Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature TA Briggs, GI Rice, S Daly, J Urquhart, H Gornall, B Bader-Meunier, ... Nature genetics 43 (2), 127-131, 2011 | 276 | 2011 |
Type I IFN system in the development and manifestations of SLE KB Elkon, A Wiedeman Current opinion in rheumatology 24 (5), 499-505, 2012 | 176 | 2012 |
Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression AE Wiedeman, VS Muir, MG Rosasco, HA DeBerg, S Presnell, B Haas, ... The Journal of clinical investigation 130 (1), 480-490, 2020 | 159 | 2020 |
Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells NV Giltiay, CP Chappell, X Sun, N Kolhatkar, TH Teal, AE Wiedeman, ... Journal of Experimental Medicine 210 (12), 2773-2789, 2013 | 116 | 2013 |
Active systemic lupus erythematosus is associated with failure of antigen-presenting cells to express programmed death ligand-1 N Mozaffarian, AE Wiedeman, AM Stevens Rheumatology 47 (9), 1335-1341, 2008 | 105 | 2008 |
TNF-α and TGF-β counter-regulate PD-L1 expression on monocytes in systemic lupus erythematosus JN Ou, AE Wiedeman, AM Stevens Scientific reports 2 (1), 295, 2012 | 97 | 2012 |
Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes DM Santer, AE Wiedeman, TH Teal, P Ghosh, KB Elkon The Journal of Immunology 188 (2), 902-915, 2012 | 77 | 2012 |
Tartrate‐resistant acid phosphatase deficiency in the predisposition to systemic lupus erythematosus J An, TA Briggs, A Dumax‐Vorzet, ME Alarcón‐Riquelme, A Belot, ... Arthritis & rheumatology 69 (1), 131-142, 2017 | 67 | 2017 |
Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice X Sun, A Wiedeman, N Agrawal, TH Teal, L Tanaka, KL Hudkins, ... The Journal of Immunology 190 (6), 2536-2543, 2013 | 66 | 2013 |
Contrasting mechanisms of interferon‐α inhibition by intravenous immunoglobulin after induction by immune complexes versus Toll‐like receptor agonists AE Wiedeman, DM Santer, W Yan, S Miescher, F Käsermann, KB Elkon Arthritis & Rheumatism 65 (10), 2713-2723, 2013 | 63 | 2013 |
A distinct GM-CSF+ T helper cell subset requires T-bet to adopt a TH1 phenotype and promote neuroinflammation J Rasouli, G Casella, S Yoshimura, W Zhang, D Xiao, J Garifallou, ... Science Immunology 5 (52), eaba9953, 2020 | 53 | 2020 |
Cytometry TOF identifies alveolar macrophage subtypes in acute respiratory distress syndrome ED Morrell, A Wiedeman, SA Long, SA Gharib, TE West, SJ Skerrett, ... JCI insight 3 (10), e99281, 2018 | 51 | 2018 |
Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity K Lambert, KG Moo, A Arnett, G Goel, A Hu, KJ Flynn, C Speake, ... Science translational medicine 14 (627), eabi4888, 2022 | 33 | 2022 |
A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with … C Mathieu, A Wiedeman, K Cerosaletti, SA Long, E Serti, L Cooney, ... Diabetologia 67 (1), 27-41, 2024 | 28 | 2024 |
Chemokines, soluble PD-L1, and immune cell hyporesponsiveness are distinct features of SARS-CoV-2 critical illness ED Morrell, PK Bhatraju, NA Sathe, J Lawson, L Mabrey, SE Holton, ... American Journal of Physiology-Lung Cellular and Molecular Physiology, 2022 | 25 | 2022 |
Dynein light chain family in Tetrahymena thermophila DE Wilkes, V Rajagopalan, CWC Chan, E Kniazeva, AE Wiedeman, ... Cell motility and the cytoskeleton 64 (2), 82-96, 2007 | 22 | 2007 |
The many faces of islet antigen‐specific CD8 T cells: clues to clinical outcome in type 1 diabetes AE Wiedeman, C Speake, SA Long Immunology and cell biology 99 (5), 475-485, 2021 | 18 | 2021 |
Guidelines for standardizing T‐cell cytometry assays to link biomarkers, mechanisms, and disease outcomes in type 1 diabetes JHM Yang, KA Ward‐Hartstonge, DJ Perry, JL Blanchfield, AL Posgai, ... European journal of immunology 52 (3), 372-388, 2022 | 12 | 2022 |
A phase 2 randomized trial with autologous polyclonal expanded regulatory T cells in children with new-onset type 1 diabetes C Bender, AE Wiedeman, A Hu, A Ylescupidez, WK Sietsema, KC Herold, ... Science Translational Medicine 16 (746), eadn2404, 2024 | 9 | 2024 |
Extending the marine microcosm laboratory H Van Ryswyk, EW Hall, SJ Petesch, AE Wiedeman Journal of chemical education 84 (2), 306, 2007 | 6 | 2007 |