| The cellular and signaling networks linking the immune system and metabolism in disease O Osborn, JM Olefsky Nature medicine 18 (3), 363-374, 2012 | 1815 | 2012 |
| Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance S Fang, JM Suh, SM Reilly, E Yu, O Osborn, D Lackey, E Yoshihara, ... Nature medicine 21 (2), 159-165, 2015 | 795 | 2015 |
| LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes P Li, DY Oh, G Bandyopadhyay, WS Lagakos, S Talukdar, O Osborn, ... Nature medicine 21 (3), 239-247, 2015 | 346 | 2015 |
| Hematopoietic-derived galectin-3 causes cellular and systemic insulin resistance P Li, S Liu, M Lu, G Bandyopadhyay, D Oh, T Imamura, AMF Johnson, ... Cell 167 (4), 973-984. e12, 2016 | 304 | 2016 |
| Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases S Talukdar, JM Olefsky, O Osborn Trends in pharmacological sciences 32 (9), 543-550, 2011 | 303 | 2011 |
| Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer JM Suh, JW Jonker, M Ahmadian, R Goetz, D Lackey, O Osborn, Z Huang, ... Nature 513 (7518), 436-439, 2014 | 276 | 2014 |
| Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction S Schenk, CE McCurdy, A Philp, MZ Chen, MJ Holliday, ... The Journal of clinical investigation 121 (11), 4281-4288, 2011 | 220 | 2011 |
| Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice H Morinaga, R Mayoral, J Heinrichsdorff, O Osborn, N Franck, N Hah, ... Diabetes 64 (4), 1120-1130, 2015 | 201 | 2015 |
| Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced obesity O Osborn, SE Brownell, M Sanchez-Alavez, D Salomon, H Gram, T Bartfai Cytokine 44 (1), 141-148, 2008 | 200 | 2008 |
| Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity R Mayoral, O Osborn, J McNelis, AM Johnson, CL Izquierdo, H Chung, ... Molecular metabolism 4 (5), 378-391, 2015 | 169 | 2015 |
| Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling W Ying, J Wollam, JM Ofrecio, G Bandyopadhyay, D El Ouarrat, YS Lee, ... The Journal of clinical investigation 127 (3), 1019-1030, 2017 | 133 | 2017 |
| Insulin causes hyperthermia by direct inhibition of warm-sensitive neurons M Sanchez-Alavez, IV Tabarean, O Osborn, K Mitsukawa, J Schaefer, ... Diabetes 59 (1), 43-50, 2010 | 103 | 2010 |
| Degradation of splicing factor SRSF3 contributes to progressive liver disease D Kumar, M Das, C Sauceda, LG Ellies, K Kuo, P Parwal, M Kaur, L Jih, ... The Journal of clinical investigation 129 (10), 4477-4491, 2019 | 101 | 2019 |
| A locus for autosomal dominant “pure” hereditary spastic paraplegia maps to chromosome 19q13 E Reid, AM Dearlove, O Osborn, MT Rogers, DC Rubinsztein The American Journal of Human Genetics 66 (2), 728-732, 2000 | 99 | 2000 |
| Insights into the roles of the inflammatory mediators IL-1, IL-18 and PGE2 in obesity and insulin resistance O Osborn, H Gram, EP Zorrilla, B Conti, T Bartfai Swiss medical weekly 138 (4546), 665-673, 2008 | 84 | 2008 |
| Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues M Lu, DA Sarruf, P Li, O Osborn, M Sanchez-Alavez, S Talukdar, A Chen, ... Journal of Biological Chemistry 288 (15), 10722-10735, 2013 | 66 | 2013 |
| G protein–coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice O Osborn, J McNelis, M Sanchez-Alavez, S Talukdar, M Lu, PP Li, ... The Journal of clinical investigation 122 (7), 2444-2453, 2012 | 66 | 2012 |
| Positive reinforcing mechanisms between GPR120 and PPARγ modulate insulin sensitivity VA Paschoal, E Walenta, S Talukdar, AR Pessentheiner, O Osborn, ... Cell metabolism 31 (6), 1173-1188. e5, 2020 | 62 | 2020 |
| RalA controls glucose homeostasis by regulating glucose uptake in brown fat Y Skorobogatko, M Dragan, C Cordon, SM Reilly, CW Hung, W Xia, ... Proceedings of the National Academy of Sciences 115 (30), 7819-7824, 2018 | 51 | 2018 |
| Diet-induced obesity and weight loss alter bile acid concentrations and bile acid–sensitive gene expression in insulin target tissues of C57BL/6J mice MR La Frano, A Hernandez-Carretero, N Weber, K Borkowski, ... Nutrition Research 46, 11-21, 2017 | 49 | 2017 |