Accurate estimation of cell composition in bulk expression through robust integration of single-cell information B Jew, M Alvarez, E Rahmani, Z Miao, A Ko, KM Garske, JH Sul, ... Nature communications 11 (1), 1971, 2020 | 364 | 2020 |
Phenotype-specific enrichment of Mendelian disorder genes near GWAS regions across 62 complex traits MK Freund, KS Burch, H Shi, N Mancuso, G Kichaev, KM Garske, DZ Pan, ... The American Journal of Human Genetics 103 (4), 535-552, 2018 | 97 | 2018 |
Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS DZ Pan, KM Garske, M Alvarez, YV Bhagat, J Boocock, E Nikkola, Z Miao, ... Nature communications 9 (1), 1512, 2018 | 94 | 2018 |
Enhancing droplet-based single-nucleus RNA-seq resolution using the semi-supervised machine learning classifier DIEM M Alvarez, E Rahmani, B Jew, KM Garske, Z Miao, JN Benhammou, ... Scientific reports 10 (1), 11019, 2020 | 83 | 2020 |
The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance Z Miao, M Alvarez, A Ko, Y Bhagat, E Rahmani, B Jew, S Heinonen, ... PLoS genetics 16 (9), e1009018, 2020 | 71 | 2020 |
Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI BW van der Kolk, S Saari, A Lovric, M Arif, M Alvarez, A Ko, Z Miao, ... Cell Reports Medicine 2 (4), 2021 | 52 | 2021 |
Identification of 90 NAFLD GWAS loci and establishment of NAFLD PRS and causal role of NAFLD in coronary artery disease Z Miao, KM Garske, DZ Pan, A Koka, D Kaminska, V Männistö, ... Human Genetics and Genomics Advances 3 (1), 2022 | 39 | 2022 |
Serum aromatic and branched‐chain amino acids associated with NASH demonstrate divergent associations with serum lipids VD de Mello, R Sehgal, V Männistö, A Klåvus, E Nilsson, A Perfilyev, ... Liver International 41 (4), 754-763, 2021 | 37 | 2021 |
Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes DZ Pan, Z Miao, C Comenho, S Rajkumar, A Koka, SHT Lee, M Alvarez, ... Genome medicine 13, 1-20, 2021 | 36 | 2021 |
Differential mitochondrial gene expression in adipose tissue following weight loss induced by diet or bariatric surgery BW van Der Kolk, M Muniandy, D Kaminska, M Alvarez, A Ko, Z Miao, ... The Journal of Clinical Endocrinology & Metabolism 106 (5), 1312-1324, 2021 | 30 | 2021 |
Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease I Selvarajan, A Toropainen, KM Garske, ML Rodríguez, A Ko, Z Miao, ... The American Journal of Human Genetics 108 (3), 411-430, 2021 | 29 | 2021 |
Reverse gene–environment interaction approach to identify variants influencing body-mass index in humans KM Garske, DZ Pan, Z Miao, YV Bhagat, C Comenho, CR Robles, ... Nature metabolism 1 (6), 630-642, 2019 | 23 | 2019 |
ASElux: an ultra-fast and accurate allelic reads counter Z Miao, M Alvarez, P Pajukanta, A Ko Bioinformatics 34 (8), 1313-1320, 2018 | 22 | 2018 |
Accurate estimation of cell composition in bulk expression through robust integration of single-cell information. Nat. Commun. 11, 1971 B Jew, M Alvarez, E Rahmani, Z Miao, A Ko, KM Garske, JH Sul, ... Medline, 2020 | 17 | 2020 |
Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease N Darci-Maher, M Alvarez, UT Arasu, I Selvarajan, SHT Lee, DZ Pan, ... EBioMedicine 92, 2023 | 16 | 2023 |
Accurate estimation of cell composition in bulk expression through robust integration of single-cell information. Nat Commun. 2020; 11 (1): 1971 B Jew, M Alvarez, E Rahmani, Z Miao, A Ko, KM Garske Nature Publishing Group, 2020 | 15 | 2020 |
Increased body mass index is linked to systemic inflammation through altered chromatin co-accessibility in human preadipocytes KM Garske, A Kar, C Comenho, B Balliu, DZ Pan, YV Bhagat, ... Nature Communications 14 (1), 4214, 2023 | 12 | 2023 |
Molecular characterization of the lipid genome-wide association study signal on chromosome 18q11. 2 implicates HNF4A-mediated regulation of the TMEM241 gene A Rodríguez, L Gonzalez, A Ko, M Alvarez, Z Miao, Y Bhagat, E Nikkola, ... Arteriosclerosis, Thrombosis, and Vascular Biology 36 (7), 1350-1355, 2016 | 11 | 2016 |
Single nucleus RNA-sequencing integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic … SHT Lee, KM Garske, UT Arasu, A Kar, Z Miao, M Alvarez, A Koka, ... EBioMedicine 106, 2024 | 4 | 2024 |
Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS. Nat Commun. 2018; 9: 1512 DZ Pan, KM Garske, M Alvarez, YV Bhagat, J Boocock, E Nikkola, Z Miao, ... | 3 | |