The expanding landscape of ‘oncohistone’mutations in human cancers BA Nacev, L Feng, JD Bagert, AE Lemiesz, JJ Gao, AA Soshnev, ... Nature 567 (7749), 473-478, 2019 | 360 | 2019 |
Impaired cell fate through gain-of-function mutations in a chromatin reader L Wan, S Chong, F Xuan, A Liang, X Cui, L Gates, TS Carroll, Y Li, L Feng, ... Nature 577 (7788), 121-126, 2020 | 127 | 2020 |
Oncohistone mutations enhance chromatin remodeling and alter cell fates JD Bagert, MM Mitchener, AL Patriotis, BE Dul, F Wojcik, BA Nacev, ... Nature chemical biology 17 (4), 403-411, 2021 | 74 | 2021 |
Asymmetric distribution of histones during Drosophila male germline stem cell asymmetric divisions V Tran, L Feng, X Chen Chromosome research 21, 255-269, 2013 | 38 | 2013 |
Loss of UTX/KDM6A and the activation of FGFR3 converge to regulate differentiation gene-expression programs in bladder cancer D Barrows, L Feng, TS Carroll, CD Allis Proceedings of the National Academy of Sciences 117 (41), 25732-25741, 2020 | 37 | 2020 |
Enhancer of polycomb coordinates multiple signaling pathways to promote both cyst and germline stem cell differentiation in the Drosophila adult testis L Feng, Z Shi, X Chen PLoS genetics 13 (2), e1006571, 2017 | 33 | 2017 |
Epigenetic regulation of germ cells—remember or forget? L Feng, X Chen Current opinion in genetics & development 31, 20-27, 2015 | 33 | 2015 |
Dynactin integrity depends upon direct binding of dynamitin to Arp1 FKY Cheong, L Feng, A Sarkeshik, JR Yates III, TA Schroer Molecular biology of the cell 25 (14), 2171-2180, 2014 | 26 | 2014 |
An aminopeptidase in the Drosophila testicular niche acts in germline stem cell maintenance and spermatogonial dedifferentiation C Lim, S Gandhi, ML Biniossek, L Feng, O Schilling, S Urban, X Chen Cell reports 13 (2), 315-325, 2015 | 22 | 2015 |
Enhancer of polycomb maintains germline activity and genome integrity in Drosophila testis L Feng, Z Shi, J Xie, B Ma, X Chen Cell Death & Differentiation 25 (8), 1486-1502, 2018 | 16 | 2018 |
Polycomb group gene E (z) is required for spermatogonial dedifferentiation in Drosophila adult testis SH Eun, L Feng, L Cedeno-Rosario, Q Gan, G Wei, K Cui, K Zhao, ... Journal of molecular biology 429 (13), 2030-2041, 2017 | 15 | 2017 |
Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation L Feng, D Barrows, L Zhong, K Mätlik, EG Porter, AM Djomo, I Yau, ... bioRxiv, 2023 | 1 | 2023 |
Biochemical and Cellular Libraries Reveal Cancer-Associated Histone Mutations That Perturb Nucleosome Structure and Inhibit Cell Differentiation J Bagert, MM Mitchener, AE Lemiesz, BE Dul, F Wojcik, BA Nacev, L Feng, ... 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |