| Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution GCH Mo, B Ross, F Hertel, P Manna, X Yang, E Greenwald, C Booth, ... Nature methods 14 (4), 427-434, 2017 | 165 | 2017 |
| Synthetic approaches to protein phosphorylation Z Chen, PA Cole Current opinion in chemical biology 28, 115-122, 2015 | 146 | 2015 |
| Akt kinase activation mechanisms revealed using protein semisynthesis N Chu, AL Salguero, AZ Liu, Z Chen, DR Dempsey, SB Ficarro, ... Cell 174 (4), 897-907. e14, 2018 | 130 | 2018 |
| A tunable brake for HECT ubiquitin ligases Z Chen, H Jiang, W Xu, X Li, DR Dempsey, X Zhang, P Devreotes, ... Molecular cell 66 (3), 345-357. e6, 2017 | 105 | 2017 |
| Enzyme-catalyzed expressed protein ligation SH Henager, N Chu, Z Chen, D Bolduc, DR Dempsey, Y Hwang, J Wells, ... Nature methods 13 (11), 925-927, 2016 | 74 | 2016 |
| Molecular features of phosphatase and tensin homolog (PTEN) regulation by C-terminal phosphorylation Z Chen, DR Dempsey, SN Thomas, D Hayward, DM Bolduc, PA Cole Journal of Biological Chemistry 291 (27), 14160-14169, 2016 | 59 | 2016 |
| Inhibition of the STAT3 signaling pathway is involved in the antitumor activity of cepharanthine in SaOS2 cells Z Chen, C Huang, Y Yang, Y Ding, H Ou-Yang, Y Zhang, M Xu Acta pharmacologica Sinica 33 (1), 101-108, 2012 | 56 | 2012 |
| Site-Specific Protein Labeling with N-Hydroxysuccinimide-Esters and the Analysis of Ubiquitin Ligase Mechanisms DR Dempsey, H Jiang, JH Kalin, Z Chen, PA Cole Journal of the American Chemical Society 140 (30), 9374-9378, 2018 | 54 | 2018 |
| Enzymatic analysis of PTEN ubiquitylation by WWP2 and NEDD4-1 E3 ligases Z Chen, SN Thomas, DM Bolduc, X Jiang, X Zhang, C Wolberger, ... Biochemistry 55 (26), 3658-3666, 2016 | 43 | 2016 |
| Regulation of S-adenosylhomocysteine hydrolase by lysine acetylation Y Wang, JM Kavran, Z Chen, KR Karukurichi, DJ Leahy, PA Cole Journal of Biological Chemistry 289 (45), 31361-31372, 2014 | 32 | 2014 |
| The structural basis of PTEN regulation by multi-site phosphorylation DR Dempsey, T Viennet, R Iwase, E Park, S Henriquez, Z Chen, ... Nature structural & molecular biology 28 (10), 858-868, 2021 | 30 | 2021 |
| Comparative analysis of the catalytic regulation of NEDD4-1 and WWP2 ubiquitin ligases H Jiang, SN Thomas, Z Chen, CY Chiang, PA Cole Journal of Biological Chemistry 294 (46), 17421-17436, 2019 | 30 | 2019 |
| Inhibition of signal transducer and activator of transcription 3 and cyclooxygenase-2 is involved in radiosensitization of cepharanthine in HeLa cells Z Fang, Y Li, Z Chen, J Wang, L Zhu International Journal of Gynecologic Cancer 23 (4), 2013 | 27 | 2013 |
| Formation, recognition and bioactivities of a novel G-quadruplex in the STAT3 gene S Lin, S Li, Z Chen, X He, Y Zhang, X Xu, M Xu, G Yuan Bioorganic & medicinal chemistry letters 21 (19), 5987-5991, 2011 | 21 | 2011 |
| Mechanistic analysis of ghrelin-O-acyltransferase using substrate analogs MS Taylor, DR Dempsey, Y Hwang, Z Chen, N Chu, JD Boeke, PA Cole Bioorganic chemistry 62, 64-73, 2015 | 20 | 2015 |
| Enzymatic analysis of WWP2 E3 ubiquitin ligase using protein microarrays identifies autophagy-related substrates H Jiang, CY Chiang, Z Chen, S Nathan, G D’Agostino, JA Paulo, G Song, ... Journal of Biological Chemistry 298 (5), 2022 | 11 | 2022 |
| What's new about the mechanism of methotrexate action in psoriasis? Z Chen British Journal of Dermatology 179 (4), 2018 | 7 | 2018 |
| EstG is a novel esterase required for cell envelope integrity in Caulobacter AK Daitch, BC Orsburn, Z Chen, L Alvarez, CD Eberhard, K Sundararajan, ... Current Biology 33 (2), 228-240. e7, 2023 | 4 | 2023 |
| The biological functions of G-quadruplex Z Chen, MH Xiu, SF Li, M Xu Sheng li ke xue jin zhan [Progress in physiology] 41 (5), 329-334, 2010 | 4 | 2010 |
| Targeting E3 ubiquitin ligases to sensitize cancer radiation therapy Z Chen, W Xu Precision Radiation Oncology 3 (3), 105-110, 2019 | 2 | 2019 |