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Artak Tovmasyan
Artak Tovmasyan
Senior Research Associate, Duke University
Dirección de correo verificada de duke.edu - Página principal
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Manganese superoxide dismutase, MnSOD and its mimics
S Miriyala, I Spasojevic, A Tovmasyan, D Salvemini, Z Vujaskovic, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (5), 794-814, 2012
4552012
SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways
I Batinic-Haberle, A Tovmasyan, ERH Roberts, Z Vujaskovic, KW Leong, ...
Antioxidants & redox signaling 20 (15), 2372-2415, 2014
2482014
An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins–from superoxide dismutation to H2O2-driven pathways
I Batinic-Haberle, A Tovmasyan, I Spasojevic
Redox biology 5, 43-65, 2015
1722015
Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics
I Batinic-Haberle, Z Rajic, A Tovmasyan, JS Reboucas, X Ye, KW Leong, ...
Free Radical Biology and Medicine 51 (5), 1035-1053, 2011
1612011
Mn porphyrin-based redox-active drugs: differential effects as cancer therapeutics and protectors of normal tissue against oxidative injury
I Batinic-Haberle, A Tovmasyan, I Spasojevic
Antioxidants & Redox Signaling 29 (16), 1691-1724, 2018
1382018
Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities
I Batinic-Haberle, I Spasojevic, HM Tse, A Tovmasyan, Z Rajic, ...
Amino acids 42, 95-113, 2012
1242012
Effect of molecular characteristics on cellular uptake, subcellular localization, and phototoxicity of Zn (II) N-alkylpyridylporphyrins
R Ezzeddine, A Al-Banaw, A Tovmasyan, JD Craik, I Batinic-Haberle, ...
Journal of Biological Chemistry 288 (51), 36579-36588, 2013
1082013
Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators
A Tovmasyan, H Sheng, T Weitner, A Arulpragasam, M Lu, DS Warner, ...
Medical Principles and Practice 22 (2), 103-130, 2013
1012013
A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics
A Tovmasyan, CGC Maia, T Weitner, S Carballal, RS Sampaio, D Lieb, ...
Free Radical Biology and Medicine 86, 308-321, 2015
962015
A new SOD mimic, Mn (III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity
Z Rajic, A Tovmasyan, I Spasojevic, H Sheng, M Lu, AM Li, EB Gralla, ...
Free Radical Biology and Medicine 52 (9), 1828-1834, 2012
962012
Novel manganese-porphyrin superoxide dismutase-mimetic widens the therapeutic margin in a preclinical head and neck cancer model
KA Ashcraft, MK Boss, A Tovmasyan, KR Choudhury, AN Fontanella, ...
International Journal of Radiation Oncology* Biology* Physics 93 (4), 892-900, 2015
862015
Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death
MK Evans, A Tovmasyan, I Batinic-Haberle, GR Devi
Free Radical Biology and Medicine 68, 302-314, 2014
832014
Anticancer therapeutic potential of Mn porphyrin/ascorbate system
A Tovmasyan, RS Sampaio, MK Boss, JC Bueno-Janice, BH Bader, ...
Free Radical Biology and Medicine 89, 1231-1247, 2015
802015
Radioprotection of the Brain White Matter by Mn(III) N-Butoxyethylpyridylporphyrin–Based Superoxide Dismutase Mimic MnTnBuOE-2-PyP5+
DH Weitzel, A Tovmasyan, KA Ashcraft, Z Rajic, T Weitner, C Liu, W Li, ...
Molecular cancer therapeutics 14 (1), 70-79, 2015
792015
Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology
A Tovmasyan, T Weitner, H Sheng, MM Lu, Z Rajic, DS Warner, ...
Inorganic chemistry 52 (10), 5677-5691, 2013
782013
Important cellular targets for antimicrobial photodynamic therapy
MM Awad, A Tovmasyan, JD Craik, I Batinic-Haberle, LT Benov
Applied microbiology and biotechnology 100, 7679-7688, 2016
702016
Novel role of 4-hydroxy-2-nonenal in AIFm2-mediated mitochondrial stress signaling
S Miriyala, C Thippakorn, L Chaiswing, Y Xu, T Noel, A Tovmasyan, ...
Free Radical Biology and Medicine 91, 68-80, 2016
682016
Simple biological systems for assessing the activity of superoxide dismutase mimics
A Tovmasyan, JS Reboucas, L Benov
Antioxidants & Redox Signaling 20 (15), 2416-2436, 2014
682014
Sublethal photodynamic treatment does not lead to development of resistance
R Al-Mutairi, A Tovmasyan, I Batinic-Haberle, L Benov
Frontiers in microbiology 9, 1699, 2018
652018
Optimizing Zn porphyrin-based photosensitizers for efficient antibacterial photodynamic therapy
K Alenezi, A Tovmasyan, I Batinic-Haberle, LT Benov
Photodiagnosis and photodynamic therapy 17, 154-159, 2017
642017
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Artículos 1–20