| Neuronal activity enhances tau propagation and tau pathology in vivo JW Wu, SA Hussaini, IM Bastille, GA Rodriguez, A Mrejeru, K Rilett, ... Nature neuroscience 19 (8), 1085-1092, 2016 | 803 | 2016 |
| Selective vulnerability in neurodegenerative diseases H Fu, J Hardy, KE Duff Nature neuroscience 21 (10), 1350-1358, 2018 | 566 | 2018 |
| scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses J Wang, A Ma, Y Chang, J Gong, Y Jiang, R Qi, C Wang, H Fu, Q Ma, ... Nature communications 12 (1), 1882, 2021 | 508 | 2021 |
| Tau pathology induces excitatory neuron loss, grid cell dysfunction, and spatial memory deficits reminiscent of early Alzheimer’s disease H Fu, GA Rodriguez, M Herman, S Emrani, E Nahmani, G Barrett, ... Neuron 93 (3), 533-541. e5, 2017 | 287 | 2017 |
| A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology H Fu, A Possenti, R Freer, Y Nakano, NC Hernandez Villegas, M Tang, ... Nature neuroscience 22 (1), 47-56, 2019 | 218 | 2019 |
| Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers S Li, M Jin, D Zhang, T Yang, T Koeglsperger, H Fu, DJ Selkoe Neuron 77 (5), 929-941, 2013 | 207 | 2013 |
| Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia H Fu, B Liu, JL Frost, S Hong, M Jin, B Ostaszewski, GM Shankar, ... Glia, 2012 | 194 | 2012 |
| A shared disease-associated oligodendrocyte signature among multiple CNS pathologies M Kenigsbuch, P Bost, S Halevi, Y Chang, S Chen, Q Ma, R Hajbi, ... Nature neuroscience 25 (7), 876-886, 2022 | 163 | 2022 |
| Amyloid-β Immunotherapy for Alzheimer's Disease HJ Fu, B Liu, JL Frost, CA Lemere CNS & neurological disorders drug targets 9 (2), 197, 2010 | 152 | 2010 |
| Novel dimeric acetylcholinesterase inhibitor bis (7)-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors W Li, R Pi, HHN Chan, H Fu, NTK Lee, HW Tsang, Y Pu, DC Chang, C Li, ... Journal of Biological Chemistry 280 (18), 18179-18188, 2005 | 142 | 2005 |
| Bis (7)‐tacrine attenuates β amyloid‐induced neuronal apoptosis by regulating L‐type calcium channels H Fu, W Li, Y Lao, J Luo, NTK Lee, KKW Kan, HW Tsang, KWK Tsim, ... Journal of neurochemistry 98 (5), 1400-1410, 2006 | 123 | 2006 |
| scREAD: a single-cell RNA-Seq database for Alzheimer's disease J Jiang, C Wang, R Qi, H Fu, Q Ma Iscience 23 (11), 2020 | 102 | 2020 |
| Promising anti-Alzheimer’s dimer bis (7)-tacrine reduces β-amyloid generation by directly inhibiting BACE-1 activity H Fu, W Li, J Luo, NTK Lee, M Li, KWK Tsim, Y Pang, MBH Youdim, ... Biochemical and biophysical research communications 366 (3), 631-636, 2008 | 88 | 2008 |
| Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease S Chen, Y Chang, L Li, D Acosta, Y Li, Q Guo, C Wang, E Turkes, ... Acta neuropathologica communications 10 (1), 188, 2022 | 79* | 2022 |
| Aluminum-induced apoptosis in cultured cortical neurons and its effect on SAPK/JNK signal transduction pathway HJ Fu, QS Hu, ZN Lin, TL Ren, H Song, CK Cai, SZ Dong Brain research 980 (1), 11-23, 2003 | 75 | 2003 |
| MER5101, a novel Aβ1-15: DT conjugate vaccine, generates a robust anti-Aβ antibody response and attenuates Aβ pathology and cognitive deficits in APPswe/PS1ΔE9 transgenic mice B Liu, JL Frost, J Sun, H Fu, S Grimes, P Blackburn, CA Lemere Journal of Neuroscience 33 (16), 7027-7037, 2013 | 70 | 2013 |
| F‐box/LRR‐repeat protein 7 is genetically associated with Alzheimer's disease G Tosto, H Fu, BN Vardarajan, JH Lee, R Cheng, D Reyes‐Dumeyer, ... Annals of clinical and translational neurology 2 (8), 810-820, 2015 | 66 | 2015 |
| Synergistic neuroprotection by bis (7)-tacrine via concurrent blockade of N-methyl-D-aspartate receptors and neuronal nitric-oxide synthase W Li, J Xue, C Niu, H Fu, CSC Lam, J Luo, HHN Chan, H Xue, KKW Kan, ... Molecular pharmacology 71 (5), 1258-1267, 2007 | 65 | 2007 |
| Promising multifunctional anti-Alzheimer's dimer bis (7)-Cognitin acting as an activator of protein kinase C regulates activities of α-secretase and BACE-1 concurrently H Fu, J Dou, W Li, W Cui, S Mak, Q Hu, J Luo, CSC Lam, Y Pang, ... European journal of pharmacology 623 (1-3), 14-21, 2009 | 51 | 2009 |
| Modeling neurodegenerative diseases with cerebral organoids and other three-dimensional culture systems: Focus on Alzheimer’s disease L Venkataraman, SR Fair, CA McElroy, ME Hester, H Fu Stem cell reviews and reports, 1-22, 2020 | 50 | 2020 |