Guo, C Graham, BDM Bean, HE Burston, ... Nature 489 (7417), 585-589, 2012 | 284 | 2012 |
Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells G Basha, TI Novobrantseva, N Rosin, YYC Tam, IM Hafez, MK Wong, ... Molecular Therapy 19 (12), 2186-2200, 2011 | 267 | 2011 |
Advances in lipid nanoparticles for siRNA delivery YYC Tam, S Chen, PR Cullis Pharmaceutics 5 (3), 498-507, 2013 | 261 | 2013 |
Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer MS Kostelansky, C Schluter, YYC Tam, S Lee, R Ghirlando, B Beach, ... Cell 129 (3), 485-498, 2007 | 229 | 2007 |
Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae YYC Tam, A Fagarasanu, M Fagarasanu, RA Rachubinski Journal of Biological Chemistry 280 (41), 34933-34939, 2005 | 211 | 2005 |
Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA JA Kulkarni, JL Myhre, S Chen, YYC Tam, A Danescu, JM Richman, ... Nanomedicine: Nanotechnology, Biology and Medicine 13 (4), 1377-1387, 2017 | 210 | 2017 |
Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane M Marelli, JJ Smith, S Jung, E Yi, AI Nesvizhskii, RH Christmas, ... The Journal of cell biology 167 (6), 1099, 2004 | 185 | 2004 |
Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration S Chen, YYC Tam, PJC Lin, AKK Leung, YK Tam, PR Cullis Journal of Controlled Release 196, 106-112, 2014 | 170 | 2014 |
Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo JB Lee, K Zhang, YYC Tam, YK Tam, NM Belliveau, VYC Sung, PJC Lin, ... International Journal of Cancer 131 (5), E781-E790, 2012 | 169 | 2012 |
Lipid nanoparticles for short interfering RNA delivery AKK Leung, YYC Tam, PR Cullis Advances in genetics 88, 71-110, 2014 | 156 | 2014 |
Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiae M Fagarasanu, A Fagarasanu, YYC Tam, JD Aitchison, RA Rachubinski The Journal of cell biology 169 (5), 765-775, 2005 | 139 | 2005 |
Pex11-related Proteins in Peroxisome Dynamics: A Role for the Novel Peroxin Pex27p in Controlling Peroxisome Size and Number in Saccharomyces cerevisiae YYC Tam, JC Torres-Guzman, FJ Vizeacoumar, JJ Smith, M Marelli, ... Molecular biology of the cell 14 (10), 4089-4102, 2003 | 136 | 2003 |
YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae FJ Vizeacoumar, JC Torres-Guzman, YYC Tam, JD Aitchison, ... The Journal of cell biology 161 (2), 321-332, 2003 | 129 | 2003 |
Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads JA Kulkarni, D Witzigmann, J Leung, R van der Meel, J Zaifman, ... Nanoscale 11 (18), 9023-9031, 2019 | 127 | 2019 |
Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA PJC Lin, YYC Tam, I Hafez, A Sandhu, S Chen, MA Ciufolini, IR Nabi, ... Nanomedicine: Nanotechnology, Biology and Medicine 9 (2), 233-246, 2013 | 116 | 2013 |