| Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets Z Miao, MS Balzer, Z Ma, H Liu, J Wu, R Shrestha, T Aranyi, A Kwan, ... Nature communications 12 (1), 2277, 2021 | 176 | 2021 |
| Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease H Liu, T Doke, D Guo, X Sheng, Z Ma, J Park, HMT Vy, GN Nadkarni, ... Nature genetics 54 (7), 950-962, 2022 | 127 | 2022 |
| Single-cell analysis highlights differences in druggable pathways underlying adaptive or fibrotic kidney regeneration MS Balzer, T Doke, YW Yang, DL Aldridge, H Hu, H Mai, D Mukhi, Z Ma, ... Nature communications 13 (1), 4018, 2022 | 124 | 2022 |
| Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments X Sheng, Y Guan, Z Ma, J Wu, H Liu, C Qiu, S Vitale, Z Miao, MJ Seasock, ... Nature genetics 53 (9), 1322-1333, 2021 | 124 | 2021 |
| Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer’s disease M Jin, R Xu, L Wang, MM Alam, Z Ma, S Zhu, AC Martini, A Jadali, ... Cell Stem Cell 29 (7), 1135-1153. e8, 2022 | 97 | 2022 |
| The key role of NLRP3 and STING in APOL1-associated podocytopathy J Wu, A Raman, NJ Coffey, X Sheng, J Wahba, MJ Seasock, Z Ma, ... The Journal of clinical investigation 131 (20), 2021 | 96 | 2021 |
| Urinary single-cell profiling captures the cellular diversity of the kidney A Abedini, YO Zhu, S Chatterjee, G Halasz, K Devalaraja-Narashimha, ... Journal of the American Society of Nephrology 32 (3), 614-627, 2021 | 87 | 2021 |
| APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis J Wu, Z Ma, A Raman, P Beckerman, P Dhillon, D Mukhi, M Palmer, ... Immunity 54 (11), 2632-2649. e6, 2021 | 70 | 2021 |
| Transcriptome-wide association analysis identifies DACH1 as a kidney disease risk gene that contributes to fibrosis T Doke, S Huang, C Qiu, H Liu, Y Guan, H Hu, Z Ma, J Wu, Z Miao, ... The Journal of clinical investigation 131 (10), 2021 | 64 | 2021 |
| A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis Y Guan, X Liang, Z Ma, H Hu, H Liu, Z Miao, A Linkermann, JN Hellwege, ... Nature communications 12 (1), 5078, 2021 | 57 | 2021 |
| How to get started with single cell RNA sequencing data analysis MS Balzer, Z Ma, J Zhou, A Abedini, K Susztak Journal of the American Society of Nephrology 32 (6), 1279-1292, 2021 | 41 | 2021 |
| Spatially resolved human kidney multi-omics single cell atlas highlights the key role of the fibrotic microenvironment in kidney disease progression A Abedini, J Levinsohn, KA Klötzer, B Dumoulin, Z Ma, J Frederick, ... Biorxiv, 2022.10. 24.513598, 2022 | 36 | 2022 |
| Renal histologic analysis provides complementary information to kidney function measurement for patients with early diabetic or hypertensive disease GZ Quinn, A Abedini, H Liu, Z Ma, A Cucchiara, A Havasi, J Hill, ... Journal of the American Society of Nephrology 32 (11), 2863-2876, 2021 | 27 | 2021 |
| Genome-wide association studies identify the role of caspase-9 in kidney disease T Doke, S Huang, C Qiu, X Sheng, M Seasock, H Liu, Z Ma, M Palmer, ... Science advances 7 (45), eabi8051, 2021 | 22 | 2021 |
| Single-cell multi-omic and spatial profiling of human kidneys implicates the fibrotic microenvironment in kidney disease progression A Abedini, J Levinsohn, KA Klötzer, B Dumoulin, Z Ma, J Frederick, ... Nature genetics 56 (8), 1712-1724, 2024 | 21 | 2024 |
| Dnmt3a and Dnmt3b-decommissioned fetal enhancers are linked to kidney disease Y Guan, H Liu, Z Ma, SY Li, J Park, X Sheng, K Susztak Journal of the American Society of Nephrology 31 (4), 765-782, 2020 | 21 | 2020 |
| Single-cell transcriptomics and chromatin accessibility profiling elucidate the kidney-protective mechanism of mineralocorticoid receptor antagonists A Abedini, A Sánchez-Navaro, J Wu, KA Klötzer, Z Ma, B Poudel, T Doke, ... The Journal of Clinical Investigation 134 (1), 2024 | 15 | 2024 |
| Antisense oligonucleotides ameliorate kidney dysfunction in podocyte-specific APOL1 risk variant mice YW Yang, B Poudel, J Frederick, P Dhillon, R Shrestha, Z Ma, J Wu, ... Molecular Therapy 30 (7), 2491-2504, 2022 | 14 | 2022 |
| Generation of iPSC-based human-mouse microglial brain chimeras to study senescence of human microglia M Jin, Z Ma, P Jiang STAR protocols 3 (4), 101847, 2022 | 7 | 2022 |
| A Trisomy 21-linked Hematopoietic Gene Variant in Microglia Confers Resilience in Human iPSC Models of Alzheimer’s Disease M Jin, Z Ma, R Dang, H Zhang, R Kim, H Xue, J Pascual, S Finkbeiner, ... bioRxiv, 2024 | 3 | 2024 |