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Francesca M Spagnoli
Francesca M Spagnoli
Group Leader, Center for Stem Cells and Regenerative Medicine, King's College London, UK
Dirección de correo verificada de kcl.ac.uk
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Balancing BMP signaling through integrated inputs into the Smad1 linker
G Sapkota, C Alarcón, FM Spagnoli, AH Brivanlou, J Massagué
Molecular cell 25 (3), 441-454, 2007
4882007
The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection
A Rosa, FM Spagnoli, AH Brivanlou
Developmental cell 16 (4), 517-527, 2009
2622009
Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes
L Amicone, FM Spagnoli, G Späth, S Giordano, C Tommasini, ...
The EMBO journal, 1997
1941997
Mechanisms, hallmarks, and implications of stem cell quiescence
IJ Cho, PPW Lui, J Obajdin, F Riccio, W Stroukov, TL Willis, F Spagnoli, ...
Stem cell reports 12 (6), 1190-1200, 2019
1482019
In vivo reprogramming for tissue repair
C Heinrich, FM Spagnoli, B Berninger
Nature cell biology 17 (3), 204-211, 2015
1102015
Snail controls differentiation of hepatocytes by repressing HNF4α expression
C Cicchini, D Filippini, S Coen, A Marchetti, C Cavallari, I Laudadio, ...
Journal of cellular physiology 209 (1), 230-238, 2006
1022006
Identification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liver
FM Spagnoli, L Amicone, M Tripodi, MC Weiss
The Journal of cell biology 143 (4), 1101-1112, 1998
971998
Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence
E Rodríguez-Seguel, N Mah, H Naumann, IM Pongrac, N Cerdá-Esteban, ...
Genes & Development 27 (17), 1932-1946, 2013
962013
Inhibition of MMH (Met murine hepatocyte) cell differentiation by TGFβ is abrogated by pre-treatment with the heritable differentiation effector FGF1
FM Spagnoli, C Cicchini, M Tripodi, MC Weiss
Journal of Cell Science 113 (20), 3639-3647, 2000
882000
Recessive mutations in PCBD1 cause a new type of early-onset diabetes
D Simaite, J Kofent, M Gong, F Rüschendorf, S Jia, P Arn, K Bentler, ...
Diabetes 63 (10), 3557-3564, 2014
642014
The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm
FM Spagnoli, AH Brivanlou
Oxford University Press for The Company of Biologists Limited 135 (3), 451-461, 2008
612008
Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2
N Cerdá-Esteban, H Naumann, S Ruzittu, N Mah, IM Pongrac, ...
Nature communications 8 (1), 14127, 2017
522017
Guiding embryonic stem cells towards differentiation: lessons from molecular embryology
FM Spagnoli, A Hemmati-Brivanlou
Current opinion in genetics & development 16 (5), 469-475, 2006
492006
Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas
KM Petzold, H Naumann, FM Spagnoli
Development 140 (1), 126-135, 2013
442013
A specialized niche in the pancreatic microenvironment promotes endocrine differentiation
C Cozzitorto, L Mueller, S Ruzittu, N Mah, D Willnow, JF Darrigrand, ...
Developmental cell 55 (2), 150-162. e6, 2020
432020
Employing core regulatory circuits to define cell identity
N Almeida, MWH Chung, EM Drudi, EN Engquist, E Hamrud, A Isaacson, ...
The EMBO journal 40 (10), e106785, 2021
422021
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes
H Zhu, G Wang, KV Nguyen-Ngoc, D Kim, M Miller, G Goss, J Kovsky, ...
Developmental cell 58 (9), 727-743. e11, 2023
412023
From endoderm to pancreas: a multistep journey
FM Spagnoli
Cellular and Molecular Life Sciences 64, 2378-2390, 2007
412007
Glimpse into Hox and tale regulation of cell differentiation and reprogramming
N Cerdá‐Esteban, FM Spagnoli
Developmental Dynamics 243 (1), 76-87, 2014
402014
A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development
CSM Helker, ST Mullapudi, LM Mueller, J Preussner, S Tunaru, O Skog, ...
Development 146 (14), dev172569, 2019
392019
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Artículos 1–20