Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein C Toelzer, K Gupta, SKN Yadav, U Borucu, AD Davidson, ... Science 370 (6517), 725-730, 2020 | 404 | 2020 |
Molecular simulations suggest vitamins, retinoids and steroids as ligands of the free fatty acid pocket of the SARS‐CoV‐2 Spike protein DK Shoemark, CK Colenso, C Toelzer, K Gupta, RB Sessions, ... Angewandte Chemie 133 (13), 7174-7186, 2021 | 97 | 2021 |
Multibac: baculovirus-mediated multigene DNA cargo delivery in insect and mammalian cells K Gupta, C Tölzer, D Sari-Ak, DJ Fitzgerald, C Schaffitzel, I Berger Viruses 11 (3), 198, 2019 | 41 | 2019 |
Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus F Aulicino, M Pelosse, C Toelzer, J Capin, E Ilegems, P Meysami, ... Nucleic Acids Research 50 (13), 7783-7799, 2022 | 36 | 2022 |
Large expert-curated database for benchmarking document similarity detection in biomedical literature search P Brown, Y Zhou Database 2019, baz085, 2019 | 36 | 2019 |
The free fatty acid–binding pocket is a conserved hallmark in pathogenic β-coronavirus spike proteins from SARS-CoV to Omicron C Toelzer, K Gupta, SKN Yadav, L Hodgson, MK Williamson, D Buzas, ... Science advances 8 (47), eadc9179, 2022 | 35 | 2022 |
Arabidopsis immunity regulator EDS1 in a PAD4/SAG101-unbound form is a monomer with an inherently inactive conformation M Voss, C Toelzer, DD Bhandari, JE Parker, K Niefind Journal of structural biology 208 (3), 107390, 2019 | 30 | 2019 |
Control of Chiral Magnetism Through Electric Fields in Multiferroic Compounds above the Long-Range Multiferroic Transition MB J. Stein, M. Baum, S. Holbein, T. Finger, T. Cronert, C. Tölzer, T ... Physical Review Letters, 2017 | 28 | 2017 |
Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2 K Gupta, C Toelzer, MK Williamson, DK Shoemark, ASF Oliveira, ... Nature communications 13 (1), 222, 2022 | 27 | 2022 |
Biological properties and structural study of new aminoalkyl derivatives of benzimidazole and benzotriazole, dual inhibitors of CK2 and PIM1 kinases K Chojnacki, P Wińska, M Wielechowska, E Łukowska-Chojnacka, ... Bioorganic Chemistry 80, 266-275, 2018 | 24 | 2018 |
The MultiBac BEVS: basics, applications, performance and recent developments B Gorda, C Toelzer, F Aulicino, I Berger Methods in enzymology 660, 129-154, 2021 | 16 | 2021 |
Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy C Toelzer, K Gupta, I Berger, C Schaffitzel Biological Crystallography 79 (2), 111-121, 2023 | 15 | 2023 |
Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder … JC Bufton, KT Powers, JYA Szeto, C Toelzer, I Berger, C Schaffitzel Nucleic acids research 50 (10), 5934-5947, 2022 | 15 | 2022 |
Synthesis, biological properties and structural study of new halogenated azolo [4, 5-b] pyridines as inhibitors of CK2 kinase K Chojnacki, D Lindenblatt, P Wińska, M Wielechowska, C Toelzer, ... Bioorganic chemistry 106, 104502, 2021 | 14 | 2021 |
The MultiBac system: a perspective I Berger, C Tölzer, K Gupta Emerging Topics in Life Sciences 3 (5), 477-482, 2019 | 8 | 2019 |
A novel esterase subfamily with α/β‐hydrolase fold suggested by structures of two bacterial enzymes homologous to l‐homoserine O‐acetyl transferases C Tölzer, S Pal, H Watzlawick, J Altenbuchner, K Niefind FEBS letters 590 (1), 174-184, 2016 | 8 | 2016 |
Crystallization and preliminary crystallographic analysis of cgHle, a homoserine acetyltransferase homologue, from Corynebacterium glutamicum C Tölzer, S Pal, H Watzlawick, J Altenbuchner, K Niefind Structural Biology and Crystallization Communications 65 (1), 34-38, 2009 | 6 | 2009 |
Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and … D Bakonyi, C Toelzer, M Stricker, W Hummel, K Niefind, H Gröger Catalysts 10 (11), 1281, 2020 | 4 | 2020 |
Structural basis for cell-type specific evolution of viral fitness by SARS-CoV-2 K Gupta, C Toelzer, MK Williamson, DK Shoemark, ASF Oliveira, ... bioRxiv, 2021.05. 11.443384, 2021 | 3 | 2021 |
Improved protein-crystal identification by using 2, 2, 2-trichloroethanol as a fluorescence enhancer C Pichlo, C Toelzer, K Chojnacki, S Öcal, M Uthoff, S Ruegenberg, ... Structural Biology and Crystallization Communications 74 (5), 307-314, 2018 | 3 | 2018 |