| Building epithelial architecture: insights from three-dimensional culture models LE O'Brien, MMP Zegers, KE Mostov Nature reviews Molecular cell biology 3 (7), 531-537, 2002 | 775 | 2002 |
| Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly LE O'Brien, TS Jou, AL Pollack, Q Zhang, SH Hansen, P Yurchenco, ... Nature cell biology 3 (9), 831-838, 2001 | 538 | 2001 |
| Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly H Li, J Janssens, M De Waegeneer, SS Kolluru, K Davie, V Gardeux, ... Science 375 (6584), eabk2432, 2022 | 516 | 2022 |
| Altered modes of stem cell division drive adaptive intestinal growth LE O'Brien, SS Soliman, X Li, D Bilder Cell 147 (3), 603-614, 2011 | 443 | 2011 |
| β1-integrin orients epithelial polarity via Rac1 and laminin W Yu, A Datta, P Leroy, LE O'Brien, G Mak, TS Jou, KS Matlin, KE Mostov, ... Molecular biology of the cell 16 (2), 433-445, 2005 | 421 | 2005 |
| Epithelial polarity and tubulogenesis in vitro MMP Zegers, LE O'Brien, W Yu, A Datta, KE Mostov Trends in cell biology 13 (4), 169-176, 2003 | 297 | 2003 |
| ERK and MMPs sequentially regulate distinct stages of epithelial tubule development LE O'Brien, K Tang, ES Kats, A Schutz-Geschwender, JH Lipschutz, ... Developmental cell 7 (1), 21-32, 2004 | 182 | 2004 |
| Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins JH Lipschutz, W Guo, LE O'Brien, YH Nguyen, P Novick, KE Mostov Molecular biology of the cell 11 (12), 4259-4275, 2000 | 167 | 2000 |
| Feedback regulation of steady-state epithelial turnover and organ size J Liang, S Balachandra, S Ngo, LE O’Brien Nature 548 (7669), 588-591, 2017 | 156 | 2017 |
| Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures W Yu, LE O'Brien, F Wang, H Bourne, KE Mostov, MMP Zegers Molecular biology of the cell 14 (2), 748-763, 2003 | 120 | 2003 |
| Beyond the niche: tissue-level coordination of stem cell dynamics LE O'Brien, D Bilder Annual review of cell and developmental biology 29 (1), 107-136, 2013 | 76 | 2013 |
| Long-term live imaging of the Drosophila adult midgut reveals real-time dynamics of division, differentiation and loss JL Martin, EN Sanders, P Moreno-Roman, LA Jaramillo Koyama, ... Elife 7, e36248, 2018 | 69 | 2018 |
| Morphological and biochemical analysis of Rac1 in three‐dimensional epithelial cell cultures LE O'Brien, W Yu, K Tang, TS Jou, MMP Zegers, KE Mostov Methods in enzymology 406, 676-691, 2006 | 63 | 2006 |
| Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly. Science 375, eabk2432 H Li, J Janssens, M De Waegeneer, SS Kolluru, K Davie, V Gardeux, ... | 48 | 2022 |
| Bellymount enables longitudinal, intravital imaging of abdominal organs and the gut microbiota in adult Drosophila LAJ Koyama, A Aranda-Díaz, YH Su, S Balachandra, JL Martin, ... PLoS Biology 18 (1), e3000567, 2020 | 37 | 2020 |
| Totally implantable system for venous access in children with cystic fibrosis J Cassey, WDA Ford, L O'Brien, AJ Martin Clinical pediatrics 27 (2), 91-95, 1988 | 36 | 1988 |
| Analysis of membrane traffic in polarized epithelial cells JH Lipschutz, LE O'Brien, Y Altschuler, D Avrahami, Y Nguyen, K Tang, ... Current Protocols in Cell Biology 12 (1), 15.5. 1-15.5. 18, 2001 | 29 | 2001 |
| Microfluidics for mechanobiology of model organisms AA Kim, AL Nekimken, S Fechner, LE O’Brien, BL Pruitt Methods in cell biology 146, 217-259, 2018 | 25 | 2018 |
| Disruption of EGF feedback by intestinal tumors and neighboring cells in Drosophila S Ngo, J Liang, YH Su, LE O’Brien Current Biology 30 (8), 1537-1546. e3, 2020 | 23 | 2020 |
| Regional specificity in the Drosophila midgut: setting boundaries with stem cells LE O’Brien Cell stem cell 13 (4), 375-376, 2013 | 21 | 2013 |
