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Mark Duerkop
Mark Duerkop
CEO Novasign GmbH
Dirección de correo verificada de novasign.at - Página principal
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Impact of cavitation, high shear stress and air/liquid interfaces on protein aggregation
M Duerkop, E Berger, A Dürauer, A Jungbauer
Biotechnology journal 13 (7), 1800062, 2018
1182018
Hybrid modeling and intensified DoE: an approach to accelerate upstream process characterization
B Bayer, G Striedner, M Duerkop
Biotechnology journal 15 (9), 2000121, 2020
512020
Hybrid modeling of cross-flow filtration: Predicting the flux evolution and duration of ultrafiltration processes
M Krippl, A Dürauer, M Duerkop
Separation and Purification Technology 248, 117064, 2020
492020
A comprehensive antigen production and characterisation study for easy-to-implement, specific and quantitative SARS-CoV-2 serotests
M Klausberger, M Duerkop, H Haslacher, G Wozniak-Knopp, ...
EBioMedicine 67, 2021
462021
Comparison of modeling methods for DoE‐based holistic upstream process characterization
B Bayer, M von Stosch, G Striedner, M Duerkop
Biotechnology Journal 15 (5), 1900551, 2020
452020
Influence of cavitation and high shear stress on HSA aggregation behavior
M Duerkop, E Berger, A Dürauer, A Jungbauer
Engineering in life sciences 18 (3), 169-178, 2018
432018
Digital twin application for model-based doe to rapidly identify ideal process conditions for space-time yield optimization
B Bayer, R Dalmau Diaz, M Melcher, G Striedner, M Duerkop
Processes 9 (7), 1109, 2021
412021
Model transferability and reduced experimental burden in cell culture process development facilitated by hybrid modeling and intensified design of experiments
B Bayer, M Duerkop, G Striedner, B Sissolak
Frontiers in Bioengineering and Biotechnology 9, 740215, 2021
272021
Hybrid modeling reduces experimental effort to predict performance of serial and parallel single-pass tangential flow filtration
M Krippl, T Kargl, M Duerkop, A Dürauer
Separation and Purification Technology 276, 119277, 2021
262021
The shortcomings of accurate rate estimations in cultivation processes and a solution for precise and robust process modeling
B Bayer, B Sissolak, M Duerkop, M Von Stosch, G Striedner
Bioprocess and biosystems engineering 43, 169-178, 2020
262020
Soft sensor based on 2D‐fluorescence and process data enabling real‐time estimation of biomass in Escherichia coli cultivations
B Bayer, M von Stosch, M Melcher, M Duerkop, G Striedner
Engineering in Life Sciences 20 (1-2), 26-35, 2020
202020
Comparison of mechanistic and hybrid modeling approaches for characterization of a CHO cultivation process: Requirements, pitfalls and solution paths
B Bayer, M Duerkop, R Pörtner, J Möller
Biotechnology journal 18 (1), 2200381, 2023
192023
Spike protein antibodies mediate the apparent correlation between SARS-CoV-2 nucleocapsid antibodies and neutralization test results
T Perkmann, T Koller, N Perkmann-Nagele, M Klausberger, M Duerkop, ...
Microbiology spectrum 9 (1), 10.1128/spectrum. 00218-21, 2021
132021
Hybrid modeling for simultaneous prediction of flux, rejection factor and concentration in two-component crossflow ultrafiltration
M Krippl, I Bofarull-Manzano, M Duerkop, A Dürauer
Processes 8 (12), 1625, 2020
122020
Production of full-length SARS-CoV-2 nucleocapsid protein from Escherichia coli optimized by native hydrophobic interaction chromatography hyphenated to multi-angle light …
J De Vos, PP Aguilar, C Köppl, A Fischer, C Grünwald-Gruber, M Dürkop, ...
Talanta 235, 122691, 2021
102021
High shear resistance of insect cells: the basis for substantial improvements in cell culture process design
F Strobl, M Duerkop, D Palmberger, G Striedner
Scientific Reports 11 (1), 9413, 2021
102021
Increasing both specificity and sensitivity of SARS-CoV-2 antibody tests by using an adaptive orthogonal testing approach
T Perkmann, T Koller, N Perkmann-Nagele, M Ozsvar-Kozma, D Eyre, ...
9*2020
Boost dynamic protocols for producing mammalian biopharmaceuticals with intensified DoE—A practical guide to analyses with OLS and hybrid modeling
V Nold, L Junghans, B Bayer, L Bisgen, M Duerkop, R Drerup, B Presser, ...
Frontiers in Chemical Engineering 4, 1044245, 2023
72023
Fundamental insights in early‐stage inclusion body formation
J Kopp, B Bayer, C Slouka, G Striedner, M Dürkop, O Spadiut
Microbial Biotechnology 16 (5), 893-900, 2023
62023
A comprehensive antigen production and characterisation study for easy-to-implement, specific and quantitative SARS-CoV-2 serotests, EBioMedicine 67 (2021)
M Klausberger, M Duerkop, H Haslacher, G Wozniak-Knopp, ...
62021
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Artículos 1–20