| The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs A Akinc, MA Maier, M Manoharan, K Fitzgerald, M Jayaraman, S Barros, ... Nature nanotechnology 14 (12), 1084-1087, 2019 | 1292 | 2019 |
| mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability L Schoenmaker, D Witzigmann, JA Kulkarni, R Verbeke, G Kersten, ... International journal of pharmaceutics 601, 120586, 2021 | 1171 | 2021 |
| The current landscape of nucleic acid therapeutics JA Kulkarni, D Witzigmann, SB Thomson, S Chen, BR Leavitt, PR Cullis, ... Nature nanotechnology 16 (6), 630-643, 2021 | 998 | 2021 |
| The role of lipid components in lipid nanoparticles for vaccines and gene therapy CH Albertsen, JA Kulkarni, D Witzigmann, M Lind, K Petersson, ... Advanced drug delivery reviews 188, 114416, 2022 | 578 | 2022 |
| On the formation and morphology of lipid nanoparticles containing ionizable cationic lipids and siRNA JA Kulkarni, MM Darjuan, JE Mercer, S Chen, R Van Der Meel, ... ACS nano 12 (5), 4787-4795, 2018 | 502 | 2018 |
| Lipid nanoparticles enabling gene therapies: from concepts to clinical utility JA Kulkarni, PR Cullis, R Van Der Meel Nucleic acid therapeutics 28 (3), 146-157, 2018 | 496 | 2018 |
| Lipid nanoparticle technology for clinical translation of siRNA therapeutics JA Kulkarni, D Witzigmann, S Chen, PR Cullis, R van der Meel Accounts of chemical research 52 (9), 2435-2444, 2019 | 432 | 2019 |
| On the role of helper lipids in lipid nanoparticle formulations of siRNA JA Kulkarni, D Witzigmann, J Leung, YYC Tam, PR Cullis Nanoscale 11 (45), 21733-21739, 2019 | 316 | 2019 |
| Lipid nanoparticle technology for therapeutic gene regulation in the liver D Witzigmann, JA Kulkarni, J Leung, S Chen, PR Cullis, R van der Meel Advanced drug delivery reviews 159, 344-363, 2020 | 311 | 2020 |
| State‐of‐the‐art design and rapid‐mixing production techniques of lipid nanoparticles for nucleic acid delivery MJW Evers, JA Kulkarni, R van der Meel, PR Cullis, P Vader, ... Small methods 2 (9), 1700375, 2018 | 293 | 2018 |
| Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA JA Kulkarni, JL Myhre, S Chen, YYC Tam, A Danescu, JM Richman, ... Nanomedicine: Nanotechnology, Biology and Medicine 13 (4), 1377-1387, 2017 | 210 | 2017 |
| Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads JA Kulkarni, D Witzigmann, J Leung, R van der Meel, J Zaifman, ... Nanoscale 11 (18), 9023-9031, 2019 | 127 | 2019 |
| Induction of bleb structures in lipid nanoparticle formulations of mRNA leads to improved transfection potency MHY Cheng, J Leung, Y Zhang, C Strong, G Basha, A Momeni, Y Chen, ... Advanced Materials 35 (31), 2303370, 2023 | 96 | 2023 |
| Characterization of Lipid Nanoparticles Containing Ionizable Cationic Lipids Using Design-of-Experiments Approach T Terada, JA Kulkarni, A Huynh, S Chen, R van der Meel, YYC Tam, ... Langmuir, 2021 | 85 | 2021 |
| Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved delivery WL Tang, WH Tang, A Szeitz, J Kulkarni, P Cullis, SD Li Biomaterials 166, 13-26, 2018 | 78 | 2018 |
| Robust microfluidic technology and new lipid composition for fabrication of curcumin-loaded liposomes: effect on the anticancer activity and safety of cisplatin N Hamano, R Böttger, SE Lee, Y Yang, JA Kulkarni, S Ip, PR Cullis, ... Molecular Pharmaceutics 16 (9), 3957-3967, 2019 | 67 | 2019 |
| Rapid synthesis of lipid nanoparticles containing hydrophobic inorganic nanoparticles JA Kulkarni, YYC Tam, S Chen, YK Tam, J Zaifman, PR Cullis, S Biswas Nanoscale 9 (36), 13600-13609, 2017 | 66 | 2017 |
| Ionizable amino lipid interactions with POPC: implications for lipid nanoparticle function M Ramezanpour, ML Schmidt, I Bodnariuc, JA Kulkarni, SSW Leung, ... Nanoscale 11 (30), 14141-14146, 2019 | 61 | 2019 |
| Coating of PLA-nanoparticles with cyclic, arginine-rich cell penetrating peptides enables oral delivery of liraglutide P Uhl, C Grundmann, M Sauter, P Storck, A Tursch, S Özbek, K Leotta, ... Nanomedicine: Nanotechnology, Biology and Medicine 24, 102132, 2020 | 59 | 2020 |
| Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids S Chen, J Zaifman, JA Kulkarni, IV Zhigaltsev, YK Tam, MA Ciufolini, ... Journal of controlled release 286, 46-54, 2018 | 56 | 2018 |
Pieter R CullisProfessor Biochemistry, University of BCDirección de correo verificada de mail.ubc.ca
