Balancing BMP signaling through integrated inputs into the Smad1 linker G Sapkota, C Alarcón, FM Spagnoli, AH Brivanlou, J Massagué Molecular cell 25 (3), 441-454, 2007 | 488 | 2007 |
The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection A Rosa, FM Spagnoli, AH Brivanlou Developmental cell 16 (4), 517-527, 2009 | 262 | 2009 |
Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes L Amicone, FM Spagnoli, G Späth, S Giordano, C Tommasini, ... The EMBO journal, 1997 | 194 | 1997 |
Mechanisms, hallmarks, and implications of stem cell quiescence IJ Cho, PPW Lui, J Obajdin, F Riccio, W Stroukov, TL Willis, F Spagnoli, ... Stem cell reports 12 (6), 1190-1200, 2019 | 148 | 2019 |
In vivo reprogramming for tissue repair C Heinrich, FM Spagnoli, B Berninger Nature cell biology 17 (3), 204-211, 2015 | 110 | 2015 |
Snail controls differentiation of hepatocytes by repressing HNF4α expression C Cicchini, D Filippini, S Coen, A Marchetti, C Cavallari, I Laudadio, ... Journal of cellular physiology 209 (1), 230-238, 2006 | 102 | 2006 |
Identification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liver FM Spagnoli, L Amicone, M Tripodi, MC Weiss The Journal of cell biology 143 (4), 1101-1112, 1998 | 97 | 1998 |
Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence E Rodríguez-Seguel, N Mah, H Naumann, IM Pongrac, N Cerdá-Esteban, ... Genes & Development 27 (17), 1932-1946, 2013 | 96 | 2013 |
Inhibition of MMH (Met murine hepatocyte) cell differentiation by TGFβ is abrogated by pre-treatment with the heritable differentiation effector FGF1 FM Spagnoli, C Cicchini, M Tripodi, MC Weiss Journal of Cell Science 113 (20), 3639-3647, 2000 | 88 | 2000 |
Recessive mutations in PCBD1 cause a new type of early-onset diabetes D Simaite, J Kofent, M Gong, F Rüschendorf, S Jia, P Arn, K Bentler, ... Diabetes 63 (10), 3557-3564, 2014 | 64 | 2014 |
The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm FM Spagnoli, AH Brivanlou Oxford University Press for The Company of Biologists Limited 135 (3), 451-461, 2008 | 61 | 2008 |
Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2 N Cerdá-Esteban, H Naumann, S Ruzittu, N Mah, IM Pongrac, ... Nature communications 8 (1), 14127, 2017 | 52 | 2017 |
Guiding embryonic stem cells towards differentiation: lessons from molecular embryology FM Spagnoli, A Hemmati-Brivanlou Current opinion in genetics & development 16 (5), 469-475, 2006 | 49 | 2006 |
Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas KM Petzold, H Naumann, FM Spagnoli Development 140 (1), 126-135, 2013 | 44 | 2013 |
A specialized niche in the pancreatic microenvironment promotes endocrine differentiation C Cozzitorto, L Mueller, S Ruzittu, N Mah, D Willnow, JF Darrigrand, ... Developmental cell 55 (2), 150-162. e6, 2020 | 43 | 2020 |
Employing core regulatory circuits to define cell identity N Almeida, MWH Chung, EM Drudi, EN Engquist, E Hamrud, A Isaacson, ... The EMBO journal 40 (10), e106785, 2021 | 42 | 2021 |
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes H Zhu, G Wang, KV Nguyen-Ngoc, D Kim, M Miller, G Goss, J Kovsky, ... Developmental cell 58 (9), 727-743. e11, 2023 | 41 | 2023 |
From endoderm to pancreas: a multistep journey FM Spagnoli Cellular and Molecular Life Sciences 64, 2378-2390, 2007 | 41 | 2007 |
Glimpse into Hox and tale regulation of cell differentiation and reprogramming N Cerdá‐Esteban, FM Spagnoli Developmental Dynamics 243 (1), 76-87, 2014 | 40 | 2014 |
A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development CSM Helker, ST Mullapudi, LM Mueller, J Preussner, S Tunaru, O Skog, ... Development 146 (14), dev172569, 2019 | 39 | 2019 |