Human IL6 enhances leptin action in mice M Sadagurski, L Norquay, J Farhang, K D’Aquino, K Copps, MF White Diabetologia 53, 525-535, 2010 | 184 | 2010 |
Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation M Sadagurski, S Yakar, G Weingarten, M Holzenberger, CJ Rhodes, ... Molecular and cellular biology 26 (7), 2675-2687, 2006 | 155 | 2006 |
IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease M Sadagurski, Z Cheng, A Rozzo, I Palazzolo, GR Kelley, X Dong, ... The Journal of clinical investigation 121 (10), 4070-4081, 2011 | 118 | 2011 |
Anti‐aging drugs reduce hypothalamic inflammation in a sex‐specific manner M Sadagurski, G Cady, RA Miller Aging Cell 16 (4), 652-660, 2017 | 81 | 2017 |
Growth hormone modulates hypothalamic inflammation in long‐lived pituitary dwarf mice M Sadagurski, T Landeryou, G Cady, JJ Kopchick, EO List, DE Berryman, ... Aging cell 14 (6), 1045-1054, 2015 | 81 | 2015 |
Canagliflozin extends life span in genetically heterogeneous male but not female mice RA Miller, DE Harrison, DB Allison, M Bogue, L Debarba, V Diaz, ... JCI insight 5 (21), 2020 | 78 | 2020 |
IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action M Sadagurski, RL Leshan, C Patterson, A Rozzo, A Kuznetsova, ... Cell metabolism 15 (5), 703-712, 2012 | 67 | 2012 |
Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis M Sadagurski, XC Dong, MG Myers Jr, MF White Molecular metabolism 3 (1), 55-63, 2014 | 54 | 2014 |
Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons G Cady, T Landeryou, M Garratt, JJ Kopchick, N Qi, D Garcia-Galiano, ... Molecular metabolism 6 (5), 393-405, 2017 | 51 | 2017 |
Integrating metabolism and longevity through insulin and IGF1 signaling M Sadagurski, MF White Endocrinology and Metabolism Clinics 42 (1), 127-148, 2013 | 41 | 2013 |
Long-lived crowded-litter mice exhibit lasting effects on insulin sensitivity and energy homeostasis M Sadagurski, T Landeryou, M Blandino-Rosano, G Cady, L Elghazi, ... American Journal of Physiology-Endocrinology and Metabolism 306 (11), E1305 …, 2014 | 38 | 2014 |
Insulin receptor substrate 2 plays diverse cell-specific roles in the regulation of glucose transport M Sadagurski, G Weingarten, CJ Rhodes, MF White, E Wertheimer Journal of Biological Chemistry 280 (15), 14536-14544, 2005 | 38 | 2005 |
Insulin receptor substrate 1 (IRS‐1) plays a unique role in normal epidermal physiology M Sadagurski, S Nofech‐Mozes, G Weingarten, MF White, T Kadowaki, ... Journal of cellular physiology 213 (2), 519-527, 2007 | 34 | 2007 |
Acarbose protects from central and peripheral metabolic imbalance induced by benzene exposure LK Debarba, A Mulka, JBM Lima, O Didyuk, P Fakhoury, L Koshko, ... Brain, Behavior, and Immunity 89, 87-99, 2020 | 27 | 2020 |
Neuroprotective effects of Canagliflozin: Lessons from aged genetically diverse UM‐HET3 mice HSM Jayarathne, LK Debarba, JJ Jaboro, BC Ginsburg, RA Miller, ... Aging Cell 21 (7), e13653, 2022 | 26 | 2022 |
Transient early food restriction leads to hypothalamic changes in the long‐lived crowded litter female mice M Sadagurski, T Landeryou, G Cady, A Bartke, E Bernal‐Mizrachi, ... Physiological reports 3 (4), e12379, 2015 | 25 | 2015 |
Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3β? RM Carew, M Sadagurski, R Goldschmeding, F Martin, MF White, ... BMC Developmental Biology 10, 1-8, 2010 | 24 | 2010 |
17-α-Estradiol has sex-specific effects on neuroinflammation that are partly reversed by gonadectomy LK Debarba, HSM Jayarathne, RA Miller, M Garratt, M Sadagurski The Journals of Gerontology: Series A 77 (1), 66-74, 2022 | 23 | 2022 |
ARCGHR Neurons Regulate Muscle Glucose Uptake JBM de Lima, LK Debarba, AC Rupp, N Qi, C Ubah, M Khan, O Didyuk, ... Cells 10 (5), 1093, 2021 | 22 | 2021 |
Canagliflozin retards age-related lesions in heart, kidney, liver, and adrenal gland in genetically heterogenous male mice JM Snyder, KM Casey, A Galecki, DE Harrison, H Jayarathne, N Kumar, ... Geroscience 45 (1), 385-397, 2023 | 21 | 2023 |