| Sodium channelopathies in neurodevelopmental disorders MH Meisler, SF Hill, W Yu Nature Reviews Neuroscience 22 (3), 152-166, 2021 | 138 | 2021 |
| Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome GM Lenk, P Jafar‐Nejad, SF Hill, LD Huffman, CE Smolen, JL Wagnon, ... Annals of neurology 87 (3), 339-346, 2020 | 129 | 2020 |
| Assembly of the complexes of oxidative phosphorylation triggers the remodeling of cardiolipin Y Xu, M Anjaneyulu, A Donelian, W Yu, ML Greenberg, M Ren, ... Proceedings of the National Academy of Sciences 116 (23), 11235-11240, 2019 | 75 | 2019 |
| Inositol depletion, GSK3 inhibition and bipolar disorder W Yu, ML Greenberg Future Neurology 11 (2), 135-148, 2016 | 66 | 2016 |
| Cardiolipin-induced activation of pyruvate dehydrogenase links mitochondrial lipid biosynthesis to TCA cycle function Y Li, W Lou, V Raja, S Denis, W Yu, MW Schmidtke, CA Reynolds, ... Journal of Biological Chemistry 294 (30), 11568-11578, 2019 | 46 | 2019 |
| Inositol Hexakisphosphate Kinase 1 (IP6K1) Regulates Inositol Synthesis in Mammalian Cells*♦ W Yu, C Ye, ML Greenberg Journal of Biological Chemistry 291 (20), 10437-10444, 2016 | 33 | 2016 |
| MCK1 is a novel regulator of myo-inositol phosphate synthase (MIPS) that is required for inhibition of inositol synthesis by the mood stabilizer valproate W Yu, J Daniel, D Mehta, KR Maddipati, ML Greenberg PloS one 12 (8), e0182534, 2017 | 26 | 2017 |
| Structure, function, and dynamics of the Gα binding domain of Ric-8A B Zeng, TC Mou, TI Doukov, A Steiner, W Yu, M Papasergi-Scott, GG Tall, ... Structure 27 (7), 1137-1147. e5, 2019 | 23 | 2019 |
| Regulation of inositol biosynthesis: balancing health and pathophysiology KC Case, M Salsaa, W Yu, ML Greenberg Lipid Signaling in Human Diseases, 221-260, 2020 | 22 | 2020 |
| Valproate inhibits mitochondrial bioenergetics and increases glycolysis in Saccharomyces cerevisiae M Salsaa, B Pereira, J Liu, W Yu, S Jadhav, M Hüttemann, ML Greenberg Scientific Reports 10 (1), 11785, 2020 | 20 | 2020 |
| Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse W Yu, SF Hill, JG Xenakis, F Pardo‐Manuel de Villena, JL Wagnon, ... Epilepsia 61 (12), 2847-2856, 2020 | 19 | 2020 |
| Genetic re-engineering of polyunsaturated phospholipid profile of Saccharomyces cerevisiae identifies a novel role for Cld1 in mitigating the effects of cardiolipin peroxidation W Lou, HC Ting, CA Reynolds, YY Tyurina, VA Tyurin, Y Li, J Ji, W Yu, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2018 | 18 | 2018 |
| Astrocyte reactivity in a mouse model of SCN8A epileptic encephalopathy JA Thompson, RM Miralles, ER Wengert, PK Wagley, W Yu, IC Wenker, ... Epilepsia Open 7 (2), 280-292, 2022 | 13 | 2022 |
| Spontaneous seizures and elevated seizure susceptibility in response to somatic mutation of sodium channel Scn8a in the mouse W Yu, CE Smolen, SF Hill, MH Meisler Human Molecular Genetics 30 (10), 902-907, 2021 | 7 | 2021 |
| Production of Phosphorylated Ric-8A proteins using protein kinase CK2 W Yu, M Yu, MM Papasergi-Scott, GG Tall Protein expression and purification 154, 98-103, 2019 | 7 | 2019 |
| Valproate inhibits glucose-stimulated insulin secretion in beta cells NR Yedulla, AR Naik, KM Kokotovich, W Yu, ML Greenberg, BP Jena Histochemistry and cell biology 150, 395-401, 2018 | 6 | 2018 |
| Long‐Term Downregulation of the Sodium Channel Gene Scn8a Is Therapeutic in Mouse Models of SCN8A Epilepsy SF Hill*, W Yu*, J Ziobro, S Chalasani, F Reger, MH Meisler Annals of Neurology 95 (4), 754-759, 2024 | 4 | 2024 |
| Correction of the hypomorphic Gabra2 splice site variant in mouse strain C57BL/6J modifies the severity of Scn8a encephalopathy W Yu, MK Mulligan, RW Williams, MH Meisler Human Genetics and Genomics Advances 3 (1), 2022 | 3 | 2022 |
| Allele‐Specific Editing of a Dominant SCN8A Epilepsy Variant Protects against Seizures and Lethality in a Murine Model W Yu, SF Hill, Y Huang, L Zhu, Y Demetriou, J Ziobro, F Reger, X Jia, ... Annals of Neurology 96 (5), 958-969, 2024 | 1 | 2024 |
| Dentate gyrus granule cells are a locus of pathology in Scn8a developmental encephalopathy W Yu, SF Hill, L Zhu, Y Demetriou, F Reger, J Mattis, MH Meisler Neurobiology of Disease 199, 106591, 2024 | 1 | 2024 |