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Marianna Sadagurski
Marianna Sadagurski
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Human IL6 enhances leptin action in mice
M Sadagurski, L Norquay, J Farhang, K D’Aquino, K Copps, MF White
Diabetologia 53, 525-535, 2010
1842010
Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation
M Sadagurski, S Yakar, G Weingarten, M Holzenberger, CJ Rhodes, ...
Molecular and cellular biology 26 (7), 2675-2687, 2006
1552006
IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease
M Sadagurski, Z Cheng, A Rozzo, I Palazzolo, GR Kelley, X Dong, ...
The Journal of clinical investigation 121 (10), 4070-4081, 2011
1182011
Anti‐aging drugs reduce hypothalamic inflammation in a sex‐specific manner
M Sadagurski, G Cady, RA Miller
Aging Cell 16 (4), 652-660, 2017
812017
Growth hormone modulates hypothalamic inflammation in long‐lived pituitary dwarf mice
M Sadagurski, T Landeryou, G Cady, JJ Kopchick, EO List, DE Berryman, ...
Aging cell 14 (6), 1045-1054, 2015
812015
Canagliflozin extends life span in genetically heterogeneous male but not female mice
RA Miller, DE Harrison, DB Allison, M Bogue, L Debarba, V Diaz, ...
JCI insight 5 (21), 2020
782020
IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action
M Sadagurski, RL Leshan, C Patterson, A Rozzo, A Kuznetsova, ...
Cell metabolism 15 (5), 703-712, 2012
672012
Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis
M Sadagurski, XC Dong, MG Myers Jr, MF White
Molecular metabolism 3 (1), 55-63, 2014
542014
Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons
G Cady, T Landeryou, M Garratt, JJ Kopchick, N Qi, D Garcia-Galiano, ...
Molecular metabolism 6 (5), 393-405, 2017
512017
Integrating metabolism and longevity through insulin and IGF1 signaling
M Sadagurski, MF White
Endocrinology and Metabolism Clinics 42 (1), 127-148, 2013
412013
Long-lived crowded-litter mice exhibit lasting effects on insulin sensitivity and energy homeostasis
M Sadagurski, T Landeryou, M Blandino-Rosano, G Cady, L Elghazi, ...
American Journal of Physiology-Endocrinology and Metabolism 306 (11), E1305 …, 2014
382014
Insulin receptor substrate 2 plays diverse cell-specific roles in the regulation of glucose transport
M Sadagurski, G Weingarten, CJ Rhodes, MF White, E Wertheimer
Journal of Biological Chemistry 280 (15), 14536-14544, 2005
382005
Insulin receptor substrate 1 (IRS‐1) plays a unique role in normal epidermal physiology
M Sadagurski, S Nofech‐Mozes, G Weingarten, MF White, T Kadowaki, ...
Journal of cellular physiology 213 (2), 519-527, 2007
342007
Acarbose protects from central and peripheral metabolic imbalance induced by benzene exposure
LK Debarba, A Mulka, JBM Lima, O Didyuk, P Fakhoury, L Koshko, ...
Brain, Behavior, and Immunity 89, 87-99, 2020
272020
Neuroprotective effects of Canagliflozin: Lessons from aged genetically diverse UM‐HET3 mice
HSM Jayarathne, LK Debarba, JJ Jaboro, BC Ginsburg, RA Miller, ...
Aging Cell 21 (7), e13653, 2022
262022
Transient early food restriction leads to hypothalamic changes in the long‐lived crowded litter female mice
M Sadagurski, T Landeryou, G Cady, A Bartke, E Bernal‐Mizrachi, ...
Physiological reports 3 (4), e12379, 2015
252015
Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3β?
RM Carew, M Sadagurski, R Goldschmeding, F Martin, MF White, ...
BMC Developmental Biology 10, 1-8, 2010
242010
17-α-Estradiol has sex-specific effects on neuroinflammation that are partly reversed by gonadectomy
LK Debarba, HSM Jayarathne, RA Miller, M Garratt, M Sadagurski
The Journals of Gerontology: Series A 77 (1), 66-74, 2022
232022
ARCGHR Neurons Regulate Muscle Glucose Uptake
JBM de Lima, LK Debarba, AC Rupp, N Qi, C Ubah, M Khan, O Didyuk, ...
Cells 10 (5), 1093, 2021
222021
Canagliflozin retards age-related lesions in heart, kidney, liver, and adrenal gland in genetically heterogenous male mice
JM Snyder, KM Casey, A Galecki, DE Harrison, H Jayarathne, N Kumar, ...
Geroscience 45 (1), 385-397, 2023
212023
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