Sequentially responsive shell‐stacked nanoparticles for deep penetration into solid tumors J Chen, J Ding, Y Wang, J Cheng, S Ji, X Zhuang, X Chen Advanced Materials 29 (32), 1701170, 2017 | 409 | 2017 |
Engineered nanomedicines with enhanced tumor penetration J Ding#, J Chen#, L Gao#, Z Jiang, Y Zhang, M Li, Q Xiao, SS Lee, ... Nano Today 29, 100800, 2019 | 369 | 2019 |
Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3 M Qiu, Z Glass, J Chen, M Haas, X Jin, X Zhao, X Rui, Z Ye, Y Li, F Zhang, ... Proceedings of the National Academy of Sciences 118 (10), e2020401118, 2021 | 324 | 2021 |
Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis M Qiu, Y Tang, J Chen, R Muriph, Z Ye, C Huang, J Evans, EP Henske, ... Proceedings of the national academy of sciences 119 (8), e2116271119, 2022 | 312 | 2022 |
Lipid nanoparticle-mediated lymph node–targeting delivery of mRNA cancer vaccine elicits robust CD8+ T cell response J Chen, Z Ye, C Huang, M Qiu, D Song, Y Li, Q Xu Proceedings of the National Academy of Sciences 119 (34), e2207841119, 2022 | 297 | 2022 |
Biocompatible reduction-responsive polypeptide micelles as nanocarriers for enhanced chemotherapy efficacy in vitro J Ding, J Chen, D Li, C Xiao, J Zhang, C He, X Zhuang, X Chen Journal of Materials Chemistry B 1 (1), 69-81, 2013 | 161 | 2013 |
Targeted pH-responsive polyion complex micelle for controlled intracellular drug delivery P Zheng, Y Liu, J Chen, W Xu, G Li, J Ding Chinese Chemical Letters 31 (5), 1178-1182, 2020 | 154 | 2020 |
Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injection F Ma, L Yang, Z Sun, J Chen, X Rui, Z Glass, Q Xu Science Advances 6 (30), eabb4429, 2020 | 148 | 2020 |
Receptor and microenvironment dual-recognizable nanogel for targeted chemotherapy of highly metastatic malignancy J Chen, J Ding, W Xu, T Sun, H Xiao, X Zhuang, X Chen Nano letters 17 (7), 4526-4533, 2017 | 144 | 2017 |
Imidazole‐based Synthetic Lipidoids for In Vivo mRNA Delivery into Primary T Lymphocytes X Zhao#, J Chen#, M Qiu, Y Li, Z Glass, Q Xu Angew. Chem. Int. Ed. 59 (45), 20083-20089, 2020 | 140 | 2020 |
Component effect of stem cell-loaded thermosensitive polypeptide hydrogels on cartilage repair H Liu, Y Cheng, J Chen, F Chang, J Wang, J Ding, X Chen Acta biomaterialia 73, 103-111, 2018 | 128 | 2018 |
Mucoadhesive cationic polypeptide nanogel with enhanced penetration for efficient intravesical chemotherapy of bladder cancer H Guo, F Li, W Xu, J Chen, Y Hou, C Wang, J Ding, X Chen Advanced Science 5 (6), 1800004, 2018 | 122 | 2018 |
Smart transformable nanoparticles for enhanced tumor theranostics J Chen, Z Jiang, YS Zhang, J Ding, X Chen Applied Physics Reviews 8 (4), 2021 | 117 | 2021 |
Thermo-sensitive polypeptide hydrogel for locally sequential delivery of two-pronged antitumor drugs L Wei, J Chen, S Zhao, J Ding, X Chen Acta biomaterialia 58, 44-53, 2017 | 112 | 2017 |
Injectable hydrogel–microsphere construct with sequential degradation for locally synergistic chemotherapy Y Zheng, Y Cheng, J Chen, J Ding, M Li, C Li, J Wang, X Chen ACS applied materials & interfaces 9 (4), 3487-3496, 2017 | 111 | 2017 |
Positively charged polypeptide nanogel enhances mucoadhesion and penetrability of 10-hydroxycamptothecin in orthotopic bladder carcinoma H Guo, W Xu, J Chen, L Yan, J Ding, Y Hou, X Chen Journal of Controlled Release 259, 136-148, 2017 | 109 | 2017 |
Polyion complex micelles with gradient pH-sensitivity for adjustable intracellular drug delivery J Chen, J Ding, Y Zhang, C Xiao, X Zhuang, X Chen Polymer chemistry 6 (3), 397-405, 2015 | 92 | 2015 |
Current developments and challenges of mRNA vaccines J Chen, J Chen, Q Xu Annual Review of Biomedical Engineering 24 (1), 85-109, 2022 | 91 | 2022 |
Spatiotemporally targeted nanomedicine overcomes hypoxia-induced drug resistance of tumor cells after disrupting neovasculature J Chen, Z Jiang, W Xu, T Sun, X Zhuang, J Ding, X Chen Nano Letters 20 (8), 6191-6198, 2020 | 91 | 2020 |
In situ cancer vaccination using lipidoid nanoparticles J Chen#, M Qiu#, Z Ye, T Nyalile, Y Li, Z Glass, X Zhao, L Yang, J Chen, ... Science Advances 7 (19), eabf1244, 2021 | 90 | 2021 |