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Chad M. Thompson
Chad M. Thompson
ToxStrategies
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Evaluation of physiologically based pharmacokinetic models for use in risk assessment
WA Chiu, HA Barton, RS DeWoskin, P Schlosser, CM Thompson, ...
Journal of applied toxicology 27 (3), 218-237, 2007
1652007
Assessment of the mode of action for hexavalent chromium-induced lung cancer following inhalation exposures
DM Proctor, M Suh, SL Campleman, CM Thompson
Toxicology 325, 160-179, 2014
1522014
Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment
GE Johnson, LG Soeteman‐Hernández, BB Gollapudi, OG Bodger, ...
Environmental and molecular mutagenesis, 2014
1402014
A chronic oral reference dose for hexavalent chromium‐induced intestinal cancer
CM Thompson, CR Kirman, DM Proctor, LC Haws, M Suh, SM Hays, ...
Journal of Applied Toxicology 34 (5), 525-536, 2014
1352014
Activation of G-proteins by morphine and codeine congeners: insights to the relevance of O-and N-demethylated metabolites at μ-and δ-opioid receptors
CM Thompson, H Wojno, E Greiner, EL May, KC Rice, DE Selley
Journal of Pharmacology and Experimental Therapeutics 308 (2), 547-554, 2004
1142004
Database for physiologically based pharmacokinetic (PBPK) modeling: physiological data for healthy and health-impaired elderly
CM Thompson, DO Johns, B Sonawane, HA Barton, D Hattis, R Tardif, ...
Journal of Toxicology and Environmental Health, Part B 12 (1), 1-24, 2009
1122009
Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans
CM Thompson, DM Proctor, M Suh, LC Haws, CR Kirman, MA Harris
Critical reviews in toxicology 43 (3), 244-274, 2013
992013
Investigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium
CM Thompson, DM Proctor, LC Haws, CD Hébert, SD Grimes, ...
Toxicological Sciences 123 (1), 58-70, 2011
962011
Protein Expression, Characterization, and Regulation ofCYP4F4andCYP4F5Cloned from Rat Brain
H Kawashima, E Kusunose, CM Thompson, HW Strobel
Archives of biochemistry and biophysics 347 (1), 148-154, 1997
931997
Application of the US EPA mode of action Framework for purposes of guiding future research: a case study involving the oral carcinogenicity of hexavalent chromium
CM Thompson, LC Haws, MA Harris, NM Gatto, DM Proctor
Toxicological Sciences 119 (1), 20-40, 2011
912011
Cytochromes P450 in brain: function and significance
HW Strobel, CM Thompson, L Antonovic
Current drug metabolism 2 (2), 199-214, 2001
882001
Assessment of Cr (VI)-Induced Cytotoxicity and Genotoxicity Using High Content Analysis
CM Thompson, Y Fedorov, DD Brown, M Suh, DM Proctor, L Kuriakose, ...
PLoS ONE 7 (8), e42720, 2012
822012
The vesicle transport protein Vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner
B Gerhardt, TJ Kordas, CM Thompson, P Patel, T Vida
Journal of Biological Chemistry 273 (25), 15818-15829, 1998
801998
Recombinant cytochrome P450 2D18 metabolism of dopamine and arachidonic acid
CM Thompson, JH Capdevila, HW Strobel
Journal of Pharmacology and Experimental Therapeutics 294 (3), 1120-1130, 2000
792000
Approaches for applications of physiologically based pharmacokinetic models in risk assessment
CM Thompson, B Sonawane, HA Barton, RS DeWoskin, JC Lipscomb, ...
Journal of Toxicology and Environmental Health, Part B 11 (7), 519-547, 2008
662008
Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes …
CM Thompson, DM Proctor, M Suh, LC Haws, CD Hébert, JF Mann, ...
Toxicological Sciences 125 (1), 79-90, 2012
642012
Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment
VS Wilson, N Keshava, S Hester, D Segal, W Chiu, CM Thompson, ...
Toxicology and applied pharmacology 271 (3), 299-308, 2013
632013
Renal clearance parameters for PBPK model analysis of early lifestage differences in the disposition of environmental toxicants
RS DeWoskin, CM Thompson
Regulatory Toxicology and Pharmacology 51 (1), 66-86, 2008
612008
Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90days of exposure to hexavalent chromium in drinking water
AK Kopec, S Kim, AL Forgacs, TR Zacharewski, DM Proctor, MA Harris, ...
Toxicology and applied pharmacology 259 (1), 13-26, 2012
602012
Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium
CR Kirman, SM Hays, LL Aylward, M Suh, MA Harris, CM Thompson, ...
Chemico-biological interactions 200 (1), 45-64, 2012
582012
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Artículos 1–20