| Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures J Debnath, SK Muthuswamy, JS Brugge Methods 30 (3), 256-268, 2003 | 2378 | 2003 |
| The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini J Debnath, KR Mills, NL Collins, MJ Reginato, SK Muthuswamy, ... Cell 111 (1), 29-40, 2002 | 961 | 2002 |
| Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell–and patient-derived tumor organoids L Huang, A Holtzinger, I Jagan, M BeGora, I Lohse, N Ngai, C Nostro, ... Nature medicine 21 (11), 1364-1371, 2015 | 782 | 2015 |
| Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erb B2)-overexpressing breast cancer cells in vitro and in vivo SL Moulder, FM Yakes, SK Muthuswamy, R Bianco, JF Simpson, ... Cancer research 61 (24), 8887-8895, 2001 | 718 | 2001 |
| ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini SK Muthuswamy, D Li, S Lelievre, MJ Bissell, JS Brugge Nature cell biology 3 (9), 785-792, 2001 | 714 | 2001 |
| Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis MJ Reginato, KR Mills, JK Paulus, DK Lynch, DC Sgroi, J Debnath, ... Nature cell biology 5 (8), 733-740, 2003 | 675 | 2003 |
| HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors SE Wang, A Narasanna, M Perez-Torres, B Xiang, FY Wu, S Yang, ... Cancer cell 10 (1), 25-38, 2006 | 591 | 2006 |
| Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma L Zhan, A Rosenberg, KC Bergami, M Yu, Z Xuan, AB Jaffe, C Allred, ... Cell 135 (5), 865-878, 2008 | 522 | 2008 |
| Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo-and heterodimers SK Muthuswamy, M Gilman, JS Brugge Molecular and cellular biology 19 (10), 6845-6857, 1999 | 495 | 1999 |
| The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation O Anczuków, AZ Rosenberg, M Akerman, S Das, L Zhan, R Karni, ... Nature structural & molecular biology 19 (2), 220-228, 2012 | 492 | 2012 |
| Targeting the disordered C terminus of PTP1B with an allosteric inhibitor N Krishnan, D Koveal, DH Miller, B Xue, SD Akshinthala, J Kragelj, ... Nature chemical biology 10 (7), 558-566, 2014 | 394 | 2014 |
| Par6–aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control V Aranda, T Haire, ME Nolan, JP Calarco, AZ Rosenberg, JP Fawcett, ... Nature cell biology 8 (11), 1235-1245, 2006 | 329 | 2006 |
| Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4 X Dai, W Gan, X Li, S Wang, W Zhang, L Huang, S Liu, Q Zhong, J Guo, ... Nature medicine 23 (9), 1063-1071, 2017 | 309 | 2017 |
| Cooperation of the ErbB2 receptor and transforming growth factor β in induction of migration and invasion in mammary epithelial cells SE Seton-Rogers, Y Lu, LM Hines, M Koundinya, J LaBaer, ... Proceedings of the National Academy of Sciences 101 (5), 1257-1262, 2004 | 306 | 2004 |
| Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity SK Muthuswamy, PM Siegel, DL Dankort, MA Webster, WJ Muller Molecular and cellular biology 14 (1), 735-743, 1994 | 302 | 1994 |
| Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice. CT Guy, SK Muthuswamy, RD Cardiff, P Soriano, WJ Muller Genes & development 8 (1), 23-32, 1994 | 277 | 1994 |
| A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells I Ibarra, Y Erlich, SK Muthuswamy, R Sachidanandam, GJ Hannon Genes & development 21 (24), 3238-3243, 2007 | 267 | 2007 |
| Requirement for both Shc and phosphatidylinositol 3′ kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis MA Webster, JN Hutchinson, MJ Rauh, SK Muthuswamy, M Anton, ... Molecular and cellular biology 18 (4), 2344-2359, 1998 | 245 | 1998 |
| Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells HM Bill, B Knudsen, SL Moores, SK Muthuswamy, VR Rao, JS Brugge, ... Molecular and cellular biology 24 (19), 8586-8599, 2004 | 225 | 2004 |
| ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis WM Keyes, M Pecoraro, V Aranda, E Vernersson-Lindahl, W Li, H Vogel, ... Cell stem cell 8 (2), 164-176, 2011 | 224 | 2011 |
