Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen JG Jardine, T Ota, D Sok, M Pauthner, DW Kulp, O Kalyuzhniy, PD Skog, ... Science 349 (6244), 156-161, 2015 | 449 | 2015 |
Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex D Sok, MJ van Gils, M Pauthner, JP Julien, KL Saye-Francisco, J Hsueh, ... Proceedings of the National Academy of Sciences 111 (49), 17624-17629, 2014 | 394 | 2014 |
Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance KM Cirelli, DG Carnathan, B Nogal, JT Martin, OL Rodriguez, ... Cell 177 (5), 1153-1171. e28, 2019 | 368 | 2019 |
Elicitation of robust tier 2 neutralizing antibody responses in nonhuman primates by HIV envelope trimer immunization using optimized approaches M Pauthner, C Havenar-Daughton, D Sok, JP Nkolola, R Bastidas, ... Immunity 46 (6), 1073-1088. e6, 2017 | 316 | 2017 |
Global site-specific N-glycosylation analysis of HIV envelope glycoprotein L Cao, JK Diedrich, DW Kulp, M Pauthner, L He, SKR Park, D Sok, CY Su, ... Nature communications 8 (1), 14954, 2017 | 259 | 2017 |
Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies LE McCoy, MJ van Gils, G Ozorowski, T Messmer, B Briney, JE Voss, ... Cell reports 16 (9), 2327-2338, 2016 | 257 | 2016 |
A broadly neutralizing antibody targets the dynamic HIV envelope trimer apex via a long, rigidified, and anionic β-hairpin structure JH Lee, R Andrabi, CY Su, A Yasmeen, JP Julien, L Kong, NC Wu, ... Immunity 46 (4), 690-702, 2017 | 252 | 2017 |
Electron-microscopy-based epitope mapping defines specificities of polyclonal antibodies elicited during HIV-1 BG505 envelope trimer immunization M Bianchi, HL Turner, B Nogal, CA Cottrell, D Oyen, M Pauthner, ... Immunity 49 (2), 288-300. e8, 2018 | 209 | 2018 |
Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice D Sok, B Briney, JG Jardine, DW Kulp, S Menis, M Pauthner, A Wood, ... Science 353 (6307), 1557-1560, 2016 | 175 | 2016 |
Direct probing of germinal center responses reveals immunological features and bottlenecks for neutralizing antibody responses to HIV Env trimer C Havenar-Daughton, DG Carnathan, AT de la Peña, M Pauthner, ... Cell reports 17 (9), 2195-2209, 2016 | 173 | 2016 |
Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding DW Kulp, JM Steichen, M Pauthner, X Hu, T Schiffner, A Liguori, ... Nature communications 8 (1), 1655, 2017 | 158 | 2017 |
An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability MJ Van Gils, TLGM Van Den Kerkhof, G Ozorowski, CA Cottrell, D Sok, ... Nature microbiology 2 (2), 1-10, 2016 | 157 | 2016 |
A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans D Sok, M Pauthner, B Briney, JH Lee, KL Saye-Francisco, J Hsueh, ... Immunity 45 (1), 31-45, 2016 | 156 | 2016 |
Vaccine-induced protection from homologous tier 2 SHIV challenge in nonhuman primates depends on serum-neutralizing antibody titers MG Pauthner, JP Nkolola, C Havenar-Daughton, B Murrell, SM Reiss, ... Immunity 50 (1), 241-252. e6, 2019 | 152 | 2019 |
Minimally mutated HIV-1 broadly neutralizing antibodies to guide reductionist vaccine design JG Jardine, D Sok, JP Julien, B Briney, A Sarkar, CH Liang, EA Scherer, ... PLoS pathogens 12 (8), e1005815, 2016 | 144 | 2016 |
Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer L Cao, M Pauthner, R Andrabi, K Rantalainen, Z Berndsen, JK Diedrich, ... Nature communications 9 (1), 3693, 2018 | 139 | 2018 |
Ebola virus transmission initiated by relapse of systemic Ebola virus disease P Mbala-Kingebeni, C Pratt, M Mutafali-Ruffin, MG Pauthner, F Bile, ... New England Journal of Medicine 384 (13), 1240-1247, 2021 | 95 | 2021 |
A meta-analysis of passive immunization studies shows that serum-neutralizing antibody titer associates with protection against SHIV challenge A Pegu, B Borate, Y Huang, MG Pauthner, AJ Hessell, B Julg, ... Cell host & microbe 26 (3), 336-346. e3, 2019 | 95 | 2019 |
CodY orchestrates the expression of virulence determinants in emetic Bacillus cereus by impacting key regulatory circuits E Frenzel, V Doll, M Pauthner, G Lücking, S Scherer, M Ehling‐Schulz Molecular microbiology 85 (1), 67-88, 2012 | 94 | 2012 |
Global site-specific analysis of glycoprotein N-glycan processing L Cao, JK Diedrich, Y Ma, N Wang, M Pauthner, SKR Park, CM Delahunty, ... Nature protocols 13 (6), 1196-1212, 2018 | 89 | 2018 |