Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignancies AL Wong, RA Soo, DS Tan, SC Lee, JS Lim, PC Marban, LR Kong, ... Annals of Oncology 26 (5), 998-1005, 2015 | 197 | 2015 |
Anti-tumor efficacy of Selinexor (KPT-330) in gastric cancer is dependent on nuclear accumulation of p53 tumor suppressor VV Subhash, MS Yeo, L Wang, SH Tan, FY Wong, WL Thuya, WL Tan, ... Scientific reports 8 (1), 12248, 2018 | 92 | 2018 |
Method development and validation for rapid quantification of hydroxychloroquine in human blood using liquid chromatography–tandem mass spectrometry LZ Wang, RYL Ong, TM Chin, WL Thuya, SC Wan, ALA Wong, SY Chan, ... Journal of pharmaceutical and biomedical analysis 61, 86-92, 2012 | 83 | 2012 |
Glucuronidation by UGT1A1 is the dominant pathway of the metabolic disposition of belinostat in liver cancer patients LZ Wang, J Ramírez, W Yeo, MYM Chan, WL Thuya, JYA Lau, SC Wan, ... PLoS One 8 (1), e54522, 2013 | 77 | 2013 |
Pan-HDAC inhibition by panobinostat mediates chemosensitization to carboplatin in non-small cell lung cancer via attenuation of EGFR signaling L Wang, NLX Syn, VV Subhash, Y Any, WL Thuya, ESH Cheow, L Kong, ... Cancer letters 417, 152-160, 2018 | 72 | 2018 |
Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its development L Wang, J Zhang, PS Ong, WL Thuya, R Soo, ALA Wong, WP Yong, ... Oncotarget 7 (28), 44790, 2016 | 65 | 2016 |
A novel combinatorial strategy using Seliciclib® and Belinostat® for eradication of non-small cell lung cancer via apoptosis induction and BID activation PS Ong, L Wang, DMH Chia, JYX Seah, LR Kong, WL Thuya, ... Cancer letters 381 (1), 49-57, 2016 | 48 | 2016 |
Rapid determination of gefitinib and its main metabolite, O-desmethyl gefitinib in human plasma using liquid chromatography–tandem mass spectrometry LZ Wang, MYX Lim, TM Chin, WL Thuya, PL Nye, A Wong, SY Chan, ... Journal of Chromatography B 879 (22), 2155-2161, 2011 | 44 | 2011 |
Quantification of L‐ergothioneine in human plasma and erythrocytes by liquid chromatography‐tandem mass spectrometry LZ Wang, WL Thuya, DSL Toh, MGL Lie, JYA Lau, LR Kong, SC Wan, ... Journal of Mass Spectrometry 48 (3), 406-412, 2013 | 26 | 2013 |
Inhibitory potential of resveratrol in cancer metastasis: from biology to therapy B Song, W Wang, X Tang, RMWJ Goh, WL Thuya, PCL Ho, L Chen, ... Cancers 15 (10), 2758, 2023 | 25 | 2023 |
Validation of a rapid and sensitive LC-MS/MS method for determination of exemestane and its metabolites, 17β-hydroxyexemestane and 17β-hydroxyexemestane-17-O-β-D-glucuronide … LZ Wang, SH Goh, ALA Wong, WL Thuya, JYA Lau, SC Wan, SC Lee, ... PloS one 10 (3), e0118553, 2015 | 21 | 2015 |
Simultaneous determination of raltegravir and raltegravir glucuronide in human plasma by liquid chromatography–tandem mass spectrometric method LZ Wang, LSU Lee, WL Thuya, GH Soon, LR Kong, PL Nye, ... Journal of mass spectrometry 46 (2), 202-208, 2011 | 21 | 2011 |
FAM3C in circulating tumor-derived extracellular vesicles promotes non-small cell lung cancer growth in secondary sites WL Thuya, LR Kong, NL Syn, LW Ding, ESH Cheow, RTX Wong, T Wang, ... Theranostics 13 (2), 621, 2023 | 18 | 2023 |
FBXW5 promotes tumorigenesis and metastasis in gastric cancer via activation of the FAK-Src signaling pathway MS Yeo, V Vijay Subhash, K Suda, H Emrah Balcıoğlu, S Zhou, WL Thuya, ... Cancers 11 (6), 836, 2019 | 18 | 2019 |
A sensitive liquid chromatography-tandem mass spectrometry method for the determination of nimbolide in mouse serum: Application to a preclinical pharmacokinetics study L Wang, DDK Phan, N Syn, X Xiang, H Song, WL Thuya, S Yang, ... Pharmaceutics 10 (3), 123, 2018 | 8 | 2018 |
Exosomal protein FAM3C as a potential novel biomarker for non-small cell lung cancer. LZ Wang, RA Soo, WL Thuya, TT Wang, T Guo, JA Lau, FC Wong, ... Journal of Clinical Oncology 32 (15_suppl), e22162-e22162, 2014 | 3 | 2014 |
Hsp27 expression does not affect anti-cancer drug sensitivity but promote cell proliferation of lung squamous cell carcinoma in vitro PY Ong, WL Thuya, LR Kong, JYA Lau, FC Wong, SC Wan, ALA Wong, ... J Pharmacol Drug Metab 1, 1-3, 2014 | 2 | 2014 |
Insights into IL-6/JAK/STAT3 Signaling in the Tumor Microenvironment: Implications for Cancer Therapy WL Thuya, C Yang, PCL Ho, ALA Wong, L Wang, J Zhou, C Nicot, ... Cytokine & Growth Factor Reviews, 2025 | | 2025 |
Exosome autoantibody biomarkers for detection of lung cancer WL Thuya, JM Peyper, ND Anuar, A Anwar, R Gudimella, NH Rutt, ... Military Medical Research 11 (1), 72, 2024 | | 2024 |
Tumor-derived extracellular vesicles convey solute transporters to induce bioenergetic dependence shift contributing to treatment resistance J Hirpara, WL Thuya, SH Cheow, K Fernando, JQ Eu, L Wang, ALA Wong, ... Theranostics 14 (16), 6350, 2024 | | 2024 |