| Identification of Less Lipophilic Riminophenazine Derivatives for the Treatment of Drug-Resistant Tuberculosis D Zhang, Y Lu, K Liu, B Liu, J Wang, G Zhang, H Zhang, Y Liu, B Wang, ... Journal of Medicinal Chemistry 55 (19), 8409-8417, 2012 | 91 | 2012 |
| Design, synthesis, and kinetic analysis of potent protein N-terminal methyltransferase 1 inhibitors G Zhang, SL Richardson, Y Mao, R Huang Organic & Biomolecular Chemistry 13 (14), 4149-4154, 2015 | 65 | 2015 |
| Kinetic Mechanism of Protein N-terminal Methyltransferase 1 SL Richardson, Y Mao, G Zhang, P Hanjra, DL Peterson, R Huang Journal of Biological Chemistry 290 (18), 11601-11610, 2015 | 48 | 2015 |
| Emerging roles of Aurora-A kinase in cancer therapy resistance D Zheng, J Li, H Yan, G Zhang, W Li, E Chu, N Wei Acta Pharmaceutica Sinica B 13 (7), 2826-2843, 2023 | 45 | 2023 |
| AAA ATPases as therapeutic targets: Structure, functions, and small-molecule inhibitors G Zhang, S Li, KW Cheng, TF Chou European Journal of Medicinal Chemistry 219, 113446, 2021 | 45 | 2021 |
| Systematic Evaluation of Structure-Activity Relationships of the Riminophenazine Class and Discovery of a C2 Pyridylamino Series for the Treatment of Multidrug-Resistant … B Liu, K Liu, Y Lu, D Zhang, T Yang, X Li, C Ma, M Zheng, B Wang, ... Molecules 17 (4), 4545-4559, 2012 | 39 | 2012 |
| Spirocyclic and Bicyclic 8-Nitrobenzothiazinone for Tuberculosis with Improved Physicochemical and Pharmacokinetic Properties G Zhang, M Howe, CC Aldrich ACS Medicinal Chemistry Letters 10 (3), 348-351, 2019 | 36 | 2019 |
| A Cinchona Alkaloid Antibiotic that Appears to Target ATP Synthase in Streptococcus pneumoniae X Wang, Y Zeng, L Sheng, P Larson, X Liu, X Zou, S Wang, K Guo, C Ma, ... Journal of medicinal chemistry 62 (5), 2305-2332, 2019 | 35 | 2019 |
| AI is a viable alternative to high throughput screening: a 318-target study Scientific reports 14 (1), 7526, 2024 | 34 | 2024 |
| Quercetin amorphous solid dispersions prepared by hot melt extrusion with enhanced solubility and intestinal absorption X Shi, N Fan, G Zhang, J Sun, Z He, J Li Pharmaceutical development and technology 25 (4), 472-481, 2020 | 34 | 2020 |
| Identification of Diaryl-Quinoline Compounds as Entry Inhibitors of Ebola Virus Q Cui, H Cheng, R Xiong, G Zhang, R Du, M Anantpadma, RA Davey, ... Viruses 10 (12), 678, 2018 | 34 | 2018 |
| Virtual screening of small molecular inhibitors against DprE1 G Zhang, S Guo, H Cui, J Qi Molecules 23 (3), 524, 2018 | 33 | 2018 |
| The different metabolism of morusin in various species and its potent inhibition against UDP-glucuronosyltransferase (UGT) and cytochrome p450 (CYP450) enzymes X Shi, S Yang, G Zhang, Y Song, D Su, Y Liu, F Guo, L Shan, J Cai Xenobiotica 46 (5), 467-476, 2016 | 29 | 2016 |
| Comparison of the in vitro metabolism of psoralidin among different species and characterization of its inhibitory effect against UDP-glucuronosyltransferase (UGT) or … X Shi, G Zhang, B Mackie, S Yang, J Wang, L Shan Journal of Chromatography B 1029, 145-156, 2016 | 28 | 2016 |
| DNA damage and apoptosis induced by a potent orally podophyllotoxin derivative in breast cancer Y Wang, H Sun, Z Xiao, G Zhang, D Zhang, X Bao, F Li, S Wu, Y Gao, ... Cell Communication and Signaling 16, 1-13, 2018 | 27 | 2018 |
| Comparison of the Inhibitory Potential of Bavachalcone and Corylin against UDP-Glucuronosyltransferases L Shan, S Yang, G Zhang, D Zhou, Z Qiu, L Tian, H Yuan, Y Feng, X Shi Evidence-Based Complementary and Alternative Medicine 2014, Article ID 958937, 2014 | 25 | 2014 |
| Design and synthesis of indoleamine 2, 3-dioxygenase 1 inhibitors and evaluation of their use as anti-tumor agents H Wen, Y Liu, S Wang, T Wang, G Zhang, X Chen, Y Li, H Cui, F Lai, ... Molecules 24 (11), 2124, 2019 | 24 | 2019 |
| A direct, ratiometric, and quantitative MALDI–MS assay for protein methyltransferases and acetyltransferases SL Richardson, P Hanjra, G Zhang, BD Mackie, DL Peterson, R Huang Analytical biochemistry 478, 59-64, 2015 | 22 | 2015 |
| Facile Synthesis of SAM-Peptide Conjugates through Alkyl Linkers Targeting Protein N-terminal Methyltransferase 1 G Zhang, R Huang RSC Advances 6 (8), 6768-6771, 2016 | 20 | 2016 |
| A Covalent p97/VCP ATPase Inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells G Zhang, S Li, F Wang, AC Jones, AFG Goldberg, B Lin, S Virgil, ... European Journal of Medicinal Chemistry 213, 113148, 2021 | 19 | 2021 |
Prof. Huaqing CuiInstitute of Materia Medica, Chinese Academy of Medical Sciencesایمیل تأیید شده در imm.ac.cn