دنبال کردن
Amanda Heslegrave
Amanda Heslegrave
Senior Research Associate University College London
ایمیل تأیید شده در ucl.ac.uk
عنوان
نقل شده توسط
نقل شده توسط
سال
Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease
A Heslegrave, W Heywood, R Paterson, N Magdalinou, J Svensson, ...
Molecular neurodegeneration 11, 1-7, 2016
3332016
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk
Y Deming, F Filipello, F Cignarella, C Cantoni, S Hsu, R Mikesell, Z Li, ...
Science translational medicine 11 (505), eaau2291, 2019
2632019
Molecular biomarkers of Alzheimer's disease: progress and prospects
T Lashley, JM Schott, P Weston, CE Murray, H Wellington, A Keshavan, ...
Disease models & mechanisms 11 (5), dmm031781, 2018
2342018
G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo
R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ...
EMBO molecular medicine 10 (1), 22-31, 2018
2272018
Modified ketogenic diet is associated with improved cerebrospinal fluid biomarker profile, cerebral perfusion, and cerebral ketone body uptake in older adults at risk for …
BJ Neth, A Mintz, C Whitlow, Y Jung, KS Sai, TC Register, D Kellar, ...
Neurobiology of aging 86, 54-63, 2020
1842020
Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington’s disease
LM Byrne, FB Rodrigues, EB Johnson, PA Wijeratne, E De Vita, ...
Science translational medicine 10 (458), eaat7108, 2018
1742018
Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay
WE Heywood, D Galimberti, E Bliss, E Sirka, RW Paterson, ...
Molecular neurodegeneration 10, 1-16, 2015
1722015
Diagnosis across the spectrum of progressive supranuclear palsy and corticobasal syndrome
E Jabbari, N Holland, V Chelban, PS Jones, R Lamb, C Rawlinson, T Guo, ...
JAMA neurology 77 (3), 377-387, 2020
1652020
Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia
C Heller, MS Foiani, K Moore, R Convery, M Bocchetta, M Neason, ...
Journal of Neurology, Neurosurgery & Psychiatry 91 (3), 263-270, 2020
1642020
Human induced pluripotent stem cell-derived microglia-like cells harboring TREM2 missense mutations show specific deficits in phagocytosis
P Garcia-Reitboeck, A Phillips, TM Piers, C Villegas-Llerena, M Butler, ...
Cell Reports 24 (9), 2300-2311, 2018
1582018
Familial Alzheimer’s disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta
C Arber, J Toombs, C Lovejoy, NS Ryan, RW Paterson, N Willumsen, ...
Molecular Psychiatry 25 (11), 2919-2931, 2020
1512020
Population-based blood screening for preclinical Alzheimer’s disease in a British birth cohort at age 70
A Keshavan, J Pannee, TK Karikari, JL Rodriguez, NJ Ashton, ...
Brain 144 (2), 434-449, 2021
1452021
Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury
NSN Graham, KA Zimmerman, F Moro, A Heslegrave, SA Maillard, ...
Science translational medicine 13 (613), eabg9922, 2021
1372021
Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase
N Stahmann, A Woods, K Spengler, A Heslegrave, R Bauer, S Krause, ...
Journal of Biological Chemistry 285 (14), 10638-10652, 2010
1272010
Differential levels of plasma biomarkers of neurodegeneration in Lewy body dementia, Alzheimer’s disease, frontotemporal dementia and progressive supranuclear palsy
L Chouliaras, A Thomas, M Malpetti, P Donaghy, J Kane, E Mak, ...
Journal of Neurology, Neurosurgery & Psychiatry 93 (6), 651-658, 2022
1192022
Cerebrospinal fluid in the differential diagnosis of Alzheimer’s disease: clinical utility of an extended panel of biomarkers in a specialist cognitive clinic
RW Paterson, CF Slattery, T Poole, JM Nicholas, NK Magdalinou, ...
Alzheimer's research & therapy 10, 1-11, 2018
1192018
Fluid biomarkers in frontotemporal dementia: past, present and future
IJ Swift, A Sogorb-Esteve, C Heller, M Synofzik, M Otto, C Graff, ...
Journal of Neurology, Neurosurgery & Psychiatry 92 (2), 204-215, 2021
1162021
Plasma phospho-tau181 in presymptomatic and symptomatic familial Alzheimer’s disease: a longitudinal cohort study
A O’Connor, TK Karikari, T Poole, NJ Ashton, J Lantero Rodriguez, ...
Molecular psychiatry 26 (10), 5967-5976, 2021
1082021
Exercise as a potential modulator of inflammation in patients with Alzheimer's disease measured in cerebrospinal fluid and plasma
CS Jensen, JM Bahl, LB Østergaard, P Høgh, L Wermuth, A Heslegrave, ...
Experimental gerontology 121, 91-98, 2019
1072019
Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer’s disease
J Stevenson-Hoare, A Heslegrave, G Leonenko, D Fathalla, E Bellou, ...
Brain 146 (2), 690-699, 2023
1062023
سیستم در حال حاضر قادر به انجام عملکرد نیست. بعداً دوباره امتحان کنید.
مقاله‌ها 1–20