| Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation N Voigt, J Heijman, Q Wang, DY Chiang, N Li, M Karck, XHT Wehrens, ... Circulation 129 (2), 145-156, 2014 | 550 | 2014 |
| Ryanodine receptor–mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model N Li, DY Chiang, S Wang, Q Wang, L Sun, N Voigt, JL Respress, S Ather, ... Circulation 129 (12), 1276-1285, 2014 | 200 | 2014 |
| Junctophilin-2 is necessary for T-tubule maturation during mouse heart development JO Reynolds, DY Chiang, W Wang, DL Beavers, SS Dixit, DG Skapura, ... Cardiovascular research 100 (1), 44-53, 2013 | 128 | 2013 |
| Loss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release DY Chiang, N Kongchan, DL Beavers, KM Alsina, N Voigt, JR Neilson, ... Circulation: Arrhythmia and Electrophysiology 7 (6), 1214-1222, 2014 | 124 | 2014 |
| Regulatory T cell dysfunction in subjects with common variable immunodeficiency complicated by autoimmune disease PY Grace, D Chiang, SJ Song, EG Hoyte, J Huang, C Vanishsarn, ... Clinical immunology 131 (2), 240-253, 2009 | 116 | 2009 |
| SPEG (striated muscle preferentially expressed protein kinase) is essential for cardiac function by regulating junctional membrane complex activity AP Quick, Q Wang, LE Philippen, G Barreto-Torres, DY Chiang, ... Circulation research 120 (1), 110-119, 2017 | 103 | 2017 |
| Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility J Barc, R Tadros, C Glinge, DY Chiang, M Jouni, F Simonet, SJ Jurgens, ... Nature genetics 54 (3), 232-239, 2022 | 101 | 2022 |
| Emerging roles of junctophilin-2 in the heart and implications for cardiac diseases DL Beavers, AP Landstrom, DY Chiang, XHT Wehrens Cardiovascular research 103 (2), 198-205, 2014 | 100 | 2014 |
| Loss of SPEG inhibitory phosphorylation of ryanodine receptor type-2 promotes atrial fibrillation HM Campbell, AP Quick, I Abu-Taha, DY Chiang, CF Kramm, TA Word, ... Circulation 142 (12), 1159-1172, 2020 | 70 | 2020 |
| Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation DY Chiang, N Li, Q Wang, KM Alsina, AP Quick, JO Reynolds, G Wang, ... Cardiovascular research 103 (1), 178-187, 2014 | 69 | 2014 |
| Identification of microRNA–mRNA dysregulations in paroxysmal atrial fibrillation DY Chiang, M Zhang, N Voigt, KM Alsina, H Jakob, JF Martin, D Dobrev, ... International Journal of Cardiology 184, 190-197, 2015 | 63 | 2015 |
| Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance SS Dixit, T Wang, EJQ Manzano, S Yoo, J Lee, DY Chiang, N Ryan, ... PloS one 8 (3), e58655, 2013 | 62 | 2013 |
| Loss of protein phosphatase 1 regulatory subunit PPP1R3A promotes atrial fibrillation KM Alsina, M Hulsurkar, S Brandenburg, D Kownatzki-Danger, C Lenz, ... Circulation 140 (8), 681-693, 2019 | 60 | 2019 |
| Relation of cardiac dysfunction to rhythm abnormalities in patients with Duchenne or Becker muscular dystrophies DY Chiang, HD Allen, JJ Kim, SO Valdes, Y Wang, RH Pignatelli, ... The American Journal of Cardiology 117 (8), 1349-1354, 2016 | 55 | 2016 |
| CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome S DeGrande, D Nixon, O Koval, JW Curran, P Wright, Q Wang, F Kashef, ... Heart Rhythm 9 (12), 2034-2041, 2012 | 53 | 2012 |
| Oxidized CaMKII (Ca2+/Calmodulin-Dependent Protein Kinase II) Is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy Q Wang, AP Quick, S Cao, J Reynolds, DY Chiang, D Beavers, N Li, ... Circulation: Arrhythmia and Electrophysiology 11 (4), e005682, 2018 | 51 | 2018 |
| Expression and function of Kv1. 1 potassium channels in human atria from patients with atrial fibrillation E Glasscock, N Voigt, MD McCauley, Q Sun, N Li, DY Chiang, XB Zhou, ... Basic research in cardiology 110, 1-15, 2015 | 45 | 2015 |
| Alterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients DY Chiang, N Lebesgue, DL Beavers, KM Alsina, JMA Damen, N Voigt, ... Journal of the American College of Cardiology 65 (2), 163-173, 2015 | 45 | 2015 |
| Genetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling X Yang, T Wang, X Lin, X Yue, Q Wang, G Wang, Q Fu, X Ai, DY Chiang, ... Circulation research 116 (1), e1-e10, 2015 | 38 | 2015 |
| Regulating the regulator: insights into the cardiac protein phosphatase 1 interactome DY Chiang, AJR Heck, D Dobrev, XHT Wehrens Journal of molecular and cellular cardiology 101, 165-172, 2016 | 36 | 2016 |
Xander Wehrens, MD PhDDirector, Cardiovascular Research Institute, Baylor College of MedicineDirección de correo verificada de bcm.edu