Pancreatic exocrine duct cells give rise to insulin-producing β cells during embryogenesis but not after birth M Solar, C Cardalda, I Houbracken, M Martín, MA Maestro, N De Medts, ... Developmental cell 17 (6), 849-860, 2009 | 605 | 2009 |
Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population D Laoui, E Van Overmeire, G Di Conza, C Aldeni, J Keirsse, Y Morias, ... Cancer research 74 (1), 24-30, 2014 | 449 | 2014 |
Nanobody-based targeting of the macrophage mannose receptor for effective in vivo imaging of tumor-associated macrophages K Movahedi, S Schoonooghe, D Laoui, I Houbracken, W Waelput, ... Cancer research 72 (16), 4165-4177, 2012 | 338 | 2012 |
Lineage tracing evidence for transdifferentiation of acinar to duct cells and plasticity of human pancreas I Houbracken, E de Waele, J Lardon, Z Ling, H Heimberg, I Rooman, ... Gastroenterology 141 (2), 731-741. e4, 2011 | 159 | 2011 |
The use of stem cells for pancreatic regeneration in diabetes mellitus L Bouwens, I Houbracken, JK Mfopou Nature Reviews Endocrinology 9 (10), 598-606, 2013 | 113 | 2013 |
Suppression of epithelial-to-mesenchymal transitioning enhances ex vivo reprogramming of human exocrine pancreatic tissue toward functional insulin-producing β-like cells MJ Lima, KR Muir, HM Docherty, R Drummond, NWA McGowan, S Forbes, ... Diabetes 62 (8), 2821-2833, 2013 | 82 | 2013 |
Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture J Baldan, I Houbracken, I Rooman, L Bouwens Scientific reports 9 (1), 1-12, 2019 | 37 | 2019 |
On the origin of pancreatic cancer: molecular tumor subtypes in perspective of exocrine cell plasticity E Backx, K Coolens, JL Van den Bossche, I Houbracken, E Espinet, ... Cellular and molecular gastroenterology and hepatology 13 (4), 1243-1253, 2022 | 36 | 2022 |
MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions E Backx, E Wauters, J Baldan, M Van Bulck, E Michiels, Y Heremans, ... Cell Death & Differentiation 28 (9), 2601-2615, 2021 | 35 | 2021 |
Acinar cells in the neonatal pancreas grow by self-duplication and not by neogenesis from duct cells I Houbracken, L Bouwens Scientific reports 7 (1), 1-10, 2017 | 27 | 2017 |
The quest for tissue stem cells in the pancreas and other organs, and their application in beta-cell replacement I Houbracken, L Bouwens The review of diabetic studies: RDS 7 (2), 112, 2010 | 25 | 2010 |
Gene delivery to pancreatic exocrine cells in vivo and in vitro I Houbracken, L Baeyens, P Ravassard, H Heimberg, L Bouwens BMC biotechnology 12, 1-12, 2012 | 20 | 2012 |
Pancreatic acinar cell fate relies on system xC- to prevent ferroptosis during stress Z Pan, JL Van den Bossche, E Rodriguez-Aznar, P Janssen, O Lara, ... Cell Death & Disease 14 (8), 536, 2023 | 9 | 2023 |
Acinar phenotype is preserved in human exocrine pancreas cells cultured at low temperature: implications for lineage-tracing of β-cell neogenesis JK Mfopou, I Houbracken, E Wauters, I Mathijs, I Song, E Himpe, J Baldan, ... Bioscience reports 36 (3), e00329, 2016 | 6 | 2016 |
Lineage tracing of pancreatic stem cells and beta cell regeneration I Houbracken, I Mathijs, L Bouwens Animal Models in Diabetes Research, 303-315, 2012 | 6 | 2012 |
Do cancer centres and palliative care wards routinely measure patients’ quality of life? An international cross-sectional survey study R Miranda, E Raemdonck, L Deliens, S Kaasa, C Zimmermann, G Rodin, ... Supportive Care in Cancer 31 (8), 499, 2023 | 5 | 2023 |
Genetic lineage tracing of beta cell neogenesis I Mathijs, I Houbracken, L Bouwens Animal Models in Diabetes Research, 317-322, 2012 | 3 | 2012 |
Spatial transcriptomic analysis of human Pancreatic Basal Cells reveals PTGES as a potential target for the Basal-Like subtype of Pancreatic Ductal Adenocarcinoma. JL Van den Bossche, M Van der Vliet, K Coolens, E Michiels, ... BE-PRECISE 2024, 2024 | | 2024 |
Acinar cell susceptibility for tumor development in the pancreas: Targeting the critical regulators for therapy Z Pan, JLV Bossche, E Rodriguez-Aznar, P Janssen, O Lara, G Ates, ... Cancer Research 84 (6_Supplement), 3378-3378, 2024 | | 2024 |
ΔNP63 defines an exocrine-committed multipotent progenitor subset in the murine pancreas K Coolens, M Van der Vliet, J Van Campenhout, N del Pozo, ... bioRxiv, 2024.12. 10.627728, 2024 | | 2024 |