Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects JE Allen, G Krigsfeld, PA Mayes, L Patel, DT Dicker, AS Patel, NG Dolloff, ... Science translational medicine 5 (171), 171ra17-171ra17, 2013 | 349 | 2013 |
CX3CR1-fractalkine expression regulates cellular mechanisms involved in adhesion, migration, and survival of human prostate cancer cells SA Shulby, NG Dolloff, ME Stearns, O Meucci, A Fatatis Cancer research 64 (14), 4693-4698, 2004 | 244 | 2004 |
CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth NA Warfel, NG Dolloff, DT Dicker, J Malysz, WS El-Deiry Cell cycle 12 (23), 3689-3701, 2013 | 156 | 2013 |
Beyond the CRAB symptoms: a study of presenting clinical manifestations of multiple myeloma G Talamo, U Farooq, M Zangari, J Liao, NG Dolloff, TP Loughran Jr, ... Clinical Lymphoma Myeloma and Leukemia 10 (6), 464-468, 2010 | 134 | 2010 |
Glutaminase inhibitor CB-839 synergizes with carfilzomib in resistant multiple myeloma cells RM Thompson, D Dytfeld, L Reyes, RM Robinson, B Smith, Y Manevich, ... Oncotarget 8 (22), 35863, 2017 | 131 | 2017 |
Bone-metastatic potential of human prostate cancer cells correlates with Akt/PKB activation by α platelet-derived growth factor receptor NG Dolloff, SS Shulby, AV Nelson, ME Stearns, GJ Johannes, JD Thomas, ... Oncogene 24 (45), 6848-6854, 2005 | 94 | 2005 |
Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model HAF Stessman, LB Baughn, A Sarver, T Xia, R Deshpande, A Mansoor, ... Molecular cancer therapeutics 12 (6), 1140-1150, 2013 | 92 | 2013 |
The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth, and chemosensitivity under hypoxic conditions EM Matthew, LS Hart, A Astrinidis, A Navaraj, NG Dolloff, DT Dicker, ... Cell Cycle 8 (24), 4168-4175, 2009 | 84 | 2009 |
Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab LS Hart, NG Dolloff, DT Dicker, C Koumenis, JG Christensen, A Grimberg, ... Cell cycle 10 (14), 2331-2338, 2011 | 73 | 2011 |
ERK and MDM2 prey on FOXO3a W Yang, NG Dolloff, WS El-Deiry nature cell biology 10 (2), 125-126, 2008 | 67 | 2008 |
Design of hydrazide-bearing HDACIs based on panobinostat and their p53 and FLT3-ITD dependency in antileukemia activity X Li, Y Jiang, YK Peterson, T Xu, RA Himes, X Luo, G Yin, ES Inks, ... Journal of medicinal chemistry 63 (10), 5501-5525, 2020 | 58 | 2020 |
Human Bone Marrow Activates the Akt Pathway in Metastatic Prostate Cells through Transactivation of the α-Platelet–Derived Growth Factor Receptor NG Dolloff, MR Russell, N Loizos, A Fatatis Cancer research 67 (2), 555-562, 2007 | 57 | 2007 |
Quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapeutic agents W Wang, JN Gallant, SI Katz, NG Dolloff, CD Smith, J Abdulghani, ... Cancer biology & therapy 12 (3), 229-238, 2011 | 56 | 2011 |
Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma RM Robinson, L Reyes, RM Duncan, H Bian, AB Reitz, Y Manevich, ... Leukemia 33 (4), 1011-1022, 2019 | 54 | 2019 |
The α-receptor for platelet-derived growth factor as a target for antibody-mediated inhibition of skeletal metastases from prostate cancer cells MR Russell, WL Jamieson, NG Dolloff, A Fatatis Oncogene 28 (3), 412-421, 2009 | 49 | 2009 |
Quinacrine synergizes with 5-fluorouracil and other therapies in colorectal cancer JN Gallant, JE Allen, CD Smith, DT Dicker, W Wang, NG Dolloff, A Navaraj, ... Cancer biology & therapy 12 (3), 239-251, 2011 | 47 | 2011 |
Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation NG Dolloff, PA Mayes, LS Hart, DT Dicker, R Humphreys, WS El-Deiry Science translational medicine 3 (86), 86ra50-86ra50, 2011 | 45 | 2011 |
Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1 PA Mayes, NG Dolloff, CJ Daniel, JJ Liu, LS Hart, K Kuribayashi, JE Allen, ... Cancer research 71 (15), 5265-5275, 2011 | 37 | 2011 |
Targeted therapy of multiple myeloma NG Dolloff, G Talamo Impact of Genetic Targets on Cancer Therapy, 197-221, 2013 | 33 | 2013 |
Prozone effect of serum IgE levels in a case of plasma cell leukemia G Talamo, W Castellani, NG Dolloff Journal of hematology & oncology 3, 1-3, 2010 | 30 | 2010 |