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Andrew P Patton
Andrew P Patton
MRC Laboratory of Molecular Biology
Dirección de correo verificada de mrc-lmb.cam.ac.uk
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Astrocytes control circadian timekeeping in the suprachiasmatic nucleus via glutamatergic signaling
M Brancaccio, AP Patton, JE Chesham, ES Maywood, MH Hastings
Neuron 93 (6), 1420-1435. e5, 2017
4442017
Cell-autonomous clock of astrocytes drives circadian behavior in mammals
M Brancaccio, MD Edwards, AP Patton, NJ Smyllie, JE Chesham, ...
Science 363 (6423), 187-192, 2019
3322019
The suprachiasmatic nucleus
AP Patton, MH Hastings
Current Biology 28 (15), R816-R822, 2018
1412018
PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity
Y Nakamura, CL Wood, AP Patton, N Jaafari, JM Henley, JR Mellor, ...
The EMBO journal 30 (4), 719-730, 2011
1152011
Single‐cell transcriptomics of suprachiasmatic nuclei reveal a Prokineticin‐driven circadian network
EL Morris, AP Patton, JE Chesham, A Crisp, A Adamson, MH Hastings
The EMBO Journal 40 (20), e108614, 2021
652021
The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit
AP Patton, MD Edwards, NJ Smyllie, R Hamnett, JE Chesham, ...
Nature Communications 11 (1), 3394, 2020
642020
Combined pharmacological and genetic manipulations unlock unprecedented temporal elasticity and reveal phase-specific modulation of the molecular circadian clock of the mouse …
AP Patton, JE Chesham, MH Hastings
Journal of Neuroscience 36 (36), 9326-9341, 2016
432016
Translational switching of Cry1 protein expression confers reversible control of circadian behavior in arrhythmic Cry-deficient mice
ES Maywood, TS Elliott, AP Patton, TP Krogager, JE Chesham, RJ Ernst, ...
Proceedings of the National Academy of Sciences 115 (52), E12388-E12397, 2018
422018
Molecular-genetic manipulation of the suprachiasmatic nucleus circadian clock
MH Hastings, NJ Smyllie, AP Patton
Journal of molecular biology 432 (12), 3639-3660, 2020
382020
Astrocytes sustain circadian oscillation and bidirectionally determine circadian period, but do not regulate circadian phase in the suprachiasmatic nucleus
AP Patton, NJ Smyllie, JE Chesham, MH Hastings
Journal of Neuroscience 42 (28), 5522-5537, 2022
302022
Astrocytic control of extracellular GABA drives circadian timekeeping in the suprachiasmatic nucleus
AP Patton, EL Morris, D McManus, H Wang, Y Li, JW Chin, MH Hastings
Proceedings of the National Academy of Sciences 120 (21), e2301330120, 2023
282023
The mammalian circadian time-keeping system
AP Patton, MH Hastings
Journal of Huntington's disease 12 (2), 91-104, 2023
282023
Cryptochrome 1 as a state variable of the circadian clockwork of the suprachiasmatic nucleus: Evidence from translational switching
D McManus, L Polidarova, NJ Smyllie, AP Patton, JE Chesham, ...
Proceedings of the National Academy of Sciences 119 (34), e2203563119, 2022
102022
Cells and Circuits of the Suprachiasmatic Nucleus and the Control of Circadian Behaviour and Sleep
AP Patton, MH Hastings, NJ Smyllie
Sleep and Clocks in Aging and Longevity, 33-70, 2023
52023
Neuron-Astrocyte Interactions and Circadian Timekeeping in Mammals
NJ Smyllie, MH Hastings, AP Patton
The Neuroscientist, 10738584241245307, 2024
12024
Astrocytic-neuronal interplay controls circadian pacemaking in mammals
M Brancaccio, AP Patton, JE Chesham, ES Maywood, MH Hastings
GLIA 65, E277-E277, 2017
12017
PERfect Day: reversible and dose‐dependent control of circadian time‐keeping in the mouse suprachiasmatic nucleus by translational switching of PERIOD2 protein expression
D McManus, AP Patton, NJ Smyllie, JW Chin, MH Hastings
European Journal of Neuroscience 60 (7), 5537-5552, 2024
2024
Supplemental Information
M Brancaccio, AP Patton, JE Chesham, ES Maywood, MH Hastings
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Artículos 1–18